File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Conference Paper: Brain response in the processing of Chinese characters: An event-related fMRI study

TitleBrain response in the processing of Chinese characters: An event-related fMRI study
Authors
KeywordsChinese
Event-Related
Fmri
Language
Mri
Issue Date2000
Citation
Annual International Conference Of The Ieee Engineering In Medicine And Biology - Proceedings, 2000, v. 3, p. 2020-2024 How to Cite?
AbstractDue to the entirely different surface form of the writing system and the large population of native speakers, Chinese (Mandarin) processing has evoked broad interests in the field of language study. Recently, fMRI with blocked design has been used in the mapping of Chinese language processing. Comparing to blocked task design, event-related task design takes the advantages of the high temporal resolution of fMRI and provides greater experimental flexibility in task design. In this study, we examine event-related fMRI (ER-fMRI) response in the process of Chinese characters. Experiments were performed on a 1.9 T GE/Elscint Prestige MRI scanner, with six subjects. A gradient-echo EPI sequence was used. Ten axial slices were acquired. A single Chinese character was used for each stimulus. The subjects were asked to perform a word generation task. In all the subjects, strong activation was detected in left middle to inferior prefrontal gyri. Highly left hemisphere dominance of the activation in prefrontal cortex was observed in all the subjects, with the locations in well agreement with the previous studies using blocked design. Percent maximum BOLD signal change was 1.45 ± 0.14%, averaged across the six subjects. Time-to-peak was 7.72 ± 0.31 sec, and FWHM was 5.99 ± 0.43 sec. In this study, we demonstrated that ER-fMRI signal change can be reliably detected in single subject, with response to repeated single trials of Chinese character processing. Based on this result, more sophisticated paradigm design can be utilized in the future study of Chinese language.
Persistent Identifierhttp://hdl.handle.net/10722/179869
ISSN
2023 SCImago Journal Rankings: 0.340

 

DC FieldValueLanguage
dc.contributor.authorLiu, HLen_US
dc.contributor.authorPu, Yen_US
dc.contributor.authorFeng, CMen_US
dc.contributor.authorTan, LHen_US
dc.contributor.authorSpinks, JAen_US
dc.contributor.authorPerfetti, CAen_US
dc.contributor.authorXiong, Jen_US
dc.contributor.authorFox, PTen_US
dc.contributor.authorGao, JHen_US
dc.date.accessioned2012-12-19T10:07:12Z-
dc.date.available2012-12-19T10:07:12Z-
dc.date.issued2000en_US
dc.identifier.citationAnnual International Conference Of The Ieee Engineering In Medicine And Biology - Proceedings, 2000, v. 3, p. 2020-2024en_US
dc.identifier.issn0589-1019en_US
dc.identifier.urihttp://hdl.handle.net/10722/179869-
dc.description.abstractDue to the entirely different surface form of the writing system and the large population of native speakers, Chinese (Mandarin) processing has evoked broad interests in the field of language study. Recently, fMRI with blocked design has been used in the mapping of Chinese language processing. Comparing to blocked task design, event-related task design takes the advantages of the high temporal resolution of fMRI and provides greater experimental flexibility in task design. In this study, we examine event-related fMRI (ER-fMRI) response in the process of Chinese characters. Experiments were performed on a 1.9 T GE/Elscint Prestige MRI scanner, with six subjects. A gradient-echo EPI sequence was used. Ten axial slices were acquired. A single Chinese character was used for each stimulus. The subjects were asked to perform a word generation task. In all the subjects, strong activation was detected in left middle to inferior prefrontal gyri. Highly left hemisphere dominance of the activation in prefrontal cortex was observed in all the subjects, with the locations in well agreement with the previous studies using blocked design. Percent maximum BOLD signal change was 1.45 ± 0.14%, averaged across the six subjects. Time-to-peak was 7.72 ± 0.31 sec, and FWHM was 5.99 ± 0.43 sec. In this study, we demonstrated that ER-fMRI signal change can be reliably detected in single subject, with response to repeated single trials of Chinese character processing. Based on this result, more sophisticated paradigm design can be utilized in the future study of Chinese language.en_US
dc.languageengen_US
dc.relation.ispartofAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedingsen_US
dc.subjectChineseen_US
dc.subjectEvent-Relateden_US
dc.subjectFmrien_US
dc.subjectLanguageen_US
dc.subjectMrien_US
dc.titleBrain response in the processing of Chinese characters: An event-related fMRI studyen_US
dc.typeConference_Paperen_US
dc.identifier.emailTan, LH: tanlh@hku.hken_US
dc.identifier.emailSpinks, JA: spinks@hku.hken_US
dc.identifier.authorityTan, LH=rp01202en_US
dc.identifier.authoritySpinks, JA=rp00063en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-0034442650en_US
dc.identifier.volume3en_US
dc.identifier.spage2020en_US
dc.identifier.epage2024en_US
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLiu, HL=7409756284en_US
dc.identifier.scopusauthoridPu, Y=7103191393en_US
dc.identifier.scopusauthoridFeng, CM=7402911502en_US
dc.identifier.scopusauthoridTan, LH=7402233462en_US
dc.identifier.scopusauthoridSpinks, JA=6701628658en_US
dc.identifier.scopusauthoridPerfetti, CA=7005318729en_US
dc.identifier.scopusauthoridXiong, J=7202010007en_US
dc.identifier.scopusauthoridFox, PT=7402680249en_US
dc.identifier.scopusauthoridGao, JH=7404475674en_US
dc.identifier.issnl0589-1019-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats