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Conference Paper: Chondroitinase ABC-I and -II linked chitosan microbeads increase neurtire length in CSPG-enriched astrocyte culture
| Title | Chondroitinase ABC-I and -II linked chitosan microbeads increase neurtire length in CSPG-enriched astrocyte culture |
|---|---|
| Authors | |
| Issue Date | 2014 |
| Citation | The 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Hong Kong, 14 June 2014. In Program Booklet, 2014, p. 49, poster no. 67 How to Cite? |
| Abstract | After spinal cord injury, axonal regrowth is often restricted due to upregulation of chondroitin sulfate proteoglycans (CSPGs) at the lesion site. Chondroitinase ABC I and II (recombinant ChABC-I & -II) cleave CS moieties of the PGs enhancing prospects of axonal regrowth through the lesion. We attempted to use glutaraldehyde to immobilize ChABC-I or-II separately on chitosan beads. Immobilized ChABC-I demonstrated CS-cleaving activity both in biochemical assay and in ... |
| Description | Poster Presentation - Theme 5: Neuroscience |
| Persistent Identifier | http://hdl.handle.net/10722/203875 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kwok, LF | en_US |
| dc.contributor.author | Shum, DKY | en_US |
| dc.date.accessioned | 2014-09-19T16:42:29Z | - |
| dc.date.available | 2014-09-19T16:42:29Z | - |
| dc.date.issued | 2014 | en_US |
| dc.identifier.citation | The 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Hong Kong, 14 June 2014. In Program Booklet, 2014, p. 49, poster no. 67 | en_US |
| dc.identifier.uri | http://hdl.handle.net/10722/203875 | - |
| dc.description | Poster Presentation - Theme 5: Neuroscience | - |
| dc.description.abstract | After spinal cord injury, axonal regrowth is often restricted due to upregulation of chondroitin sulfate proteoglycans (CSPGs) at the lesion site. Chondroitinase ABC I and II (recombinant ChABC-I & -II) cleave CS moieties of the PGs enhancing prospects of axonal regrowth through the lesion. We attempted to use glutaraldehyde to immobilize ChABC-I or-II separately on chitosan beads. Immobilized ChABC-I demonstrated CS-cleaving activity both in biochemical assay and in ... | - |
| dc.language | eng | en_US |
| dc.relation.ispartof | Hong Kong Inter-University 2014 Biochemistry Postgraduate Symposium | en_US |
| dc.title | Chondroitinase ABC-I and -II linked chitosan microbeads increase neurtire length in CSPG-enriched astrocyte culture | en_US |
| dc.type | Conference_Paper | en_US |
| dc.identifier.email | Kwok, LF: lamfungs@hku.hk | en_US |
| dc.identifier.email | Shum, DKY: shumdkhk@hkucc.hku.hk | en_US |
| dc.identifier.authority | Shum, DKY=rp00321 | en_US |
| dc.description.nature | postprint | - |
| dc.identifier.hkuros | 240409 | en_US |
| dc.identifier.spage | 49, poster no. 67 | - |
| dc.identifier.epage | 49, poster no. 67 | - |