File Download
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1016/j.jdent.2013.12.007
- Scopus: eid_2-s2.0-84897055146
- PMID: 24373856
- WOS: WOS:000333458400003
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: An ex vivo study of arrested primary teeth caries with silver diamine fluoride therapy
Title | An ex vivo study of arrested primary teeth caries with silver diamine fluoride therapy |
---|---|
Authors | |
Keywords | Silver diamine fluoride Dentine Collagen |
Issue Date | 2014 |
Publisher | Elsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jdent |
Citation | Journal of Dentistry, 2014, v. 42 n. 4, p. 395-402 How to Cite? |
Abstract | OBJECTIVES: This ex vivo study compared the physico-chemical structural differences between primary carious teeth biannually treated with silver diamine fluoride (SDF) and carious teeth without such treatment. METHOD: Twelve carious primary upper-central incisors were collected from 6-year-old children. Six teeth had arrested caries after 24-month biannual SDF applications and 6 had active caries when there was no topical fluoride treatment. The mineral density, elemental contents, surface morphology, and crystal characteristics were assessed by micro-computed tomography (micro-CT), energy-dispersive X-ray spectrometry (EDX), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). RESULTS: Micro-CT examination revealed a superficial opaque band approximately 150μm on the arrested cavitated dentinal lesion. This band was limited in the active carious lesion. EDX examination detected a higher intensity of calcium and phosphate of 150μm in the surface zone than in the inner zone, but this zone was restricted in the active cavitated dentinal lesion. SEM examination indicated that the collagens were protected from being exposed in the arrested cavitated dentinal lesion, but were exposed in the active cavitated dentinal lesion. TEM examination suggested that remineralised hydroxyapatites were well aligned in the arrested cavitated dentinal lesion, while those in the active cavitated dentinal lesion indicated a random apatite arrangement. CONCLUSIONS: A highly remineralised zone rich in calcium and phosphate was found on the arrested cavitated dentinal lesion of primary teeth with an SDF application. The collagens were protected from being exposed in the arrested cavitated dentinal lesion. CLINICAL SIGNIFICANCE: Clinical SDF application positively influences dentine remineralisation. |
Persistent Identifier | http://hdl.handle.net/10722/196262 |
ISSN | 2023 Impact Factor: 4.8 2023 SCImago Journal Rankings: 1.313 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Mei, L | - |
dc.contributor.author | Ito, L | - |
dc.contributor.author | Cao, Y | - |
dc.contributor.author | Lo, ECM | - |
dc.contributor.author | Li, QL | - |
dc.contributor.author | Chu, CH | - |
dc.date.accessioned | 2014-04-01T04:47:37Z | - |
dc.date.available | 2014-04-01T04:47:37Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | Journal of Dentistry, 2014, v. 42 n. 4, p. 395-402 | - |
dc.identifier.issn | 0300-5712 | - |
dc.identifier.uri | http://hdl.handle.net/10722/196262 | - |
dc.description.abstract | OBJECTIVES: This ex vivo study compared the physico-chemical structural differences between primary carious teeth biannually treated with silver diamine fluoride (SDF) and carious teeth without such treatment. METHOD: Twelve carious primary upper-central incisors were collected from 6-year-old children. Six teeth had arrested caries after 24-month biannual SDF applications and 6 had active caries when there was no topical fluoride treatment. The mineral density, elemental contents, surface morphology, and crystal characteristics were assessed by micro-computed tomography (micro-CT), energy-dispersive X-ray spectrometry (EDX), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). RESULTS: Micro-CT examination revealed a superficial opaque band approximately 150μm on the arrested cavitated dentinal lesion. This band was limited in the active carious lesion. EDX examination detected a higher intensity of calcium and phosphate of 150μm in the surface zone than in the inner zone, but this zone was restricted in the active cavitated dentinal lesion. SEM examination indicated that the collagens were protected from being exposed in the arrested cavitated dentinal lesion, but were exposed in the active cavitated dentinal lesion. TEM examination suggested that remineralised hydroxyapatites were well aligned in the arrested cavitated dentinal lesion, while those in the active cavitated dentinal lesion indicated a random apatite arrangement. CONCLUSIONS: A highly remineralised zone rich in calcium and phosphate was found on the arrested cavitated dentinal lesion of primary teeth with an SDF application. The collagens were protected from being exposed in the arrested cavitated dentinal lesion. CLINICAL SIGNIFICANCE: Clinical SDF application positively influences dentine remineralisation. | - |
dc.language | eng | - |
dc.publisher | Elsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jdent | - |
dc.relation.ispartof | Journal of Dentistry | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Silver diamine fluoride | - |
dc.subject | Dentine | - |
dc.subject | Collagen | - |
dc.title | An ex vivo study of arrested primary teeth caries with silver diamine fluoride therapy | - |
dc.type | Article | - |
dc.identifier.email | Mei, L: mei1123@hku.hk | - |
dc.identifier.email | Lo, ECM: hrdplcm@hkucc.hku.hk | - |
dc.identifier.email | Chu, CH: chchu@hku.hk | - |
dc.identifier.authority | Mei, L=rp01840 | - |
dc.identifier.authority | Lo, ECM=rp00015 | - |
dc.identifier.authority | Chu, CH=rp00022 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1016/j.jdent.2013.12.007 | - |
dc.identifier.pmid | 24373856 | - |
dc.identifier.scopus | eid_2-s2.0-84897055146 | - |
dc.identifier.hkuros | 228375 | - |
dc.identifier.hkuros | 228357 | - |
dc.identifier.volume | 42 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 395 | - |
dc.identifier.epage | 402 | - |
dc.identifier.isi | WOS:000333458400003 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 0300-5712 | - |