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Conference Paper: Metabolic effects of secretin

TitleMetabolic effects of secretin
Authors
KeywordsSecretin (Sct)
Metabolic role
Food intake
Glucose homeostasis
Fatty acid metabolism
Energy homeostasis
Issue Date2013
PublisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygcen
Citation
The International Symposium on Comparative Endocrinology and Stress Physiology (CESP) 2012 and the 7th Asia and Oceania Society for Comparative Endocrinology (AOSCE) Congress, (CESP) Kerala, India and (AOSCE) Kuala Lumpur, Malaysia, 2012. In General and Comparative Endocrinology, 2013, v. 181, p. 18-24 How to Cite?
AbstractSecretin (Sct), traditionally a gastrointestinal hormone backed by a century long research, is now beginning to be recognized also as a neuroactive peptide. Substantiation by recent evidence on the functional role of Sct in various regions of the brain, especially on its potential neurosecretion from the posterior pituitary, has revealed Sct’s physiological actions in regulating water homeostasis. Recent advances in understanding the functional roles of central and peripheral Sct has been made possible by the development of Sct and Sct receptor (SctR) knockout animal models which have led to novel approaches in research on the physiology of this brain-gut peptide. While research on the role of Sct in appetite regulation and fatty acid metabolism has been initiated recently, its role in glucose homeostasis is unclear. This review focuses mainly on the metabolic role of Sct by discussing data from the last century and recent discoveries, with emphasis on the need for revisiting and elucidating the role of Sct in metabolism and energy homeostasis.
DescriptionCombined Special Issues: The International Symposium on Comparative Endocrinology and Stress Physiology (CESP) 2012 and the 7th Asia and Oceania Society for Comparative Endocrinology (AOSCE) Congress
Persistent Identifierhttp://hdl.handle.net/10722/190369
ISSN
2023 Impact Factor: 2.1
2023 SCImago Journal Rankings: 0.616
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorSekar, R-
dc.contributor.authorChow, BKC-
dc.date.accessioned2013-09-17T15:21:36Z-
dc.date.available2013-09-17T15:21:36Z-
dc.date.issued2013-
dc.identifier.citationThe International Symposium on Comparative Endocrinology and Stress Physiology (CESP) 2012 and the 7th Asia and Oceania Society for Comparative Endocrinology (AOSCE) Congress, (CESP) Kerala, India and (AOSCE) Kuala Lumpur, Malaysia, 2012. In General and Comparative Endocrinology, 2013, v. 181, p. 18-24-
dc.identifier.issn0016-6480-
dc.identifier.urihttp://hdl.handle.net/10722/190369-
dc.descriptionCombined Special Issues: The International Symposium on Comparative Endocrinology and Stress Physiology (CESP) 2012 and the 7th Asia and Oceania Society for Comparative Endocrinology (AOSCE) Congress-
dc.description.abstractSecretin (Sct), traditionally a gastrointestinal hormone backed by a century long research, is now beginning to be recognized also as a neuroactive peptide. Substantiation by recent evidence on the functional role of Sct in various regions of the brain, especially on its potential neurosecretion from the posterior pituitary, has revealed Sct’s physiological actions in regulating water homeostasis. Recent advances in understanding the functional roles of central and peripheral Sct has been made possible by the development of Sct and Sct receptor (SctR) knockout animal models which have led to novel approaches in research on the physiology of this brain-gut peptide. While research on the role of Sct in appetite regulation and fatty acid metabolism has been initiated recently, its role in glucose homeostasis is unclear. This review focuses mainly on the metabolic role of Sct by discussing data from the last century and recent discoveries, with emphasis on the need for revisiting and elucidating the role of Sct in metabolism and energy homeostasis.-
dc.languageeng-
dc.publisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygcen-
dc.relation.ispartofGeneral and Comparative Endocrinology-
dc.rightsNOTICE: this is the author’s version of a work that was accepted for publication in General and Comparative Endocrinology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in General and Comparative Endocrinology, 2013, v. 181, p. 18-24. DOI: 10.1016/j.ygcen.2012.11.017-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectSecretin (Sct)-
dc.subjectMetabolic role-
dc.subjectFood intake-
dc.subjectGlucose homeostasis-
dc.subjectFatty acid metabolism-
dc.subjectEnergy homeostasis-
dc.titleMetabolic effects of secretin-
dc.typeConference_Paper-
dc.identifier.emailChow, BKC: bkcc@hku.hk-
dc.identifier.authorityChow, BKC=rp00681-
dc.description.naturepostprint-
dc.identifier.doi10.1016/j.ygcen.2012.11.017-
dc.identifier.pmid23246720-
dc.identifier.scopuseid_2-s2.0-84873055573-
dc.identifier.hkuros222852-
dc.identifier.hkuros249447-
dc.identifier.volume181-
dc.identifier.spage18-
dc.identifier.epage24-
dc.identifier.isiWOS:000314906200005-
dc.publisher.placeUnited States-
dc.identifier.issnl0016-6480-

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