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- Publisher Website: 10.1210/endo-118-5-1961
- Scopus: eid_2-s2.0-0022647670
- PMID: 3084211
- WOS: WOS:A1986C003400032
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Article: Purified chicken growth hormone (GH) and a human pancreatic GH-releasing hormone increase body weight gain in chickens
Title | Purified chicken growth hormone (GH) and a human pancreatic GH-releasing hormone increase body weight gain in chickens |
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Authors | |
Issue Date | 1986 |
Publisher | The Endocrine Society. The Journal's web site is located at http://endo.endojournals.org |
Citation | Endocrinology, 1986, v. 118 n. 5, p. 1961-1965 How to Cite? |
Abstract | Purified chicken GH (cGH) and a synthetic human GH-releasing hormone (hpGRF) were tested for the ability to improve growth performance in chickens. Purified cGH was given to 4-week-old cockerels at 5, 10, and 50 μg/day for 14 days via daily iv injection. Body weights of chickens receiving 5 and 10 μg/day cGH were significantly increased at 6 days by 13.5% and 11.2%, respectively, relative to control values. At 14 days, body weights averaged 8.1% and 7.7% greater than controls, but these values were not statistically significant. There was a slight stimulation of body weight gain in chickens receiving 50 μg/day cGH. In general, cGH produces a transient stimulation of body weight gain in chickens. hpGRF was also given to 4-week-old cockerels for 14 days via daily iv injection at 0.1, 1.0, and 10.0 μg/day. hpGRF at 0.1 μg/bird daily increased body weight on day 14 (9.1% over the control value). The stimulating effects of hpGRF on body weight are also transient. The effects of cGH on serum somatomedin-C (SM-C) were examined. Serum SM-C concentrations were significantly elevated 24 and 36 h after injection of cGH. In conclusion, purified cGH and hpGRF appear to have some growth-promoting activity. The stimulatory effect of hpGRF on weight gain may be mediated via GH, and the stimulatory effect on cGH could be mediated through SM-C. |
Persistent Identifier | http://hdl.handle.net/10722/178448 |
ISSN | 2023 Impact Factor: 3.8 2023 SCImago Journal Rankings: 1.285 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Leung, FC | en_US |
dc.contributor.author | Taylor, JE | en_US |
dc.contributor.author | Wien, S | en_US |
dc.contributor.author | Van Iderstine, A | en_US |
dc.date.accessioned | 2012-12-19T09:47:45Z | - |
dc.date.available | 2012-12-19T09:47:45Z | - |
dc.date.issued | 1986 | en_US |
dc.identifier.citation | Endocrinology, 1986, v. 118 n. 5, p. 1961-1965 | en_US |
dc.identifier.issn | 0013-7227 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/178448 | - |
dc.description.abstract | Purified chicken GH (cGH) and a synthetic human GH-releasing hormone (hpGRF) were tested for the ability to improve growth performance in chickens. Purified cGH was given to 4-week-old cockerels at 5, 10, and 50 μg/day for 14 days via daily iv injection. Body weights of chickens receiving 5 and 10 μg/day cGH were significantly increased at 6 days by 13.5% and 11.2%, respectively, relative to control values. At 14 days, body weights averaged 8.1% and 7.7% greater than controls, but these values were not statistically significant. There was a slight stimulation of body weight gain in chickens receiving 50 μg/day cGH. In general, cGH produces a transient stimulation of body weight gain in chickens. hpGRF was also given to 4-week-old cockerels for 14 days via daily iv injection at 0.1, 1.0, and 10.0 μg/day. hpGRF at 0.1 μg/bird daily increased body weight on day 14 (9.1% over the control value). The stimulating effects of hpGRF on body weight are also transient. The effects of cGH on serum somatomedin-C (SM-C) were examined. Serum SM-C concentrations were significantly elevated 24 and 36 h after injection of cGH. In conclusion, purified cGH and hpGRF appear to have some growth-promoting activity. The stimulatory effect of hpGRF on weight gain may be mediated via GH, and the stimulatory effect on cGH could be mediated through SM-C. | en_US |
dc.language | eng | en_US |
dc.publisher | The Endocrine Society. The Journal's web site is located at http://endo.endojournals.org | en_US |
dc.relation.ispartof | Endocrinology | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Body Weight - Drug Effects | en_US |
dc.subject.mesh | Chickens - Growth & Development | en_US |
dc.subject.mesh | Growth Hormone - Metabolism - Pharmacology | en_US |
dc.subject.mesh | Growth Hormone-Releasing Hormone - Pharmacology | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Insulin-Like Growth Factor I - Blood | en_US |
dc.subject.mesh | Liver - Drug Effects - Metabolism | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Pancreas - Analysis | en_US |
dc.title | Purified chicken growth hormone (GH) and a human pancreatic GH-releasing hormone increase body weight gain in chickens | en_US |
dc.type | Article | en_US |
dc.identifier.email | Leung, FC: fcleung@hkucc.hku.hk | en_US |
dc.identifier.authority | Leung, FC=rp00731 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1210/endo-118-5-1961 | - |
dc.identifier.pmid | 3084211 | - |
dc.identifier.scopus | eid_2-s2.0-0022647670 | en_US |
dc.identifier.volume | 118 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.spage | 1961 | en_US |
dc.identifier.epage | 1965 | en_US |
dc.identifier.isi | WOS:A1986C003400032 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Leung, FC=7103078633 | en_US |
dc.identifier.scopusauthorid | Taylor, JE=7405405625 | en_US |
dc.identifier.scopusauthorid | Wien, S=55317365000 | en_US |
dc.identifier.scopusauthorid | Van Iderstine, A=6602377005 | en_US |
dc.identifier.issnl | 0013-7227 | - |