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- Publisher Website: 10.1016/S0167-7799(02)00031-8
- Scopus: eid_2-s2.0-0037309660
- PMID: 12573851
- WOS: WOS:000181154900002
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Article: The new role of SAGE in gene discovery
Title | The new role of SAGE in gene discovery |
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Authors | |
Issue Date | 2003 |
Citation | Trends in Biotechnology, 2003, v. 21 n. 2, p. 55-57 How to Cite? |
Abstract | The sequencing of the human genome has led to in silico predictions of far fewer genes than anticipated. Recent studies using serial analysis of gene expression have cast doubt on this finding. One study predicts the presence of many unidentified low abundance transcripts, whereas two others have mapped unique tags to previously unpredicted exons. Genome and transcriptome complexity is thus greater than predicted and many of the missing genes are probably expressed in low copy numbers or only in early embryonic tissues. |
Persistent Identifier | http://hdl.handle.net/10722/195163 |
ISSN | 2023 Impact Factor: 14.3 2023 SCImago Journal Rankings: 2.536 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Boheler, KR | - |
dc.contributor.author | Stern, MD | - |
dc.date.accessioned | 2014-02-25T01:40:15Z | - |
dc.date.available | 2014-02-25T01:40:15Z | - |
dc.date.issued | 2003 | - |
dc.identifier.citation | Trends in Biotechnology, 2003, v. 21 n. 2, p. 55-57 | - |
dc.identifier.issn | 0167-7799 | - |
dc.identifier.uri | http://hdl.handle.net/10722/195163 | - |
dc.description.abstract | The sequencing of the human genome has led to in silico predictions of far fewer genes than anticipated. Recent studies using serial analysis of gene expression have cast doubt on this finding. One study predicts the presence of many unidentified low abundance transcripts, whereas two others have mapped unique tags to previously unpredicted exons. Genome and transcriptome complexity is thus greater than predicted and many of the missing genes are probably expressed in low copy numbers or only in early embryonic tissues. | - |
dc.language | eng | - |
dc.relation.ispartof | Trends in Biotechnology | - |
dc.title | The new role of SAGE in gene discovery | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/S0167-7799(02)00031-8 | - |
dc.identifier.pmid | 12573851 | - |
dc.identifier.scopus | eid_2-s2.0-0037309660 | - |
dc.identifier.volume | 21 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 55 | - |
dc.identifier.epage | 57 | - |
dc.identifier.isi | WOS:000181154900002 | - |
dc.identifier.issnl | 1879-3096 | - |