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Article: Clomiphene citrate does not improve spermatozoal fertilizing capacity in idiopathic oligospermia

TitleClomiphene citrate does not improve spermatozoal fertilizing capacity in idiopathic oligospermia
Authors
Wang, CChan, SYWTang, LCHYeung, KK
Issue Date1985
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/fertnstert
Citation
Fertility And Sterility, 1985, v. 44 n. 1, p. 102-105 How to Cite?
AbstractClomiphene citrate (CC) was given to 24 men with idiopathic oligospermia at a daily dose of 25 mg (10 subjects) or 50 mg (14 subjects). Sperm concentration increased slightly after CC treatment in both groups. Sperm motility and morphology remained unchanged. Spermatozoal fertilizing capacity as assessed by the zona-free hamster ova penetration test showed no significant change throughout the treatment period. Two pregnancies occurred in the partners of the subjects treated with 50 mg CC/day, but none occurred in the other group. We conclude that oral administration of CC does not improve fertilizing capacity of sperm as measured by the zona-free hamster ova penetration test in idiopathic oligospermia.
Persistent Identifierhttp://hdl.handle.net/10722/184166
ISSN
0015-0282
2023 Impact Factor: 6.6
2023 SCImago Journal Rankings: 1.858
ISI Accession Number ID
WOS:A1985AMH8500018

 

DC FieldValueLanguage
dc.contributor.authorWang, Cen_US
dc.contributor.authorChan, SYWen_US
dc.contributor.authorTang, LCHen_US
dc.contributor.authorYeung, KKen_US
dc.date.accessioned2013-06-25T03:00:56Z-
dc.date.available2013-06-25T03:00:56Z-
dc.date.issued1985en_US
dc.identifier.citationFertility And Sterility, 1985, v. 44 n. 1, p. 102-105en_US
dc.identifier.issn0015-0282en_US
dc.identifier.urihttp://hdl.handle.net/10722/184166-
dc.description.abstractClomiphene citrate (CC) was given to 24 men with idiopathic oligospermia at a daily dose of 25 mg (10 subjects) or 50 mg (14 subjects). Sperm concentration increased slightly after CC treatment in both groups. Sperm motility and morphology remained unchanged. Spermatozoal fertilizing capacity as assessed by the zona-free hamster ova penetration test showed no significant change throughout the treatment period. Two pregnancies occurred in the partners of the subjects treated with 50 mg CC/day, but none occurred in the other group. We conclude that oral administration of CC does not improve fertilizing capacity of sperm as measured by the zona-free hamster ova penetration test in idiopathic oligospermia.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/fertnsterten_US
dc.relation.ispartofFertility and Sterilityen_US
dc.subject.meshAdulten_US
dc.subject.meshAnimalsen_US
dc.subject.meshClomiphene - Therapeutic Useen_US
dc.subject.meshCricetinaeen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshOligospermia - Drug Therapy - Physiopathologyen_US
dc.subject.meshSperm Counten_US
dc.subject.meshSperm Motility - Drug Effectsen_US
dc.subject.meshSperm-Ovum Interactions - Drug Effectsen_US
dc.subject.meshTime Factorsen_US
dc.titleClomiphene citrate does not improve spermatozoal fertilizing capacity in idiopathic oligospermiaen_US
dc.typeArticleen_US
dc.identifier.emailTang, LCH: lchtang@hku.hken_US
dc.identifier.authorityTang, LCH=rp01756en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid4007185-
dc.identifier.scopuseid_2-s2.0-0021818704en_US
dc.identifier.volume44en_US
dc.identifier.issue1en_US
dc.identifier.spage102en_US
dc.identifier.epage105en_US
dc.identifier.isiWOS:A1985AMH8500018-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridWang, C=7501631357en_US
dc.identifier.scopusauthoridChan, SYW=7404255960en_US
dc.identifier.scopusauthoridTang, LCH=7402081111en_US
dc.identifier.scopusauthoridYeung, KK=7202425010en_US
dc.identifier.issnl0015-0282-

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