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Book Chapter: Exogenous nerve growth factor stimulates choline acetyltransferase activity in basal forebrain of axotomized and aged rats
| Title | Exogenous nerve growth factor stimulates choline acetyltransferase activity in basal forebrain of axotomized and aged rats |
|---|---|
| Authors | |
| Issue Date | 1989 |
| Publisher | Springer |
| Citation | Exogenous nerve growth factor stimulates choline acetyltransferase activity in basal forebrain of axotomized and aged rats. In Meyer, EM, Simpkins, JW, and Yamamoto, J (Eds.), Novel Approaches to the Treatment of Alzheimer’s Disease, v. 36, p. 103-115. US: Springer, 1989 How to Cite? |
| Abstract | Nerve growth factor (NGF) is physiologically critical for the survival and normal development of sympathetic and spinal sensory neurons, and for their maintenance in the adult (1,2). NGF has been found to have a similar role in the mammalian central nervous system (CNS) (3). NGF was first implicated in CNS function when Schwab et al. (4) found specific retrograde transport of exogenous NGF from cerebral and hippocampal cortices to neuronal cell bodies in the rat basal forebrain. NGF is now known to be present and produced in the CNS, and is in largest amount in the cortex and hippocampus, the target tissues for neurons in the basal forebrain (3). |
| Persistent Identifier | http://hdl.handle.net/10722/194887 |
| ISBN | |
| ISSN |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Williams, LP | - |
| dc.contributor.author | Jodelis, KS | - |
| dc.contributor.author | Donale, MR | - |
| dc.contributor.author | Yip, HKF | - |
| dc.date.accessioned | 2014-02-17T06:27:59Z | - |
| dc.date.available | 2014-02-17T06:27:59Z | - |
| dc.date.issued | 1989 | - |
| dc.identifier.citation | Exogenous nerve growth factor stimulates choline acetyltransferase activity in basal forebrain of axotomized and aged rats. In Meyer, EM, Simpkins, JW, and Yamamoto, J (Eds.), Novel Approaches to the Treatment of Alzheimer’s Disease, v. 36, p. 103-115. US: Springer, 1989 | - |
| dc.identifier.isbn | 978-1-4684-5729-2 | - |
| dc.identifier.issn | 0099-6246 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/194887 | - |
| dc.description.abstract | Nerve growth factor (NGF) is physiologically critical for the survival and normal development of sympathetic and spinal sensory neurons, and for their maintenance in the adult (1,2). NGF has been found to have a similar role in the mammalian central nervous system (CNS) (3). NGF was first implicated in CNS function when Schwab et al. (4) found specific retrograde transport of exogenous NGF from cerebral and hippocampal cortices to neuronal cell bodies in the rat basal forebrain. NGF is now known to be present and produced in the CNS, and is in largest amount in the cortex and hippocampus, the target tissues for neurons in the basal forebrain (3). | - |
| dc.language | eng | - |
| dc.publisher | Springer | - |
| dc.relation.ispartof | Novel Approaches to the Treatment of Alzheimer’s Disease | - |
| dc.title | Exogenous nerve growth factor stimulates choline acetyltransferase activity in basal forebrain of axotomized and aged rats | en_US |
| dc.type | Book_Chapter | en_US |
| dc.identifier.email | Yip, HKF: hkfyip@hku.hk, hkfyip@hkusua.hku.hk | - |
| dc.description.nature | link_to_subscribed_fulltext | - |
| dc.identifier.doi | 10.1007/978-1-4684-5727-8_10 | - |
| dc.identifier.volume | 36 | - |
| dc.identifier.spage | 103 | - |
| dc.identifier.epage | 115 | - |
| dc.publisher.place | US | - |
| dc.identifier.issnl | 0099-6246 | - |