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- Publisher Website: 10.1016/j.nano.2005.10.004
- Scopus: eid_2-s2.0-33645663597
- PMID: 17292103
- WOS: WOS:000209818200005
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Article: Investigation of angiotensin II type 1 receptor by atomic force microscopy with functionalized tip
Title | Investigation of angiotensin II type 1 receptor by atomic force microscopy with functionalized tip |
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Authors | |
Keywords | Atomic force microscopy Single-molecule recognition Tip functionalization Angiotensin II type 1 receptor |
Issue Date | 2005 |
Citation | Nanomedicine: Nanotechnology, Biology, and Medicine, 2005, v. 1, n. 4, p. 306-312 How to Cite? |
Abstract | Although membrane proteins consist of a substantial amount of the human genome and are the main drug targets, the study of cell membrane proteins in situ is complicated by the technical limitations. The recent development of atomic force microscopy (AFM) opens a new way to study the functions of cell membrane proteins in situ at the single-molecule level. A detailed procedure for investigation of angiotensin II type 1 receptor by AFM with functionalized tip is introduced in this article. Some prospective methods to improve the imaging resolution are also discussed. © 2005 Elsevier Inc. All rights reserved. |
Persistent Identifier | http://hdl.handle.net/10722/212862 |
ISSN | 2023 Impact Factor: 4.2 2023 SCImago Journal Rankings: 0.863 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Li, Guangyong | - |
dc.contributor.author | Xi, Ning | - |
dc.contributor.author | Wang, Donna H. | - |
dc.date.accessioned | 2015-07-28T04:05:15Z | - |
dc.date.available | 2015-07-28T04:05:15Z | - |
dc.date.issued | 2005 | - |
dc.identifier.citation | Nanomedicine: Nanotechnology, Biology, and Medicine, 2005, v. 1, n. 4, p. 306-312 | - |
dc.identifier.issn | 1549-9634 | - |
dc.identifier.uri | http://hdl.handle.net/10722/212862 | - |
dc.description.abstract | Although membrane proteins consist of a substantial amount of the human genome and are the main drug targets, the study of cell membrane proteins in situ is complicated by the technical limitations. The recent development of atomic force microscopy (AFM) opens a new way to study the functions of cell membrane proteins in situ at the single-molecule level. A detailed procedure for investigation of angiotensin II type 1 receptor by AFM with functionalized tip is introduced in this article. Some prospective methods to improve the imaging resolution are also discussed. © 2005 Elsevier Inc. All rights reserved. | - |
dc.language | eng | - |
dc.relation.ispartof | Nanomedicine: Nanotechnology, Biology, and Medicine | - |
dc.subject | Atomic force microscopy | - |
dc.subject | Single-molecule recognition | - |
dc.subject | Tip functionalization | - |
dc.subject | Angiotensin II type 1 receptor | - |
dc.title | Investigation of angiotensin II type 1 receptor by atomic force microscopy with functionalized tip | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.nano.2005.10.004 | - |
dc.identifier.pmid | 17292103 | - |
dc.identifier.scopus | eid_2-s2.0-33645663597 | - |
dc.identifier.volume | 1 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 306 | - |
dc.identifier.epage | 312 | - |
dc.identifier.isi | WOS:000209818200005 | - |
dc.identifier.issnl | 1549-9634 | - |