An optimisation framework of dendritic cells

Abstract

The paradigm of a signal cascading network of Dendritic Cells (DCs) underpins T-cells priming in the human immune system, which is one of the critical cell-mediated components in the innate immunity. This study is motivated by the immunological behavior of DCs, intracellular signal processing, and the architecture of the aforementioned signaldriven network in the maturation and migration processes. In parallel with these immuno-features and problem-solving techniques, a distributed DC-inspired framework is developed for resolving optimization problems. In the context of the study, the capabilities of the proposed framework are experimented in a small-scale resources scheduling problem. As of the obtained results, sets of high-quality solutions are produced, which also provide significant insights for the further development of DCmediated framework as presented in this paper.