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Conference Paper: Assessment of the Neurocentral Synchondrosis in Pediatric Spines and the 'Developmental' Etiology of Schmorl Nodes
Title | Assessment of the Neurocentral Synchondrosis in Pediatric Spines and the 'Developmental' Etiology of Schmorl Nodes |
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Authors | |
Issue Date | 2014 |
Publisher | Georg Thieme Verlag. The Journal's web site is located at http://www.thieme.com/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=1351&category_id=90&option=com_virtuemart&Itemid=53 |
Citation | World Forum for Spine Research (WFSR), Xi'an, China,15-17 May 2014. In Global Spine Journal, 2014, v. 4 n. Suppl. 1, p. S36-S37, abstract no. PO.002 How to Cite? |
Abstract | Introduction
Schmorl nodes of the thoracolumbar region have been associated
with the presence and severity of disc degeneration in
adults. The etiology of Schmorl nodes remains precarious;
however, a unique multilevel phenotype of “kissing” nodes
seems to suggest a developmental origin. The neurocentral
synchondrosis (NCS) are cartilaginous growth plates near the
neural arch ossification centers in a growing vertebrae that
may play a direct role in the development of endplate abnormalities,
such as Schmorl nodes. This study assessed the NCSin
pediatric spines to raise discussion of a developmental component
of Schmorl nodes.
Materials and Methods
A retrospective imaging study of pediatric patients at a single
institute assessed over a 5-year period (age range: 0-10 years)
was performed. Patients with spinal disorders (e.g., scoliosis)
were excluded. A total of 102 patients (57 males and 45
females) and a total of 113 sets of MRI images were reviewed.
The thoracolumbar regions (T12-S1) were evaluated. Sagittal
T1- and T2-weighted imageswere assessed for the presence or
absence of the NCS, defined as a hypointense vertical line
located between the vertebral body anteriorly and the posterior
arch. The presence of Schmorl nodes was also noted.
Results
NCS was noted in 46% of the MRIs. No statistically significant
difference in the disappearance of the NCS between different
age groups (p ¼ 0.063) or gender (p ¼ 0.706) was found. The NCS was noted to be completely fused at the midpoint of the
vertebrae. Indentation of the vertebral endplates resembling
Schmorl node at many of the rostral and caudal ends of the
unfused NCS were observed (Fig. 1). Conclusion
The significance of further characterizing the nature of NCS
closure may lie in potential associations with failure of
complete closure with endplate abnormalities, such as
Schmorl nodes. Our MRI study provides a foundation that a
development etiology of Schmorl nodes exists.
Disclosure of Interest
None declared |
Description | Conference theme: The Intervertebral Disc - from Degeneration to Therapeutic Motion Preservation Poster presentation The abstract can be viewed at http://www.spineresearchforum.org/WFSR_2014_Thieme_AbstractBook_with_Cover.pdf |
Persistent Identifier | http://hdl.handle.net/10722/203989 |
ISSN | 2023 Impact Factor: 2.6 2023 SCImago Journal Rankings: 1.264 |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Luk, KDK | en_US |
dc.contributor.author | Law, TK | en_US |
dc.contributor.author | Anthony, M | en_US |
dc.contributor.author | Samartzis, D | en_US |
dc.date.accessioned | 2014-09-19T19:48:26Z | - |
dc.date.available | 2014-09-19T19:48:26Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | World Forum for Spine Research (WFSR), Xi'an, China,15-17 May 2014. In Global Spine Journal, 2014, v. 4 n. Suppl. 1, p. S36-S37, abstract no. PO.002 | en_US |
dc.identifier.issn | 2192-5682 | - |
dc.identifier.uri | http://hdl.handle.net/10722/203989 | - |
dc.description | Conference theme: The Intervertebral Disc - from Degeneration to Therapeutic Motion Preservation | - |
dc.description | Poster presentation | - |
dc.description | The abstract can be viewed at http://www.spineresearchforum.org/WFSR_2014_Thieme_AbstractBook_with_Cover.pdf | - |
dc.description.abstract | Introduction Schmorl nodes of the thoracolumbar region have been associated with the presence and severity of disc degeneration in adults. The etiology of Schmorl nodes remains precarious; however, a unique multilevel phenotype of “kissing” nodes seems to suggest a developmental origin. The neurocentral synchondrosis (NCS) are cartilaginous growth plates near the neural arch ossification centers in a growing vertebrae that may play a direct role in the development of endplate abnormalities, such as Schmorl nodes. This study assessed the NCSin pediatric spines to raise discussion of a developmental component of Schmorl nodes. Materials and Methods A retrospective imaging study of pediatric patients at a single institute assessed over a 5-year period (age range: 0-10 years) was performed. Patients with spinal disorders (e.g., scoliosis) were excluded. A total of 102 patients (57 males and 45 females) and a total of 113 sets of MRI images were reviewed. The thoracolumbar regions (T12-S1) were evaluated. Sagittal T1- and T2-weighted imageswere assessed for the presence or absence of the NCS, defined as a hypointense vertical line located between the vertebral body anteriorly and the posterior arch. The presence of Schmorl nodes was also noted. Results NCS was noted in 46% of the MRIs. No statistically significant difference in the disappearance of the NCS between different age groups (p ¼ 0.063) or gender (p ¼ 0.706) was found. The NCS was noted to be completely fused at the midpoint of the vertebrae. Indentation of the vertebral endplates resembling Schmorl node at many of the rostral and caudal ends of the unfused NCS were observed (Fig. 1). Conclusion The significance of further characterizing the nature of NCS closure may lie in potential associations with failure of complete closure with endplate abnormalities, such as Schmorl nodes. Our MRI study provides a foundation that a development etiology of Schmorl nodes exists. Disclosure of Interest None declared | - |
dc.language | eng | en_US |
dc.publisher | Georg Thieme Verlag. The Journal's web site is located at http://www.thieme.com/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=1351&category_id=90&option=com_virtuemart&Itemid=53 | - |
dc.relation.ispartof | Global Spine Journal | en_US |
dc.rights | Global Spine Journal. Copyright © Georg Thieme Verlag. | - |
dc.title | Assessment of the Neurocentral Synchondrosis in Pediatric Spines and the 'Developmental' Etiology of Schmorl Nodes | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Luk, KDK: hrmoldk@hkucc.hku.hk | en_US |
dc.identifier.email | Anthony, M: anthonym@hku.hk | en_US |
dc.identifier.email | Samartzis, D: dspine@hku.hk | en_US |
dc.identifier.authority | Luk, KDK=rp00333 | en_US |
dc.identifier.authority | Anthony, M=rp01302 | en_US |
dc.identifier.authority | Samartzis, D=rp01430 | en_US |
dc.identifier.hkuros | 238037 | en_US |
dc.identifier.volume | 4 | - |
dc.identifier.issue | Suppl. 1 | - |
dc.identifier.spage | S36, abstract no. PO.002 | - |
dc.identifier.epage | S37, abstract no. PO.002 | - |
dc.publisher.place | Germany | en_US |
dc.identifier.issnl | 2192-5682 | - |