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- Publisher Website: 10.1186/1475-2840-12-133
- Scopus: eid_2-s2.0-84883861274
- PMID: 24041262
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Article: Susceptibility to myocardial ischemia reperfusion injury at early stage of type 1 diabetes in rats
Title | Susceptibility to myocardial ischemia reperfusion injury at early stage of type 1 diabetes in rats |
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Authors | |
Keywords | Ischemia reperfusion injury Diabetes mellitus Infarct size |
Issue Date | 2013 |
Publisher | BioMed Central Ltd. The Journal's web site is located at http://www.cardiab.com/ |
Citation | Cardiovascular Diabetology, 2013, v. 12 n. 1, p. article no. 133 How to Cite? |
Abstract | Large body of evidences accumulated in clinical and epidemiological studies indicate that hearts of diabetic subjects are more sensitive to ischemia reperfusion injury (IRI), which results in a higher rate of mortality at post-operation than that of non-diabetes. However, experimental results are equivocal and point to either increased or decreased susceptibility of the diabetic hearts to IRI, especially at the early stage of the disease. The present study was designed to test the hypothesis that the duration/severity of the indexed ischemia is a major determinant of the vulnerability to myocardial IRI at early stage of diabetes. |
Persistent Identifier | http://hdl.handle.net/10722/193160 |
ISSN | 2023 Impact Factor: 8.5 2023 SCImago Journal Rankings: 2.621 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Li, H | en_US |
dc.contributor.author | Liu, Z | en_US |
dc.contributor.author | Wang, JJ | en_US |
dc.contributor.author | Wong, GT | en_US |
dc.contributor.author | Cheung, CW | en_US |
dc.contributor.author | Zhang, L | en_US |
dc.contributor.author | Chen, C | en_US |
dc.contributor.author | Xia, Z | en_US |
dc.contributor.author | Irwin, MG | en_US |
dc.date.accessioned | 2013-12-20T02:25:44Z | - |
dc.date.available | 2013-12-20T02:25:44Z | - |
dc.date.issued | 2013 | en_US |
dc.identifier.citation | Cardiovascular Diabetology, 2013, v. 12 n. 1, p. article no. 133 | en_US |
dc.identifier.issn | 1475-2840 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/193160 | - |
dc.description.abstract | Large body of evidences accumulated in clinical and epidemiological studies indicate that hearts of diabetic subjects are more sensitive to ischemia reperfusion injury (IRI), which results in a higher rate of mortality at post-operation than that of non-diabetes. However, experimental results are equivocal and point to either increased or decreased susceptibility of the diabetic hearts to IRI, especially at the early stage of the disease. The present study was designed to test the hypothesis that the duration/severity of the indexed ischemia is a major determinant of the vulnerability to myocardial IRI at early stage of diabetes. | - |
dc.language | eng | en_US |
dc.publisher | BioMed Central Ltd. The Journal's web site is located at http://www.cardiab.com/ | - |
dc.relation.ispartof | Cardiovascular Diabetology | en_US |
dc.rights | Cardiovascular Diabetology. Copyright © BioMed Central Ltd. | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Ischemia reperfusion injury | - |
dc.subject | Diabetes mellitus | - |
dc.subject | Infarct size | - |
dc.title | Susceptibility to myocardial ischemia reperfusion injury at early stage of type 1 diabetes in rats | en_US |
dc.type | Article | en_US |
dc.identifier.email | Wang, JJ: junwen@hku.hk | en_US |
dc.identifier.email | Wong, GT: gordon@hku.hk | en_US |
dc.identifier.email | Xia, Z: zyxia@hku.hk | en_US |
dc.identifier.email | Irwin, MG: mgirwin@hku.hk | - |
dc.identifier.authority | Wang, JJ=rp00280 | en_US |
dc.identifier.authority | Wong, GT=rp00523 | en_US |
dc.identifier.authority | Xia, Z=rp00532 | en_US |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1186/1475-2840-12-133 | en_US |
dc.identifier.pmid | 24041262 | - |
dc.identifier.pmcid | PMC3847499 | - |
dc.identifier.scopus | eid_2-s2.0-84883861274 | - |
dc.identifier.hkuros | 226969 | en_US |
dc.identifier.hkuros | 227645 | - |
dc.identifier.volume | 12 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.spage | article no. 133 | en_US |
dc.identifier.epage | article no. 133 | en_US |
dc.identifier.isi | WOS:000324515800001 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 1475-2840 | - |