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Article: Rosette-forming glioneuronal tumour of the lateral ventricle in a patient with neurofibromatosis 1

TitleRosette-forming glioneuronal tumour of the lateral ventricle in a patient with neurofibromatosis 1
Authors
KeywordsRosette-forming glioneuronal tumour
Neurofibromatosis 1
Lateral ventricle
RGNT
Issue Date2012
Citation
Journal of Clinical Neuroscience, 2012, v. 19, n. 8, p. 1180-1181 How to Cite?
AbstractWe report a 33-year-old man with neurofibromatosis type 1 (NF-1) with a rosette-forming glioneuronal tumour (RGNT) in the lateral ventricle. The patient had been treated with radiotherapy and chemotherapy for a typical juvenile pilocytic astrocytoma of the hypothalamus seven years prior. MRI revealed a contrast-enhancing mass in the anterior horn of the left lateral ventricle. Histological examination demonstrated two distinct regions characterised by a rosette-forming neurocytic component and an astrocytic predominant component. Immunohistochemical studies showed glial fibrillary acidic protein and S-100 positivity in the astrocytic component and neuron-specific enolase was positive in the neurocytic cells. Although RGNT has been reported at other sites within the central nervous system, this report documents a previously undescribed lateral ventricular location of a rare RGNT in an asymptomatic patient with NF-1. © 2011 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/207120
ISSN
2023 Impact Factor: 1.9
2023 SCImago Journal Rankings: 0.609
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorKemp, S.-
dc.contributor.authorAchan, Anita-
dc.contributor.authorNg, Thomas-
dc.contributor.authorDexter, Mark A J-
dc.date.accessioned2014-12-09T04:31:26Z-
dc.date.available2014-12-09T04:31:26Z-
dc.date.issued2012-
dc.identifier.citationJournal of Clinical Neuroscience, 2012, v. 19, n. 8, p. 1180-1181-
dc.identifier.issn0967-5868-
dc.identifier.urihttp://hdl.handle.net/10722/207120-
dc.description.abstractWe report a 33-year-old man with neurofibromatosis type 1 (NF-1) with a rosette-forming glioneuronal tumour (RGNT) in the lateral ventricle. The patient had been treated with radiotherapy and chemotherapy for a typical juvenile pilocytic astrocytoma of the hypothalamus seven years prior. MRI revealed a contrast-enhancing mass in the anterior horn of the left lateral ventricle. Histological examination demonstrated two distinct regions characterised by a rosette-forming neurocytic component and an astrocytic predominant component. Immunohistochemical studies showed glial fibrillary acidic protein and S-100 positivity in the astrocytic component and neuron-specific enolase was positive in the neurocytic cells. Although RGNT has been reported at other sites within the central nervous system, this report documents a previously undescribed lateral ventricular location of a rare RGNT in an asymptomatic patient with NF-1. © 2011 Elsevier Ltd. All rights reserved.-
dc.languageeng-
dc.relation.ispartofJournal of Clinical Neuroscience-
dc.subjectRosette-forming glioneuronal tumour-
dc.subjectNeurofibromatosis 1-
dc.subjectLateral ventricle-
dc.subjectRGNT-
dc.titleRosette-forming glioneuronal tumour of the lateral ventricle in a patient with neurofibromatosis 1-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.jocn.2011.12.013-
dc.identifier.pmid22613490-
dc.identifier.scopuseid_2-s2.0-84863111157-
dc.identifier.volume19-
dc.identifier.issue8-
dc.identifier.spage1180-
dc.identifier.epage1181-
dc.identifier.eissn1532-2653-
dc.identifier.isiWOS:000306500400031-
dc.identifier.issnl0967-5868-

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