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Conference Paper: Developing novel fluorescent probe for peroxynitrite: implication for understanding the roles of peroxynitrite and drug discovery in cerebral ischemia reperfusion injury
Title | Developing novel fluorescent probe for peroxynitrite: implication for understanding the roles of peroxynitrite and drug discovery in cerebral ischemia reperfusion injury |
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Authors | |
Issue Date | 2013 |
Publisher | The Conference. |
Citation | The 41th Annual ISOTT Conference & EPR 2013 Conference, Hanover, NH., 22-28 June 2013. How to Cite? |
Abstract | STUDY GOAL: Peroxynitrite (ONOO‐) is a cytotoxic factor. As its short lifetime, ONOO‐ is hard to be detected in biological systems. This study aims to develop novel probe for detecting ONOO‐ and understand the roles of ONOO‐ in ischemic brains and drug discovery ABSTRACT: MitoPN‐1 was found to be a ONOO‐ specific probe with no toxicity. With MitoPN‐1, we studied the roles of ONOO‐ in hypoxic neuronal cells in vitro and MCAO … |
Description | Session 7 - Oral Presentations |
Persistent Identifier | http://hdl.handle.net/10722/187938 |
DC Field | Value | Language |
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dc.contributor.author | Shen, J | en_US |
dc.contributor.author | Chen, X | - |
dc.contributor.author | Xu, M | - |
dc.contributor.author | Gu, Y | - |
dc.contributor.author | Yang, D | - |
dc.date.accessioned | 2013-08-21T07:23:13Z | - |
dc.date.available | 2013-08-21T07:23:13Z | - |
dc.date.issued | 2013 | en_US |
dc.identifier.citation | The 41th Annual ISOTT Conference & EPR 2013 Conference, Hanover, NH., 22-28 June 2013. | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/187938 | - |
dc.description | Session 7 - Oral Presentations | - |
dc.description.abstract | STUDY GOAL: Peroxynitrite (ONOO‐) is a cytotoxic factor. As its short lifetime, ONOO‐ is hard to be detected in biological systems. This study aims to develop novel probe for detecting ONOO‐ and understand the roles of ONOO‐ in ischemic brains and drug discovery ABSTRACT: MitoPN‐1 was found to be a ONOO‐ specific probe with no toxicity. With MitoPN‐1, we studied the roles of ONOO‐ in hypoxic neuronal cells in vitro and MCAO … | - |
dc.language | eng | en_US |
dc.publisher | The Conference. | - |
dc.relation.ispartof | ISOTT / EPR 2013 | en_US |
dc.title | Developing novel fluorescent probe for peroxynitrite: implication for understanding the roles of peroxynitrite and drug discovery in cerebral ischemia reperfusion injury | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Shen, J: shenjg@hku.hk | en_US |
dc.identifier.email | Yang, D: yangdan@hku.hk | - |
dc.identifier.authority | Shen, J=rp00487 | en_US |
dc.description.nature | postprint | - |
dc.identifier.hkuros | 216842 | en_US |
dc.publisher.place | United States | - |