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Article: Acetophenone glycosides from thyme (Thymus vulgaris L.)

TitleAcetophenone glycosides from thyme (Thymus vulgaris L.)
Authors
Wang, MKikuzaki, HLin, CCKahyaoglu, AHuang, MTNakatani, NHo, CT
KeywordsAcetophenone glycoside
Thyme
Thymus vulgaris L.
Issue Date1999
PublisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journal/jafcau
Citation
Journal Of Agricultural And Food Chemistry, 1999, v. 47 n. 5, p. 1911-1914 How to Cite?
DOI: http://dx.doi.org/10.1021/jf981282d
AbstractFour acetophenone glycosides were isolated from the butanol-soluble fraction of thyme extracts. Their structures were determined by spectral methods (MS, NMR, and 2D-NMR). Among them, two new compounds, 4- hydroxyacetophenone 4-O-[5-O-(3,5-dimethoxy-4-hydroxybenzoyl)-β-D- apiofuranosyl]-(1-2)-β-D-glucopyranoside (1) and 4-hydroxyacetophenone 4-O- [5-O-(4-hydroxybenzoyl)β-D-apiofuranosyl]-(1-2)-β-D-glucopyranoside (2), were determined. Compound 1 showed weak cytotoxicity, inhibiting DNA synthesis of human leukemia cells.
Persistent Identifierhttp://hdl.handle.net/10722/178652
ISSN
0021-8561
2021 Impact Factor: 5.895
2020 SCImago Journal Rankings: 1.203
ISI Accession Number ID
WOS:000080427200019
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorWang, Men_US
dc.contributor.authorKikuzaki, Hen_US
dc.contributor.authorLin, CCen_US
dc.contributor.authorKahyaoglu, Aen_US
dc.contributor.authorHuang, MTen_US
dc.contributor.authorNakatani, Nen_US
dc.contributor.authorHo, CTen_US
dc.date.accessioned2012-12-19T09:48:57Z-
dc.date.available2012-12-19T09:48:57Z-
dc.date.issued1999en_US
dc.identifier.citationJournal Of Agricultural And Food Chemistry, 1999, v. 47 n. 5, p. 1911-1914en_US
dc.identifier.issn0021-8561en_US
dc.identifier.urihttp://hdl.handle.net/10722/178652-
dc.description.abstractFour acetophenone glycosides were isolated from the butanol-soluble fraction of thyme extracts. Their structures were determined by spectral methods (MS, NMR, and 2D-NMR). Among them, two new compounds, 4- hydroxyacetophenone 4-O-[5-O-(3,5-dimethoxy-4-hydroxybenzoyl)-β-D- apiofuranosyl]-(1-2)-β-D-glucopyranoside (1) and 4-hydroxyacetophenone 4-O- [5-O-(4-hydroxybenzoyl)β-D-apiofuranosyl]-(1-2)-β-D-glucopyranoside (2), were determined. Compound 1 showed weak cytotoxicity, inhibiting DNA synthesis of human leukemia cells.en_US
dc.languageengen_US
dc.publisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journal/jafcauen_US
dc.relation.ispartofJournal of Agricultural and Food Chemistryen_US
dc.subjectAcetophenone glycoside-
dc.subjectThyme-
dc.subjectThymus vulgaris L.-
dc.subject.meshAcetophenones - Chemistry - Isolation & Purificationen_US
dc.subject.meshAngiosperms - Chemistryen_US
dc.subject.meshAntineoplastic Agents, Phytogenic - Chemistry - Isolation & Purification - Toxicityen_US
dc.subject.meshCell Division - Drug Effectsen_US
dc.subject.meshCell Survival - Drug Effectsen_US
dc.subject.meshDna, Neoplasm - Biosynthesis - Drug Effectsen_US
dc.subject.meshGlycosides - Chemistry - Isolation & Purificationen_US
dc.subject.meshHl-60 Cellsen_US
dc.subject.meshHumansen_US
dc.subject.meshLamiaceae - Chemistryen_US
dc.subject.meshMolecular Structureen_US
dc.titleAcetophenone glycosides from thyme (Thymus vulgaris L.)en_US
dc.typeArticleen_US
dc.identifier.emailWang, M: mfwang@hku.hken_US
dc.identifier.authorityWang, M=rp00800en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1021/jf981282den_US
dc.identifier.pmid10552470-
dc.identifier.scopuseid_2-s2.0-0032821909en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032821909&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume47en_US
dc.identifier.issue5en_US
dc.identifier.spage1911en_US
dc.identifier.epage1914en_US
dc.identifier.isiWOS:000080427200019-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridWang, M=7406691844en_US
dc.identifier.scopusauthoridKikuzaki, H=7003452974en_US
dc.identifier.scopusauthoridLin, CC=9432378600en_US
dc.identifier.scopusauthoridKahyaoglu, A=6506584601en_US
dc.identifier.scopusauthoridHuang, MT=7404259758en_US
dc.identifier.scopusauthoridNakatani, N=7102434865en_US
dc.identifier.scopusauthoridHo, CT=7404652573en_US
dc.identifier.issnl0021-8561-

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