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Conference Paper: Preventing dental caries in Sjogren’s syndrome patients with fluoride varnish
Title | Preventing dental caries in Sjogren’s syndrome patients with fluoride varnish |
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Authors | |
Keywords | Caries Fluoride Sjögren's Syndrome |
Issue Date | 2012 |
Publisher | IADR |
Citation | The 2012 PER/IADR Congress, 12-15 September 2012. How to Cite? |
Abstract | OBJECTIVES: To evaluate the effectiveness of quarterly professionally applied fluoride varnish in preventing dental caries in Sjögren's Syndrome (SS) patients over 24 months. METHODS: At baseline, 85 SS patients (83 women and 2 men; 38 primary SS (pSS) and 47 secondary SS (sSS) cases , mean age = 50.5±9.8) participated in this study after obtaining informed consent and IRB approval. Status of the teeth was assessed by a single trained examiner in a clinical setting using CPI probes and mouth mirrors. After examination, subjects were randomly assigned to the test and placebo control groups. A 5% sodium fluoride varnish was applied to all tooth surfaces every three months by dentists not involved in the examination. Follow-up examinations by the same blinded examiner were performed every 6 months to record development of new caries. RESULTS: So far, 58 subjects (27 in test and 31 in control group) completed the study. Over the 2-year period, 7 (25.9 %) subjects of the test group and 14 (46.8%) subjects of the control group developed new caries (Chi-square test, p>0.05). The mean number of teeth with new carious cavities were 0.7 (s.d.=1.4) and 1.2 (s.d.=2.5) for the test and control groups, respectively (Mann-Whitney U test, p>0.05). The corresponding numbers for decayed tooth surfaces were 0.9 (s.d.=2.0) and 1.9 (s.d.=4.1) for the test and control groups, respectively (Mann-Whitney U test, p>0.05) . The prevented fraction was 52.6%. CONCLUSIONS: Based on the interim results of this on-going clinical trial, firm conclusion on the effectiveness on quarterly application of 5% sodium fluoride varnish in preventing dental caries in Sjögren's Syndrome patients cannot be drawn. |
Description | Poster Session 50. Behavioral, Epidemiologic and Health Services Research II: no. 357 |
Persistent Identifier | http://hdl.handle.net/10722/186552 |
DC Field | Value | Language |
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dc.contributor.author | Xin, W | en_US |
dc.contributor.author | Leung, KCM | en_US |
dc.contributor.author | Lo, ECM | en_US |
dc.date.accessioned | 2013-08-20T12:12:20Z | - |
dc.date.available | 2013-08-20T12:12:20Z | - |
dc.date.issued | 2012 | en_US |
dc.identifier.citation | The 2012 PER/IADR Congress, 12-15 September 2012. | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/186552 | - |
dc.description | Poster Session 50. Behavioral, Epidemiologic and Health Services Research II: no. 357 | - |
dc.description.abstract | OBJECTIVES: To evaluate the effectiveness of quarterly professionally applied fluoride varnish in preventing dental caries in Sjögren's Syndrome (SS) patients over 24 months. METHODS: At baseline, 85 SS patients (83 women and 2 men; 38 primary SS (pSS) and 47 secondary SS (sSS) cases , mean age = 50.5±9.8) participated in this study after obtaining informed consent and IRB approval. Status of the teeth was assessed by a single trained examiner in a clinical setting using CPI probes and mouth mirrors. After examination, subjects were randomly assigned to the test and placebo control groups. A 5% sodium fluoride varnish was applied to all tooth surfaces every three months by dentists not involved in the examination. Follow-up examinations by the same blinded examiner were performed every 6 months to record development of new caries. RESULTS: So far, 58 subjects (27 in test and 31 in control group) completed the study. Over the 2-year period, 7 (25.9 %) subjects of the test group and 14 (46.8%) subjects of the control group developed new caries (Chi-square test, p>0.05). The mean number of teeth with new carious cavities were 0.7 (s.d.=1.4) and 1.2 (s.d.=2.5) for the test and control groups, respectively (Mann-Whitney U test, p>0.05). The corresponding numbers for decayed tooth surfaces were 0.9 (s.d.=2.0) and 1.9 (s.d.=4.1) for the test and control groups, respectively (Mann-Whitney U test, p>0.05) . The prevented fraction was 52.6%. CONCLUSIONS: Based on the interim results of this on-going clinical trial, firm conclusion on the effectiveness on quarterly application of 5% sodium fluoride varnish in preventing dental caries in Sjögren's Syndrome patients cannot be drawn. | - |
dc.language | eng | en_US |
dc.publisher | IADR | - |
dc.relation.ispartof | PER/IADR Congress 2012 | en_US |
dc.subject | Caries | - |
dc.subject | Fluoride | - |
dc.subject | Sjögren's Syndrome | - |
dc.title | Preventing dental caries in Sjogren’s syndrome patients with fluoride varnish | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Leung, KCM: kcmleung@hkucc.hku.hk | en_US |
dc.identifier.email | Lo, ECM: hrdplcm@hkucc.hku.hk | en_US |
dc.identifier.authority | Leung, KCM=rp00032 | en_US |
dc.identifier.authority | Lo, ECM=rp00015 | en_US |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.hkuros | 220577 | en_US |
dc.publisher.place | United States | - |