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Article: Efficacy and safety of Chinese herbal medicine for benign prostatic hyperplasia: systematic review of randomized controlled trials

TitleEfficacy and safety of Chinese herbal medicine for benign prostatic hyperplasia: systematic review of randomized controlled trials
Authors
KeywordsBenign prostatic hyperplasia (BPH)
Meta-analysis
Review
Traditional Chinese medicine
Issue Date2013
PublisherMedknow Publications. The Journal's web site is located at http://www.asiaandro.com
Citation
Asian Journal of Andrology, 2013, v. 15 n. 4, p. 471-482 How to Cite?
AbstractChinese herbal medicine is commonly used as a treatment for benign prostatic hyperplasia (BPH), but its efficacy and safety remain to be examined. To compare the efficacy and adverse events of Chinese herbal medicine alone or used adjuvantly with Western medications for BPH. Two independent reviewers searched the major electronic databases for randomized controlled trials comparing Chinese herbal medicine, either in single or adjuvant use with Western medication, with placebo or Western medication. Relevant journals and grey literature were also hand-searched. The outcome measures included changes in urological symptoms, urodynamic measures, prostate volume and adverse events. The frequency of commonly used herbs was also identified. Out of 13 922 identified citations of publications, 31 studies were included. Eleven studies with a Jadad score ≥3 were selected for meta-analysis. Chinese herbal medicine was superior to Western medication in improving quality of life and reducing prostate volume. The frequency of adverse events in Chinese herbal medicine was similar to that of placebo and less than that of Western medication. The evidence is too weak to support the efficacy of Chinese herbal medicine for BPH due to the poor methodological quality and small number of trials included. The commonly used herbs identified here should provide insights for future clinical practice and research. Larger randomized controlled trials of better quality are needed to truly evaluate the efficacy of Chinese herbal medicine.
Persistent Identifierhttp://hdl.handle.net/10722/195717
ISSN
2023 Impact Factor: 3.0
2023 SCImago Journal Rankings: 0.689
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorMa, CH-
dc.contributor.authorLin, WL-
dc.contributor.authorLui, SL-
dc.contributor.authorCai, X-
dc.contributor.authorWong, VT-
dc.contributor.authorZiea, E-
dc.contributor.authorZhang, Z-
dc.date.accessioned2014-03-07T04:32:36Z-
dc.date.available2014-03-07T04:32:36Z-
dc.date.issued2013-
dc.identifier.citationAsian Journal of Andrology, 2013, v. 15 n. 4, p. 471-482-
dc.identifier.issn1008-682X-
dc.identifier.urihttp://hdl.handle.net/10722/195717-
dc.description.abstractChinese herbal medicine is commonly used as a treatment for benign prostatic hyperplasia (BPH), but its efficacy and safety remain to be examined. To compare the efficacy and adverse events of Chinese herbal medicine alone or used adjuvantly with Western medications for BPH. Two independent reviewers searched the major electronic databases for randomized controlled trials comparing Chinese herbal medicine, either in single or adjuvant use with Western medication, with placebo or Western medication. Relevant journals and grey literature were also hand-searched. The outcome measures included changes in urological symptoms, urodynamic measures, prostate volume and adverse events. The frequency of commonly used herbs was also identified. Out of 13 922 identified citations of publications, 31 studies were included. Eleven studies with a Jadad score ≥3 were selected for meta-analysis. Chinese herbal medicine was superior to Western medication in improving quality of life and reducing prostate volume. The frequency of adverse events in Chinese herbal medicine was similar to that of placebo and less than that of Western medication. The evidence is too weak to support the efficacy of Chinese herbal medicine for BPH due to the poor methodological quality and small number of trials included. The commonly used herbs identified here should provide insights for future clinical practice and research. Larger randomized controlled trials of better quality are needed to truly evaluate the efficacy of Chinese herbal medicine.-
dc.languageeng-
dc.publisherMedknow Publications. The Journal's web site is located at http://www.asiaandro.com-
dc.relation.ispartofAsian Journal of Andrology-
dc.subjectBenign prostatic hyperplasia (BPH)-
dc.subjectMeta-analysis-
dc.subjectReview-
dc.subjectTraditional Chinese medicine-
dc.subject.meshDrugs, Chinese Herbal - administration and dosage - adverse effects-
dc.subject.meshProstatic Hyperplasia - drug therapy-
dc.subject.meshRandomized Controlled Trials as Topic-
dc.subject.meshTreatment Outcome-
dc.titleEfficacy and safety of Chinese herbal medicine for benign prostatic hyperplasia: systematic review of randomized controlled trials-
dc.typeArticle-
dc.identifier.emailCai, X: caixy@hkucc.hku.hk-
dc.identifier.emailZhang, Z: zhangzj@hkucc.hku.hk-
dc.identifier.authorityCai, X=rp01307-
dc.identifier.authorityZhang, Z=rp01297-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1038/aja.2012.173-
dc.identifier.pmid23728585-
dc.identifier.pmcidPMC3739225-
dc.identifier.scopuseid_2-s2.0-84880113613-
dc.identifier.hkuros228230-
dc.identifier.hkuros216759-
dc.identifier.volume15-
dc.identifier.issue4-
dc.identifier.spage471-
dc.identifier.epage482-
dc.identifier.isiWOS:000321190000012-
dc.publisher.placeIndia-
dc.identifier.issnl1008-682X-

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