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Conference Paper: Body Mass Index and its Association with Lumbar Disc Herniation and Sciatica: A Large-Scale, Population-Based Study
Title | Body Mass Index and its Association with Lumbar Disc Herniation and Sciatica: A Large-Scale, Population-Based Study |
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Authors | |
Issue Date | 2014 |
Publisher | Georg Thieme Verlag. The Journal's web site is located at http://www.thieme.com/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=1351&category_id=90&option=com_virtuemart&Itemid=53 |
Citation | World Forum for Spine Research (WFSR), Xi'an, China,15-17 May 2014. In Global Spine Journal, 2014, v. 4 n. Suppl. 1, p. S46, abstract no. PO.019 How to Cite? |
Abstract | Introduction
Elevated body mass index (BMI) or overweight and obesity are
pandemics. Lumbar disc herniation and sciatica occur in every
population and present severe socioeconomic consequences.
However, little is known regarding the role of BMI with
lumbar disc herniation and sciatica. As such, the following
large-scale study addressed the association of BMI, in particular
overweight and obesity, with disc herniation, its global
lumbar involvement and its implications with the development
of sciatica.
Materials and Methods
A cross-sectional study of 2,596 Southern Chinese (mean age:
42 years; 60% females) was conducted assessing T2-weighted
MRI, environmental and lifestyle factors, as well as clinical profiles of sciatica. On imaging, the presence of disc bulge/
extrusion (DBE) and other spinal phenotypes from L1-S1were
assessed. Disc degenerationwas assessed and graded based on
the Schneiderman et al criteria and summated of all levels to
produce a degenerative disc disease (DDD) score (potential
score range: 0-15). A total DBE (TDBE) score of L1-S1 was
calculated (potential score range: 0-10). Asian-modified BMI
values and categories of underweight, normal weight, overweight,
and obese were obtained for each subject.
Results
DBEwas noted in 46.3% of the subjects, mainly occurring at L4-
S1. The mean DDD and TDBE scores were 0.7 and 2.83,
respectively. Historical prevalence of sciatica was 44.6%,
with 17.9% reporting sciatica at the time of assessment. The
mean BMI was 22.9 kg/m2 (7.2% underweight, 47.9% normal
weight, 36.1% overweight, and 8.9% obese). Elevated DDD
scorewas significantly correlated with an elevated TDBE score
(r¼0.610; p< 0.001). TDBE score significantly increased with
elevated BMI categories (p< 0.001). Multivariate analyses
adjusting for covariates noted that elevated BMI was significantly
associated with DBE (normalweight [Ref]; underweight
OR: 0.71[95% CI: 0.49-1.03]; overweight OR: 1.26[95% CI:
1.04-1.52]; obese OR: 1.78[95% CI: 1.30-2.44]). TDBE score
(OR: 1.36; 95% CI: 1.15-1.60) and obesity (OR: 1.68; 95% CI:
1.25-2.24) were significantly related with sciatica. Worse
functional and disability scores were associated with sciatica
(p< 0.05).
Conclusion
Based on the largest population-based study to assess the role
of BMI and its association with disc herniation, this study
definitely noted that overweight and obesity significantly
increased the likelihood of having lumbar disc herniation,
its global severity, and the risk of developing sciatica.
