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Book Chapter: Metal Complexes in the Treatment of Tropical Diseases: Malaria, Trypanosomiasis, and Leishmaniasis

TitleMetal Complexes in the Treatment of Tropical Diseases: Malaria, Trypanosomiasis, and Leishmaniasis
Authors
Wang, XSun, H
KeywordsAntimony
Chloroquine
Ferrocene
Gold
Leishmaniasis
Issue Date2013
PublisherElsevier
Citation
Metal Complexes in the Treatment of Tropical Diseases: Malaria, Trypanosomiasis, and Leishmaniasis. In Pecoraro, VL & Hambley, TW (Eds.), Comprehensive inorganic chemistry II: from elements to applications (2nd ed.), v. 3, p. 975-986. Amsterdam: Elsevier, 2013 How to Cite?
DOI: http://dx.doi.org/10.1016/B978-0-08-097774-4.00339-9
AbstractParasitic diseases such as malaria, trypanosomiasis, and leishmaniasis are major health problems in the tropical area. Most clinically used drugs are decades old and suffered from severe side effects, limited efficacy, and emergence of drug resistance. As an alternative, the application of metal complexes as potential antiparasitic agents appears to be a promising approach. In this chapter, the advantages of metal complexes for the potential treatment of parasitic diseases are described. Further study on the mechanism of action of these compounds may facilitate the development of new metallodrugs with higher efficacy.
DescriptionV. 3 title: Bioinorganic Fundamentals and Applications: Metals in Natural Living Systems and Metals in Toxicology and Medicine
Persistent Identifierhttp://hdl.handle.net/10722/187411
ISBN
9780080965291

 

DC FieldValueLanguage
dc.contributor.authorWang, Xen_US
dc.contributor.authorSun, Hen_US
dc.date.accessioned2013-08-20T12:42:40Z-
dc.date.available2013-08-20T12:42:40Z-
dc.date.issued2013en_US
dc.identifier.citationMetal Complexes in the Treatment of Tropical Diseases: Malaria, Trypanosomiasis, and Leishmaniasis. In Pecoraro, VL & Hambley, TW (Eds.), Comprehensive inorganic chemistry II: from elements to applications (2nd ed.), v. 3, p. 975-986. Amsterdam: Elsevier, 2013en_US
dc.identifier.isbn9780080965291-
dc.identifier.urihttp://hdl.handle.net/10722/187411-
dc.descriptionV. 3 title: Bioinorganic Fundamentals and Applications: Metals in Natural Living Systems and Metals in Toxicology and Medicine-
dc.description.abstractParasitic diseases such as malaria, trypanosomiasis, and leishmaniasis are major health problems in the tropical area. Most clinically used drugs are decades old and suffered from severe side effects, limited efficacy, and emergence of drug resistance. As an alternative, the application of metal complexes as potential antiparasitic agents appears to be a promising approach. In this chapter, the advantages of metal complexes for the potential treatment of parasitic diseases are described. Further study on the mechanism of action of these compounds may facilitate the development of new metallodrugs with higher efficacy.-
dc.languageengen_US
dc.publisherElsevieren_US
dc.relation.ispartofComprehensive inorganic chemistry II: from elements to applications (2nd ed.)-
dc.subjectAntimony-
dc.subjectChloroquine-
dc.subjectFerrocene-
dc.subjectGold-
dc.subjectLeishmaniasis-
dc.titleMetal Complexes in the Treatment of Tropical Diseases: Malaria, Trypanosomiasis, and Leishmaniasisen_US
dc.typeBook_Chapteren_US
dc.identifier.emailSun, H: hsun@hku.hken_US
dc.identifier.authoritySun, H=rp00777en_US
dc.identifier.doi10.1016/B978-0-08-097774-4.00339-9-
dc.identifier.scopuseid_2-s2.0-84902568580-
dc.identifier.hkuros220763en_US
dc.identifier.volume3en_US
dc.identifier.spage975en_US
dc.identifier.epage986en_US
dc.publisher.placeAmsterdam-

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