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Article: Systematic review and meta-analysis on the efficacy of selective laser trabeculoplasty in open-angle glaucoma

TitleSystematic review and meta-analysis on the efficacy of selective laser trabeculoplasty in open-angle glaucoma
Authors
KeywordsMeta-analysis
Open angle glaucoma
Selective laser trabeculoplasty
Systematic review
Issue Date2015
Citation
Survey of Ophthalmology, 2015, v. 60 n. 1, p. 36-50 How to Cite?
AbstractSelective laser trabeculoplasty (SLT) is a relatively new type of laser used in treating open-angle glaucoma (OAG) and is reported to be equally efficacious to a first-line medication and argon laser trabeculoplasty (ALT). We summarize available evidence for considering SLT as an alternative treatment in OAG through systematic review and meta-analysis. Among OAG patients who range from newly diagnosed to those on maximally tolerated medical therapy, SLT results in a 6.9-35.9% intraocular pressure (IOP) reduction. Complications are rare and include an IOP spike requiring surgery, persistent macular edema, and corneal haze and thinning. Meta-analysis of randomized, controlled trials shows that SLT is non-inferior to ALT and medication in IOP reduction and also in achieving treatment success. Number of medications reduction is similar between SLT and ALT. More robust evidence is needed to determine its efficacy as a repeated procedure.
Persistent Identifierhttp://hdl.handle.net/10722/208492
ISSN
2023 Impact Factor: 5.1
2023 SCImago Journal Rankings: 1.899
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWong, MOen_US
dc.contributor.authorLee, WYJen_US
dc.contributor.authorChoy, BNen_US
dc.contributor.authorChan, JCen_US
dc.contributor.authorLai, JSen_US
dc.date.accessioned2015-03-11T07:06:24Z-
dc.date.available2015-03-11T07:06:24Z-
dc.date.issued2015en_US
dc.identifier.citationSurvey of Ophthalmology, 2015, v. 60 n. 1, p. 36-50en_US
dc.identifier.issn1879-3304en_US
dc.identifier.urihttp://hdl.handle.net/10722/208492-
dc.description.abstractSelective laser trabeculoplasty (SLT) is a relatively new type of laser used in treating open-angle glaucoma (OAG) and is reported to be equally efficacious to a first-line medication and argon laser trabeculoplasty (ALT). We summarize available evidence for considering SLT as an alternative treatment in OAG through systematic review and meta-analysis. Among OAG patients who range from newly diagnosed to those on maximally tolerated medical therapy, SLT results in a 6.9-35.9% intraocular pressure (IOP) reduction. Complications are rare and include an IOP spike requiring surgery, persistent macular edema, and corneal haze and thinning. Meta-analysis of randomized, controlled trials shows that SLT is non-inferior to ALT and medication in IOP reduction and also in achieving treatment success. Number of medications reduction is similar between SLT and ALT. More robust evidence is needed to determine its efficacy as a repeated procedure.en_US
dc.languageengen_US
dc.relation.ispartofSurvey of Ophthalmologyen_US
dc.subjectMeta-analysis-
dc.subjectOpen angle glaucoma-
dc.subjectSelective laser trabeculoplasty-
dc.subjectSystematic review-
dc.titleSystematic review and meta-analysis on the efficacy of selective laser trabeculoplasty in open-angle glaucomaen_US
dc.typeArticleen_US
dc.identifier.emailLee, WYJ: jackylee@hku.hken_US
dc.identifier.authorityLee, WYJ=rp01498en_US
dc.identifier.doi10.1016/j.survophthal.2014.06.006en_US
dc.identifier.pmid25113610-
dc.identifier.scopuseid_2-s2.0-84919390471-
dc.identifier.hkuros248668-
dc.identifier.volume60en_US
dc.identifier.issue1en_US
dc.identifier.spage36en_US
dc.identifier.epage50en_US
dc.identifier.isiWOS:000346892900002-
dc.identifier.issnl0039-6257-

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