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Article: Generic number systems and haplotype analysis

TitleGeneric number systems and haplotype analysis
Authors
KeywordsEM algorithm
Gene-counting
Mixed-radix number
Number theory
Radix sort
Issue Date2003
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/cmpb
Citation
Computer Methods And Programs In Biomedicine, 2003, v. 70 n. 1, p. 1-9 How to Cite?
AbstractThree simple and elegant algorithms involving binary and mixed-radix numbers are presented as C subroutines and applied to gene-counting procedure. The first, a multikey radix-sorting subroutine, is used to tally individuals with similar genetic marker information. The second, a subroutine for N-ary number addition, is used to enumerate all possible phases of a heterozygote. The third, a mixed-radix number subroutine, is used to generate all haplotypes and indexing single array of haplotype frequencies. Examples exposing these algorithms are also given. The sorting algorithm entails broad application while the N-ary and mixed-radix number algorithms are very efficient for generic looping. Implementation of gene-counting using these algorithms avoids use of multilocus genotype identifier and improves its portability to other analysis. © 2002 Elsevier Science Ireland Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/175882
ISSN
2023 Impact Factor: 4.9
2023 SCImago Journal Rankings: 1.189
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZhao, JHen_US
dc.contributor.authorSham, PCen_US
dc.date.accessioned2012-11-26T09:02:08Z-
dc.date.available2012-11-26T09:02:08Z-
dc.date.issued2003en_US
dc.identifier.citationComputer Methods And Programs In Biomedicine, 2003, v. 70 n. 1, p. 1-9en_US
dc.identifier.issn0169-2607en_US
dc.identifier.urihttp://hdl.handle.net/10722/175882-
dc.description.abstractThree simple and elegant algorithms involving binary and mixed-radix numbers are presented as C subroutines and applied to gene-counting procedure. The first, a multikey radix-sorting subroutine, is used to tally individuals with similar genetic marker information. The second, a subroutine for N-ary number addition, is used to enumerate all possible phases of a heterozygote. The third, a mixed-radix number subroutine, is used to generate all haplotypes and indexing single array of haplotype frequencies. Examples exposing these algorithms are also given. The sorting algorithm entails broad application while the N-ary and mixed-radix number algorithms are very efficient for generic looping. Implementation of gene-counting using these algorithms avoids use of multilocus genotype identifier and improves its portability to other analysis. © 2002 Elsevier Science Ireland Ltd. All rights reserved.en_US
dc.languageengen_US
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/cmpben_US
dc.relation.ispartofComputer Methods and Programs in Biomedicineen_US
dc.subjectEM algorithm-
dc.subjectGene-counting-
dc.subjectMixed-radix number-
dc.subjectNumber theory-
dc.subjectRadix sort-
dc.subject.meshAlgorithmsen_US
dc.subject.meshAllelesen_US
dc.subject.meshGenetic Markersen_US
dc.subject.meshHaplotypesen_US
dc.titleGeneric number systems and haplotype analysisen_US
dc.typeArticleen_US
dc.identifier.emailSham, PC: pcsham@hku.hken_US
dc.identifier.authoritySham, PC=rp00459en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0169-2607(01)00193-6en_US
dc.identifier.pmid12468122-
dc.identifier.scopuseid_2-s2.0-0037211967en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0037211967&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume70en_US
dc.identifier.issue1en_US
dc.identifier.spage1en_US
dc.identifier.epage9en_US
dc.identifier.isiWOS:000180499300001-
dc.publisher.placeIrelanden_US
dc.identifier.scopusauthoridZhao, JH=7410311266en_US
dc.identifier.scopusauthoridSham, PC=34573429300en_US
dc.identifier.issnl0169-2607-

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