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- Publisher Website: 10.1097/MNH.0b013e328326f3ca
- Scopus: eid_2-s2.0-67049113917
- PMID: 19374006
- WOS: WOS:000265560600004
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Article: Update on the podocyte
Title | Update on the podocyte |
---|---|
Authors | |
Issue Date | 2009 |
Citation | Current Opinion in Nephrology and Hypertension, 2009, v. 18 n. 3, p. 206-211 How to Cite? |
Abstract | PURPOSE OF REVIEW: The podocyte is a key cell in the selective filtering action of the glomerular capillary wall. Podocyte injury is of pathogenetic and prognostic significance in human glomerular disease; podocyte repair and regeneration are important therapeutic targets. This article will review recent advances in understanding the complex biology, structure and function of the podocyte and the related clinical implications. RECENT FINDINGS: Recent studies of podocytes in vivo and in vitro are described, highlighting clinically relevant observations and those that help us to understand the ways in which we may harness nature's own mechanisms to repair and/or renew these specialized glomerular cells. SUMMARY: Drugs that have beneficial effects on podocytes can improve our ability to treat important renal diseases, including diabetic nephropathy. Currently available agents can be harnessed in this way and the rapid progress in the study of podocytes is highlighting new therapeutic targets that can bring even more specificity. © 2009 Lippincott Williams & Wilkins. |
Persistent Identifier | http://hdl.handle.net/10722/195473 |
ISSN | 2023 Impact Factor: 2.2 2023 SCImago Journal Rankings: 0.959 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Mathieson, PW | - |
dc.date.accessioned | 2014-02-28T06:12:12Z | - |
dc.date.available | 2014-02-28T06:12:12Z | - |
dc.date.issued | 2009 | - |
dc.identifier.citation | Current Opinion in Nephrology and Hypertension, 2009, v. 18 n. 3, p. 206-211 | - |
dc.identifier.issn | 1062-4821 | - |
dc.identifier.uri | http://hdl.handle.net/10722/195473 | - |
dc.description.abstract | PURPOSE OF REVIEW: The podocyte is a key cell in the selective filtering action of the glomerular capillary wall. Podocyte injury is of pathogenetic and prognostic significance in human glomerular disease; podocyte repair and regeneration are important therapeutic targets. This article will review recent advances in understanding the complex biology, structure and function of the podocyte and the related clinical implications. RECENT FINDINGS: Recent studies of podocytes in vivo and in vitro are described, highlighting clinically relevant observations and those that help us to understand the ways in which we may harness nature's own mechanisms to repair and/or renew these specialized glomerular cells. SUMMARY: Drugs that have beneficial effects on podocytes can improve our ability to treat important renal diseases, including diabetic nephropathy. Currently available agents can be harnessed in this way and the rapid progress in the study of podocytes is highlighting new therapeutic targets that can bring even more specificity. © 2009 Lippincott Williams & Wilkins. | - |
dc.language | eng | - |
dc.relation.ispartof | Current Opinion in Nephrology and Hypertension | - |
dc.title | Update on the podocyte | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1097/MNH.0b013e328326f3ca | - |
dc.identifier.pmid | 19374006 | - |
dc.identifier.scopus | eid_2-s2.0-67049113917 | - |
dc.identifier.volume | 18 | - |
dc.identifier.issue | 3 | - |
dc.identifier.spage | 206 | - |
dc.identifier.epage | 211 | - |
dc.identifier.isi | WOS:000265560600004 | - |
dc.identifier.issnl | 1062-4821 | - |