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- Publisher Website: 10.3748/wjg.v12.i2.199
- Scopus: eid_2-s2.0-33644787381
- PMID: 16482618
- WOS: WOS:000239946500004
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Article: E-cadherin in gastric cancer
Title | E-cadherin in gastric cancer |
---|---|
Authors | |
Keywords | E-cadherin Gastric cancer |
Issue Date | 2006 |
Publisher | Baishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htm |
Citation | World Journal of Gastroenterology, 2006, v. 12 n. 2, p. 199-203 How to Cite? |
Abstract | Cadherin is an adhesion molecule and a superfamily of calcium-mediated membrane glycoproteins. E-cadherin is the prototype of the class E-cadherin that links to catenins to form the cytoskeleton. Recent evidence has shown that E-cadherin not only acts as an adhesive, but also plays important roles in growth development and carcinogenesis. It has been recently viewed as an invasion as well as a growth suppressor gene. This review summarizes the recent discoveries on E-cadherin and its role in gastric cancer. In particular, our work on E-cadherin in gastric cancer, including its relation with Helicobacter pylori and clinical applications, are described in detail. |
Persistent Identifier | http://hdl.handle.net/10722/194550 |
ISSN | 2023 Impact Factor: 4.3 2023 SCImago Journal Rankings: 1.063 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Chan, AOO | - |
dc.date.accessioned | 2014-02-11T07:57:30Z | - |
dc.date.available | 2014-02-11T07:57:30Z | - |
dc.date.issued | 2006 | - |
dc.identifier.citation | World Journal of Gastroenterology, 2006, v. 12 n. 2, p. 199-203 | - |
dc.identifier.issn | 1007-9327 | - |
dc.identifier.uri | http://hdl.handle.net/10722/194550 | - |
dc.description.abstract | Cadherin is an adhesion molecule and a superfamily of calcium-mediated membrane glycoproteins. E-cadherin is the prototype of the class E-cadherin that links to catenins to form the cytoskeleton. Recent evidence has shown that E-cadherin not only acts as an adhesive, but also plays important roles in growth development and carcinogenesis. It has been recently viewed as an invasion as well as a growth suppressor gene. This review summarizes the recent discoveries on E-cadherin and its role in gastric cancer. In particular, our work on E-cadherin in gastric cancer, including its relation with Helicobacter pylori and clinical applications, are described in detail. | - |
dc.language | eng | - |
dc.publisher | Baishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htm | - |
dc.relation.ispartof | World Journal of Gastroenterology | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | E-cadherin | - |
dc.subject | Gastric cancer | - |
dc.subject.mesh | Cadherins - analysis - genetics - physiology | - |
dc.subject.mesh | Genes, Tumor Suppressor | - |
dc.subject.mesh | Helicobacter Infections - complications | - |
dc.subject.mesh | Helicobacter pylori | - |
dc.subject.mesh | Stomach Neoplasms - etiology - genetics | - |
dc.title | E-cadherin in gastric cancer | en_US |
dc.type | Article | en_US |
dc.identifier.email | Chan, AOO: aoochan@hku.hk | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.3748/wjg.v12.i2.199 | - |
dc.identifier.pmid | 16482618 | - |
dc.identifier.pmcid | PMC4066027 | - |
dc.identifier.scopus | eid_2-s2.0-33644787381 | - |
dc.identifier.hkuros | 122750 | - |
dc.identifier.volume | 12 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 199 | - |
dc.identifier.epage | 203 | - |
dc.identifier.isi | WOS:000239946500004 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 1007-9327 | - |