File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Scopus: eid_2-s2.0-0027176866
- PMID: 8317403
- WOS: WOS:A1993LL28600011
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Frequent occurrence of new hepatobiliary abnormalities after bone marrow transplantation: Results of a prospective study using scintigraphy and sonography
Title | Frequent occurrence of new hepatobiliary abnormalities after bone marrow transplantation: Results of a prospective study using scintigraphy and sonography |
---|---|
Authors | |
Issue Date | 1993 |
Publisher | Nature Publishing Group. The Journal's web site is located at http://www.nature.com/ajg/index.html |
Citation | American Journal Of Gastroenterology, 1993, v. 88 n. 7, p. 1044-1049 How to Cite? |
Abstract | With hepatobiliary scintigraphy and sonography, we prospectively studied the occurrence of new hepatobiliary abnormalities in 18 patients before, and from 1 to 103 days after, bone marrow transplantation (BMT). Prior to BMT, all patients had normal hepatic uptake and visualization of the gallbladder by 60 min on scintigraphy, and no sludge, stones, or other abnormalities on sonography. After BMT, 16 patients (89%) developed new scintigraphic and/or sonographic hepatobiliary abnormalities. Fifteen patients had impaired liver uptake of mebrofenin, while 11 developed gallbladder sludge and/or stones, and 10 had gallbladder nonvisualization at 60 min. Nevertheless, no patient developed clinical or laboratory evidence of acute cholecystitis. New hepatobiliary abnormalities are more common during the first months post-BMT than clinically suspected, probably reflecting the combined effects of hepatotoxic chemoradiation therapy, graft-versus-host disease, and prolonged administration of parenteral alimentation. Evidence of acute cholecystitis is generally not found. |
Persistent Identifier | http://hdl.handle.net/10722/175681 |
ISSN | 2023 Impact Factor: 8.0 2023 SCImago Journal Rankings: 2.391 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jacobson, AF | en_US |
dc.contributor.author | Teefey, SA | en_US |
dc.contributor.author | Lee, SP | en_US |
dc.contributor.author | Hollister, MS | en_US |
dc.contributor.author | Higano, CA | en_US |
dc.contributor.author | Bianco, JA | en_US |
dc.date.accessioned | 2012-11-26T09:00:28Z | - |
dc.date.available | 2012-11-26T09:00:28Z | - |
dc.date.issued | 1993 | en_US |
dc.identifier.citation | American Journal Of Gastroenterology, 1993, v. 88 n. 7, p. 1044-1049 | en_US |
dc.identifier.issn | 0002-9270 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/175681 | - |
dc.description.abstract | With hepatobiliary scintigraphy and sonography, we prospectively studied the occurrence of new hepatobiliary abnormalities in 18 patients before, and from 1 to 103 days after, bone marrow transplantation (BMT). Prior to BMT, all patients had normal hepatic uptake and visualization of the gallbladder by 60 min on scintigraphy, and no sludge, stones, or other abnormalities on sonography. After BMT, 16 patients (89%) developed new scintigraphic and/or sonographic hepatobiliary abnormalities. Fifteen patients had impaired liver uptake of mebrofenin, while 11 developed gallbladder sludge and/or stones, and 10 had gallbladder nonvisualization at 60 min. Nevertheless, no patient developed clinical or laboratory evidence of acute cholecystitis. New hepatobiliary abnormalities are more common during the first months post-BMT than clinically suspected, probably reflecting the combined effects of hepatotoxic chemoradiation therapy, graft-versus-host disease, and prolonged administration of parenteral alimentation. Evidence of acute cholecystitis is generally not found. | en_US |
dc.language | eng | en_US |
dc.publisher | Nature Publishing Group. The Journal's web site is located at http://www.nature.com/ajg/index.html | en_US |
dc.relation.ispartof | American Journal of Gastroenterology | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Bone Marrow Transplantation - Adverse Effects | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Gallbladder - Radionuclide Imaging - Ultrasonography | en_US |
dc.subject.mesh | Gallbladder Diseases - Etiology - Radionuclide Imaging - Ultrasonography | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Liver - Radionuclide Imaging - Ultrasonography | en_US |
dc.subject.mesh | Liver Diseases - Etiology - Radionuclide Imaging - Ultrasonography | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Prospective Studies | en_US |
dc.title | Frequent occurrence of new hepatobiliary abnormalities after bone marrow transplantation: Results of a prospective study using scintigraphy and sonography | en_US |
dc.type | Article | en_US |
dc.identifier.email | Lee, SP: sumlee@hku.hk | en_US |
dc.identifier.authority | Lee, SP=rp01351 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.pmid | 8317403 | - |
dc.identifier.scopus | eid_2-s2.0-0027176866 | en_US |
dc.identifier.volume | 88 | en_US |
dc.identifier.issue | 7 | en_US |
dc.identifier.spage | 1044 | en_US |
dc.identifier.epage | 1049 | en_US |
dc.identifier.isi | WOS:A1993LL28600011 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Jacobson, AF=7403204421 | en_US |
dc.identifier.scopusauthorid | Teefey, SA=7003608392 | en_US |
dc.identifier.scopusauthorid | Lee, SP=7601417497 | en_US |
dc.identifier.scopusauthorid | Hollister, MS=6602982159 | en_US |
dc.identifier.scopusauthorid | Higano, CA=7004197065 | en_US |
dc.identifier.scopusauthorid | Bianco, JA=35397676700 | en_US |
dc.identifier.issnl | 0002-9270 | - |