Disclosure of Interest
None declared |
Description | Conference theme: The Intervertebral Disc - from Degeneration to Therapeutic Motion Preservation Poster presentation The abstract can be viewed at http://www.spineresearchforum.org/WFSR_2014_Thieme_AbstractBook_with_Cover.pdf |
Persistent Identifier | http://hdl.handle.net/10722/204388 |
ISSN | 2023 Impact Factor: 2.6 2023 SCImago Journal Rankings: 1.264 |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Samartzis, D | en_US |
dc.contributor.author | Karppinen, JI | en_US |
dc.contributor.author | Luk, KDK | en_US |
dc.contributor.author | Cheung, KMC | en_US |
dc.date.accessioned | 2014-09-19T22:41:29Z | - |
dc.date.available | 2014-09-19T22:41:29Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | World Forum for Spine Research (WFSR), Xi'an, China,15-17 May 2014. In Global Spine Journal, 2014, v. 4 n. Suppl. 1, p. S46, abstract no. PO.019 | en_US |
dc.identifier.issn | 2192-5682 | - |
dc.identifier.uri | http://hdl.handle.net/10722/204388 | - |
dc.description | Conference theme: The Intervertebral Disc - from Degeneration to Therapeutic Motion Preservation | - |
dc.description | Poster presentation | - |
dc.description | The abstract can be viewed at http://www.spineresearchforum.org/WFSR_2014_Thieme_AbstractBook_with_Cover.pdf | - |
dc.description.abstract | Introduction Elevated body mass index (BMI) or overweight and obesity are pandemics. Lumbar disc herniation and sciatica occur in every population and present severe socioeconomic consequences. However, little is known regarding the role of BMI with lumbar disc herniation and sciatica. As such, the following large-scale study addressed the association of BMI, in particular overweight and obesity, with disc herniation, its global lumbar involvement and its implications with the development of sciatica. Materials and Methods A cross-sectional study of 2,596 Southern Chinese (mean age: 42 years; 60% females) was conducted assessing T2-weighted MRI, environmental and lifestyle factors, as well as clinical profiles of sciatica. On imaging, the presence of disc bulge/ extrusion (DBE) and other spinal phenotypes from L1-S1were assessed. Disc degenerationwas assessed and graded based on the Schneiderman et al criteria and summated of all levels to produce a degenerative disc disease (DDD) score (potential score range: 0-15). A total DBE (TDBE) score of L1-S1 was calculated (potential score range: 0-10). Asian-modified BMI values and categories of underweight, normal weight, overweight, and obese were obtained for each subject. Results DBEwas noted in 46.3% of the subjects, mainly occurring at L4- S1. The mean DDD and TDBE scores were 0.7 and 2.83, respectively. Historical prevalence of sciatica was 44.6%, with 17.9% reporting sciatica at the time of assessment. The mean BMI was 22.9 kg/m2 (7.2% underweight, 47.9% normal weight, 36.1% overweight, and 8.9% obese). Elevated DDD scorewas significantly correlated with an elevated TDBE score (r¼0.610; p< 0.001). TDBE score significantly increased with elevated BMI categories (p< 0.001). Multivariate analyses adjusting for covariates noted that elevated BMI was significantly associated with DBE (normalweight [Ref]; underweight OR: 0.71[95% CI: 0.49-1.03]; overweight OR: 1.26[95% CI: 1.04-1.52]; obese OR: 1.78[95% CI: 1.30-2.44]). TDBE score (OR: 1.36; 95% CI: 1.15-1.60) and obesity (OR: 1.68; 95% CI: 1.25-2.24) were significantly related with sciatica. Worse functional and disability scores were associated with sciatica (p< 0.05). Conclusion Based on the largest population-based study to assess the role of BMI and its association with disc herniation, this study definitely noted that overweight and obesity significantly increased the likelihood of having lumbar disc herniation, its global severity, and the risk of developing sciatica. Disclosure of Interest None declared | - |
dc.language | eng | en_US |
dc.publisher | Georg Thieme Verlag. The Journal's web site is located at http://www.thieme.com/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=1351&category_id=90&option=com_virtuemart&Itemid=53 | - |
dc.relation.ispartof | Global Spine Journal | en_US |
dc.rights | Global Spine Journal. Copyright © Georg Thieme Verlag. | - |
dc.title | Body Mass Index and its Association with Lumbar Disc Herniation and Sciatica: A Large-Scale, Population-Based Study | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Samartzis, D: dspine@hku.hk | en_US |
dc.identifier.email | Luk, KDK: hrmoldk@hkucc.hku.hk | en_US |
dc.identifier.email | Cheung, KMC: cheungmc@hku.hk | en_US |
dc.identifier.authority | Samartzis, D=rp01430 | en_US |
dc.identifier.authority | Luk, KDK=rp00333 | en_US |
dc.identifier.hkuros | 238042 | en_US |
dc.identifier.volume | 4 | - |
dc.identifier.issue | Suppl. 1 | - |
dc.identifier.spage | S46, abstract no. PO.019 | - |
dc.identifier.epage | S46, abstract no. PO.019 | - |
dc.publisher.place | Germany | en_US |
dc.identifier.issnl | 2192-5682 | - |