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- Publisher Website: 10.1017/S1041610213000161
- Scopus: eid_2-s2.0-84885455666
- PMID: 23544873
- WOS: WOS:000321262200010
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Article: Cognitive predictors for five-year conversion to dementia in community-dwelling Chinese older adults
Title | Cognitive predictors for five-year conversion to dementia in community-dwelling Chinese older adults |
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Authors | |
Keywords | cognitive predictors dementia mild cognitive impairment |
Issue Date | 2013 |
Publisher | Cambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=IPG |
Citation | International Psychogeriatrics: the official journal of the Interntional Psychogeriatric Association, 2013, v. 25 n. 7, p. 1125-1134 How to Cite? |
Abstract | BACKGROUND: This study evaluates which cognitive measure is best for predicting incident dementia in a population-based random sample of Chinese older adults without dementia over a five-year period. METHODS: A total of 787 community-dwelling Chinese older adults without dementia in Hong Kong were assessed at baseline (T0), at two years (T1), and at five years (T2). RESULTS: The annual conversion rate to dementia was 1.6% and 6.3% for baseline normal participants and baseline mild cognitive impairment (MCI) participants, respectively. The Cantonese version of Mini-mental State Examination (CMMSE) scores declined significantly over time. In participants who progressed to dementia, Category Verbal Fluency Test (CVFT) scores dropped significantly from T0 to T1. A 1-SD drop of either CMMSE or CVFT in two years predicted dementia at five years with 91.5% sensitivity and 62.0% specificity. A stable CMMSE and CVFT at two years predicted a 91% chance of not progressing to clinical dementia at five years. CONCLUSION: In this community sample of Chinese older adults, a decline in cognitive screening tests in short term (two years) offered useful information in predicting dementia conversion over a longer period. |
Persistent Identifier | http://hdl.handle.net/10722/189377 |
ISSN | 2023 Impact Factor: 4.6 2023 SCImago Journal Rankings: 1.121 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Wong, CHY | en_US |
dc.contributor.author | Leung, GTY | en_US |
dc.contributor.author | Fung, AWT | en_US |
dc.contributor.author | Chan, WC | en_US |
dc.contributor.author | Lam, LCW | en_US |
dc.date.accessioned | 2013-09-17T14:38:06Z | - |
dc.date.available | 2013-09-17T14:38:06Z | - |
dc.date.issued | 2013 | en_US |
dc.identifier.citation | International Psychogeriatrics: the official journal of the Interntional Psychogeriatric Association, 2013, v. 25 n. 7, p. 1125-1134 | en_US |
dc.identifier.issn | 1041-6102 | - |
dc.identifier.uri | http://hdl.handle.net/10722/189377 | - |
dc.description.abstract | BACKGROUND: This study evaluates which cognitive measure is best for predicting incident dementia in a population-based random sample of Chinese older adults without dementia over a five-year period. METHODS: A total of 787 community-dwelling Chinese older adults without dementia in Hong Kong were assessed at baseline (T0), at two years (T1), and at five years (T2). RESULTS: The annual conversion rate to dementia was 1.6% and 6.3% for baseline normal participants and baseline mild cognitive impairment (MCI) participants, respectively. The Cantonese version of Mini-mental State Examination (CMMSE) scores declined significantly over time. In participants who progressed to dementia, Category Verbal Fluency Test (CVFT) scores dropped significantly from T0 to T1. A 1-SD drop of either CMMSE or CVFT in two years predicted dementia at five years with 91.5% sensitivity and 62.0% specificity. A stable CMMSE and CVFT at two years predicted a 91% chance of not progressing to clinical dementia at five years. CONCLUSION: In this community sample of Chinese older adults, a decline in cognitive screening tests in short term (two years) offered useful information in predicting dementia conversion over a longer period. | - |
dc.language | eng | en_US |
dc.publisher | Cambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=IPG | - |
dc.relation.ispartof | International Psychogeriatrics: the official journal of the Interntional Psychogeriatric Association | en_US |
dc.rights | International Psychogeriatrics: the official journal of the Interntional Psychogeriatric Association. Copyright © Cambridge University Press. | - |
dc.subject | cognitive predictors | - |
dc.subject | dementia | - |
dc.subject | mild cognitive impairment | - |
dc.subject.mesh | Asian Continental Ancestry Group - psychology | - |
dc.subject.mesh | Dementia - diagnosis - psychology | - |
dc.subject.mesh | Geriatric Assessment - methods - statistics and numerical data | - |
dc.subject.mesh | Mental Status Schedule | - |
dc.subject.mesh | Mild Cognitive Impairment - diagnosis | - |
dc.title | Cognitive predictors for five-year conversion to dementia in community-dwelling Chinese older adults | en_US |
dc.type | Article | en_US |
dc.identifier.email | Chan, WC: waicchan@hku.hk | en_US |
dc.identifier.authority | Chan, WC=rp01687 | en_US |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1017/S1041610213000161 | - |
dc.identifier.pmid | 23544873 | - |
dc.identifier.scopus | eid_2-s2.0-84885455666 | - |
dc.identifier.hkuros | 223357 | en_US |
dc.identifier.hkuros | 232518 | - |
dc.identifier.volume | 25 | en_US |
dc.identifier.issue | 7 | - |
dc.identifier.spage | 1125 | en_US |
dc.identifier.epage | 1134 | en_US |
dc.identifier.isi | WOS:000321262200010 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 1041-6102 | - |