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- Publisher Website: 10.1016/j.preteyeres.2007.12.001
- Scopus: eid_2-s2.0-40249097578
- PMID: 18249026
- WOS: WOS:000255104200002
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Article: Diabetic retinopathy and systemic vascular complications
Title | Diabetic retinopathy and systemic vascular complications |
---|---|
Authors | |
Keywords | Cardiovascular disease prediction Complications Coronary heart disease Heart failure Macrovascular disease Microvascular disease Mortality Nephropathy Retinopathy Stroke |
Issue Date | 2008 |
Publisher | Pergamon. The Journal's web site is located at http://www.elsevier.com/locate/preteyeres |
Citation | Progress In Retinal And Eye Research, 2008, v. 27 n. 2, p. 161-176 How to Cite? |
Abstract | Retinopathy is the most common complication of diabetes. The assessment of retinopathy signs presents clinicians a unique opportunity to directly visualize and assess the actual morphology of diabetic microvascular damage. Extensive studies have now shown that people with diabetic retinopathy have excess risks of systemic vascular complications, including subclinical and clinical stroke, coronary heart disease, heart failure, and nephropathy. There is also emerging evidence to suggest that diabetic retinopathy may share common genetic linkages with systemic vascular complications. The extant literature, therefore, supports the theory that diabetic retinopathy reflects widespread microcirculatory disease not only in the eye but also vital organs elsewhere in the body. Being a uniquely specific and non-invasively assessable measure of diabetic microvascular damage, retinopathy may also be envisioned as a novel biomarker of vascular disease risk in asymptomatic patients with diabetes. This review summarizes recent studies on the systemic associations of diabetic retinopathy, and discusses their pathophysiological significance and clinical implications. © 2007 Elsevier Ltd. All rights reserved. |
Persistent Identifier | http://hdl.handle.net/10722/183539 |
ISSN | 2023 Impact Factor: 18.6 2023 SCImago Journal Rankings: 5.923 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Cheung, N | en_US |
dc.contributor.author | Wong, TY | en_US |
dc.date.accessioned | 2013-05-28T06:14:32Z | - |
dc.date.available | 2013-05-28T06:14:32Z | - |
dc.date.issued | 2008 | en_US |
dc.identifier.citation | Progress In Retinal And Eye Research, 2008, v. 27 n. 2, p. 161-176 | en_US |
dc.identifier.issn | 1350-9462 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/183539 | - |
dc.description.abstract | Retinopathy is the most common complication of diabetes. The assessment of retinopathy signs presents clinicians a unique opportunity to directly visualize and assess the actual morphology of diabetic microvascular damage. Extensive studies have now shown that people with diabetic retinopathy have excess risks of systemic vascular complications, including subclinical and clinical stroke, coronary heart disease, heart failure, and nephropathy. There is also emerging evidence to suggest that diabetic retinopathy may share common genetic linkages with systemic vascular complications. The extant literature, therefore, supports the theory that diabetic retinopathy reflects widespread microcirculatory disease not only in the eye but also vital organs elsewhere in the body. Being a uniquely specific and non-invasively assessable measure of diabetic microvascular damage, retinopathy may also be envisioned as a novel biomarker of vascular disease risk in asymptomatic patients with diabetes. This review summarizes recent studies on the systemic associations of diabetic retinopathy, and discusses their pathophysiological significance and clinical implications. © 2007 Elsevier Ltd. All rights reserved. | en_US |
dc.language | eng | en_US |
dc.publisher | Pergamon. The Journal's web site is located at http://www.elsevier.com/locate/preteyeres | en_US |
dc.relation.ispartof | Progress in Retinal and Eye Research | en_US |
dc.subject | Cardiovascular disease prediction | - |
dc.subject | Complications | - |
dc.subject | Coronary heart disease | - |
dc.subject | Heart failure | - |
dc.subject | Macrovascular disease | - |
dc.subject | Microvascular disease | - |
dc.subject | Mortality | - |
dc.subject | Nephropathy | - |
dc.subject | Retinopathy | - |
dc.subject | Stroke | - |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Diabetic Retinopathy - Complications - Genetics - Physiopathology | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Vascular Diseases - Complications - Genetics - Physiopathology | en_US |
dc.title | Diabetic retinopathy and systemic vascular complications | en_US |
dc.type | Article | en_US |
dc.identifier.email | Cheung, N: dannycheung@hotmail.com | en_US |
dc.identifier.authority | Cheung, N=rp01752 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/j.preteyeres.2007.12.001 | en_US |
dc.identifier.pmid | 18249026 | - |
dc.identifier.scopus | eid_2-s2.0-40249097578 | en_US |
dc.identifier.volume | 27 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.spage | 161 | en_US |
dc.identifier.epage | 176 | en_US |
dc.identifier.isi | WOS:000255104200002 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Cheung, N=8054683900 | en_US |
dc.identifier.scopusauthorid | Wong, TY=7403531208 | en_US |
dc.identifier.issnl | 1350-9462 | - |