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- Scopus: eid_2-s2.0-59649104695
- PMID: 19038075
- WOS: WOS:000443030400008
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Article: Hemoglobin köln and pregnancy.
Title | Hemoglobin köln and pregnancy. |
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Authors | |
Keywords | Hemoglobin Köln Hemoglobinopathy Low oxygen saturation Pregnancy Pulse oximetry Thrombocytopenia Unstable hemoglobin |
Issue Date | 2008 |
Publisher | Canadian Medical Association. The Journal's web site is located at http://sogc.medical.org/JOGC/index_e.shtml |
Citation | Journal Of Obstetrics And Gynaecology Canada : Jogc = Journal D'obstétrique Et Gynécologie Du Canada : Jogc, 2008, v. 30 n. 10, p. 907-909 How to Cite? |
Abstract | BACKGROUND: Patients with hemoglobin Köln usually present with a mild hemolytic anemia characterized by reticulocytosis, splenomegaly, and elevated circulating bilirubin and lactate dehydrogenase levels. There have been no previous reports of whether these characteristics change during pregnancy and whether pregnancy provides any specific concerns for patients with hemoglobin Köln. CASE: A 36-year-old woman of Chinese origin with a twin pregnancy had an uneventful antenatal course except for the presence of thrombocytopenia that was not completely investigated. During elective repeat Caesarean section, it was noted that the woman had a low SpO2 on pulse oximetry despite a normal arterial oxygen tension from arterial blood gas measurement. Subsequent investigations identified the woman as a heterozygous carrier for hemoglobin Köln. CONCLUSION: Women with hemoglobin Köln who become pregnant require close monitoring of the maternal platelet count and an awareness of the falsely low SpO2 on pulse oximetry to ensure a favourable outcome. |
Persistent Identifier | http://hdl.handle.net/10722/173343 |
ISSN | 2023 Impact Factor: 2.0 2023 SCImago Journal Rankings: 0.611 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cheung, VY | en_US |
dc.contributor.author | Silverman, JA | en_US |
dc.date.accessioned | 2012-10-30T06:29:30Z | - |
dc.date.available | 2012-10-30T06:29:30Z | - |
dc.date.issued | 2008 | en_US |
dc.identifier.citation | Journal Of Obstetrics And Gynaecology Canada : Jogc = Journal D'obstétrique Et Gynécologie Du Canada : Jogc, 2008, v. 30 n. 10, p. 907-909 | en_US |
dc.identifier.issn | 1701-2163 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/173343 | - |
dc.description.abstract | BACKGROUND: Patients with hemoglobin Köln usually present with a mild hemolytic anemia characterized by reticulocytosis, splenomegaly, and elevated circulating bilirubin and lactate dehydrogenase levels. There have been no previous reports of whether these characteristics change during pregnancy and whether pregnancy provides any specific concerns for patients with hemoglobin Köln. CASE: A 36-year-old woman of Chinese origin with a twin pregnancy had an uneventful antenatal course except for the presence of thrombocytopenia that was not completely investigated. During elective repeat Caesarean section, it was noted that the woman had a low SpO2 on pulse oximetry despite a normal arterial oxygen tension from arterial blood gas measurement. Subsequent investigations identified the woman as a heterozygous carrier for hemoglobin Köln. CONCLUSION: Women with hemoglobin Köln who become pregnant require close monitoring of the maternal platelet count and an awareness of the falsely low SpO2 on pulse oximetry to ensure a favourable outcome. | en_US |
dc.language | eng | en_US |
dc.publisher | Canadian Medical Association. The Journal's web site is located at http://sogc.medical.org/JOGC/index_e.shtml | en_US |
dc.relation.ispartof | Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGC | en_US |
dc.subject | Hemoglobin Köln | - |
dc.subject | Hemoglobinopathy | - |
dc.subject | Low oxygen saturation | - |
dc.subject | Pregnancy | - |
dc.subject | Pulse oximetry | - |
dc.subject | Thrombocytopenia | - |
dc.subject | Unstable hemoglobin | - |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Carrier State | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Hemoglobins, Abnormal - Genetics | en_US |
dc.subject.mesh | Heterozygote | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Oximetry | en_US |
dc.subject.mesh | Oxygen - Blood | en_US |
dc.subject.mesh | Pregnancy | en_US |
dc.subject.mesh | Pregnancy Complications, Hematologic - Genetics | en_US |
dc.subject.mesh | Pregnancy, Multiple | en_US |
dc.subject.mesh | Thrombocytopenia - Genetics | en_US |
dc.subject.mesh | Twins | en_US |
dc.title | Hemoglobin köln and pregnancy. | en_US |
dc.type | Article | en_US |
dc.identifier.email | Cheung, VY:vytc@hku.hk | en_US |
dc.identifier.authority | Cheung, VY=rp01323 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.pmid | 19038075 | - |
dc.identifier.scopus | eid_2-s2.0-59649104695 | en_US |
dc.identifier.volume | 30 | en_US |
dc.identifier.issue | 10 | en_US |
dc.identifier.spage | 907 | en_US |
dc.identifier.epage | 909 | en_US |
dc.identifier.isi | WOS:000443030400008 | - |
dc.publisher.place | Canada | en_US |
dc.identifier.scopusauthorid | Cheung, VY=7005439023 | en_US |
dc.identifier.scopusauthorid | Silverman, JA=16208825800 | en_US |
dc.identifier.issnl | 1701-2163 | - |