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Conference Paper: Arterial wall: A new pharmacological and therapeutic target | LA PAROI ARTERIELLE: UNE NOUVELLE CIBLE PHARMACOLOGIQUE ET THERAPEUTIQUE?
Title | Arterial wall: A new pharmacological and therapeutic target | LA PAROI ARTERIELLE: UNE NOUVELLE CIBLE PHARMACOLOGIQUE ET THERAPEUTIQUE? |
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Authors | |
Keywords | Angiotensin Ii Receptor Antagonists Arterial Remodelling Atherosclerosis Endothelin Receptor Antagonists Endothelium Nitrates No Donors Potassium Channel Activators Proteoglycans |
Issue Date | 1995 |
Publisher | Adis International Ltd. The Journal's web site is located at http://www.pharmacol-fr.org/therapie/ |
Citation | Therapie, 1995, v. 50 n. 4, p. 387-398 How to Cite? |
Abstract | In recent years, endothelial dysfunction and arterial remodelling in various cardiovascular diseases have emerged as two key concepts, with numerous interrelationships. Both endothelial dysfunction and arterial remodelling occur in various pathologies including heart failure, atherosclerosis, restenosis after angioplasty, and pulmonary hypertension, and have modified the therapeutic approach by offering new pharmacological targets: specific receptors not only at the site of the vascular smooth muscle cells but also on the endothelial cells, growth factors that stimulate proliferation of smooth muscle, and receptors and enzymes of the extracellular matrix. Among the various substances under research, the present review will discuss angiotensin II receptor antagonists, endothelin receptor antagonists, nitrates-NO donors, potassium channel activators, and substances interfering with proteoglycans and other components of the extracellular matrix. |
Persistent Identifier | http://hdl.handle.net/10722/173526 |
ISSN | 2023 Impact Factor: 2.2 2023 SCImago Journal Rankings: 0.456 |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Laurent, S | en_US |
dc.contributor.author | Vanhoutte, P | en_US |
dc.contributor.author | Cavero, I | en_US |
dc.contributor.author | Chabrier, PE | en_US |
dc.contributor.author | Dupuis, B | en_US |
dc.contributor.author | Elghozi, JL | en_US |
dc.contributor.author | Hamon, G | en_US |
dc.contributor.author | Janiak, P | en_US |
dc.contributor.author | Juillet, Y | en_US |
dc.contributor.author | Kher, A | en_US |
dc.contributor.author | Koen, R | en_US |
dc.contributor.author | Madonna, O | en_US |
dc.contributor.author | Maffrand, JP | en_US |
dc.contributor.author | Pruneau, D | en_US |
dc.contributor.author | Thuillez, C | en_US |
dc.contributor.author | Mourad, JJ | en_US |
dc.date.accessioned | 2012-10-30T06:32:31Z | - |
dc.date.available | 2012-10-30T06:32:31Z | - |
dc.date.issued | 1995 | en_US |
dc.identifier.citation | Therapie, 1995, v. 50 n. 4, p. 387-398 | en_US |
dc.identifier.issn | 0040-5957 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/173526 | - |
dc.description.abstract | In recent years, endothelial dysfunction and arterial remodelling in various cardiovascular diseases have emerged as two key concepts, with numerous interrelationships. Both endothelial dysfunction and arterial remodelling occur in various pathologies including heart failure, atherosclerosis, restenosis after angioplasty, and pulmonary hypertension, and have modified the therapeutic approach by offering new pharmacological targets: specific receptors not only at the site of the vascular smooth muscle cells but also on the endothelial cells, growth factors that stimulate proliferation of smooth muscle, and receptors and enzymes of the extracellular matrix. Among the various substances under research, the present review will discuss angiotensin II receptor antagonists, endothelin receptor antagonists, nitrates-NO donors, potassium channel activators, and substances interfering with proteoglycans and other components of the extracellular matrix. | en_US |
dc.language | eng | en_US |
dc.publisher | Adis International Ltd. The Journal's web site is located at http://www.pharmacol-fr.org/therapie/ | en_US |
dc.relation.ispartof | Therapie | en_US |
dc.subject | Angiotensin Ii Receptor Antagonists | en_US |
dc.subject | Arterial Remodelling | en_US |
dc.subject | Atherosclerosis | en_US |
dc.subject | Endothelin Receptor Antagonists | en_US |
dc.subject | Endothelium | en_US |
dc.subject | Nitrates | en_US |
dc.subject | No Donors | en_US |
dc.subject | Potassium Channel Activators | en_US |
dc.subject | Proteoglycans | en_US |
dc.title | Arterial wall: A new pharmacological and therapeutic target | LA PAROI ARTERIELLE: UNE NOUVELLE CIBLE PHARMACOLOGIQUE ET THERAPEUTIQUE? | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Vanhoutte, P:vanhoutt@hku.hk | en_US |
dc.identifier.authority | Vanhoutte, P=rp00238 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.scopus | eid_2-s2.0-0029084494 | en_US |
dc.identifier.volume | 50 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.spage | 387 | en_US |
dc.identifier.epage | 398 | en_US |
dc.publisher.place | New Zealand | en_US |
dc.identifier.scopusauthorid | Laurent, S=7102779577 | en_US |
dc.identifier.scopusauthorid | Vanhoutte, P=7202304247 | en_US |
dc.identifier.scopusauthorid | Cavero, I=7006668310 | en_US |
dc.identifier.scopusauthorid | Chabrier, PE=7005988764 | en_US |
dc.identifier.scopusauthorid | Dupuis, B=7005189900 | en_US |
dc.identifier.scopusauthorid | Elghozi, JL=7006937210 | en_US |
dc.identifier.scopusauthorid | Hamon, G=7003320119 | en_US |
dc.identifier.scopusauthorid | Janiak, P=6603686655 | en_US |
dc.identifier.scopusauthorid | Juillet, Y=7005174082 | en_US |
dc.identifier.scopusauthorid | Kher, A=36917111000 | en_US |
dc.identifier.scopusauthorid | Koen, R=6603112958 | en_US |
dc.identifier.scopusauthorid | Madonna, O=6602744871 | en_US |
dc.identifier.scopusauthorid | Maffrand, JP=7005521190 | en_US |
dc.identifier.scopusauthorid | Pruneau, D=7005510301 | en_US |
dc.identifier.scopusauthorid | Thuillez, C=7005267110 | en_US |
dc.identifier.scopusauthorid | Mourad, JJ=7006408071 | en_US |
dc.identifier.issnl | 0040-5957 | - |