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Article: Model-free analysis and permutation tests for allelic associations

TitleModel-free analysis and permutation tests for allelic associations
Authors
Zhao, JHCurtis, DSham, PC
KeywordsAllelic association
Case-control design
Haplotype analysis
Model-free association analysis
Permutation test
Issue Date2000
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/HHE
Citation
Human Heredity, 2000, v. 50 n. 2, p. 133-139 How to Cite?
DOI: http://dx.doi.org/10.1159/000022901
AbstractIn this short report, we address some practical problems in performing likelihood-based allelic association analysis of case-control data. Model-free statistics are proposed and their properties assessed by simulation, and procedures based on permutation tests are described for marker-marker as well as marker-disease associations. A memory-efficient algorithm is developed which enables several highly polymorphic markers to be analysed.
Persistent Identifierhttp://hdl.handle.net/10722/175821
ISSN
0001-5652
2021 Impact Factor: 1.455
2020 SCImago Journal Rankings: 0.423
ISI Accession Number ID
WOS:000084056600006
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorZhao, JHen_US
dc.contributor.authorCurtis, Den_US
dc.contributor.authorSham, PCen_US
dc.date.accessioned2012-11-26T09:01:34Z-
dc.date.available2012-11-26T09:01:34Z-
dc.date.issued2000en_US
dc.identifier.citationHuman Heredity, 2000, v. 50 n. 2, p. 133-139en_US
dc.identifier.issn0001-5652en_US
dc.identifier.urihttp://hdl.handle.net/10722/175821-
dc.description.abstractIn this short report, we address some practical problems in performing likelihood-based allelic association analysis of case-control data. Model-free statistics are proposed and their properties assessed by simulation, and procedures based on permutation tests are described for marker-marker as well as marker-disease associations. A memory-efficient algorithm is developed which enables several highly polymorphic markers to be analysed.en_US
dc.languageengen_US
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/HHEen_US
dc.relation.ispartofHuman Heredityen_US
dc.subjectAllelic association-
dc.subjectCase-control design-
dc.subjectHaplotype analysis-
dc.subjectModel-free association analysis-
dc.subjectPermutation test-
dc.subject.meshAlgorithmsen_US
dc.subject.meshAllelesen_US
dc.subject.meshGenotypeen_US
dc.subject.meshHaplotypesen_US
dc.subject.meshModels, Geneticen_US
dc.subject.meshSoftwareen_US
dc.titleModel-free analysis and permutation tests for allelic associationsen_US
dc.typeArticleen_US
dc.identifier.emailSham, PC: pcsham@hku.hken_US
dc.identifier.authoritySham, PC=rp00459en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1159/000022901-
dc.identifier.pmid10799972-
dc.identifier.scopuseid_2-s2.0-0033990339en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0033990339&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume50en_US
dc.identifier.issue2en_US
dc.identifier.spage133en_US
dc.identifier.epage139en_US
dc.identifier.isiWOS:000084056600006-
dc.publisher.placeSwitzerlanden_US
dc.identifier.scopusauthoridZhao, JH=7410311266en_US
dc.identifier.scopusauthoridCurtis, D=14633020700en_US
dc.identifier.scopusauthoridSham, PC=34573429300en_US
dc.identifier.issnl0001-5652-

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