Single-session pattern scan laser (Pascal) panretinal photocoagulation in proliferative diabetic retinopathy: a randomized study

Abstract

PURPOSE: To assess the safety and efficacy of single-session panretinal photocoagulation (PRP) using pattern scan laser in proliferative diabetic retinopathy (PDR). METHODS: Twenty-four treatment-naive PDR patients were randomized to 1700 or 2500 shots PRP in a single session. Central foveal thickness (CFT) was measured before and 1 week after laser by OCT. Regression of PDR was judged using fundus photos and fluorescein angiograms taken before and 3 months after laser. RESULTS: Between the 2 groups, there was no significant difference in the change of CFT or final visual acuity at 6 months. Neovascularization regression rate at 3 months was higher in the 2500-shot group than in the 1700-shot group (33.3% vs. 9.1%). CONCLUSION: Single-session PRP, with up to 2500 shots, using pattern scan laser, is safe in PDR, but more aggressive treatment is required to achieve a higher regression rate