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- Publisher Website: 10.1093/oxfordjournals.humrep.a138057
- Scopus: eid_2-s2.0-0027513493
- PMID: 8473453
- WOS: WOS:A1993KV69400010
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Article: A prospective randomized comparison of levonorgestrel with the Yuzpe regimen in post-coital contraception
Title | A prospective randomized comparison of levonorgestrel with the Yuzpe regimen in post-coital contraception |
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Authors | |
Keywords | Levonorgestrel Post-coital contraception Yuzpe |
Issue Date | 1993 |
Publisher | Oxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/ |
Citation | Human Reproduction, 1993, v. 8 n. 3, p. 389-392 How to Cite? |
Abstract | A prospective randomized study was conducted at the Family Planning Association of Hong Kong to compare the efficacy of the Yuzpe regimen and levonorgestrel (0.75 mg for two doses 12 h apart) in post-coital contraception. A total of 424 subjects were recruited into the Yuzpe group and 410 subjects into the levonorgestrel group; 77 subjects in the Yuzpe group and 79 subjects in the levonorgestrel group had further acts of intercourse during the treatment cycle. Fifteen pregnancies (3.5%) occurred in the Yuzpe group and 12 pregnancies (2.9%) in the levonorgestrel group. After excluding the patients who had further acts of intercourse, the failure rates in the Yuzpe group and the levonorgestrel group were 2.6 and 2.4% respectively. The incidence of nausea, vomiting and fatigue in the Yuzpe group was significantly higher than those in the levonorgestrel group. We conclude that levonorgestrel is an effective drug for post-coital contraception with a lower incidence of side-effects than the Yuzpe regimen. |
Persistent Identifier | http://hdl.handle.net/10722/173197 |
ISSN | 2023 Impact Factor: 6.0 2023 SCImago Journal Rankings: 1.852 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Ho, PC | en_US |
dc.contributor.author | Kwan, MSW | en_US |
dc.date.accessioned | 2012-10-30T06:28:27Z | - |
dc.date.available | 2012-10-30T06:28:27Z | - |
dc.date.issued | 1993 | en_US |
dc.identifier.citation | Human Reproduction, 1993, v. 8 n. 3, p. 389-392 | en_US |
dc.identifier.issn | 0268-1161 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/173197 | - |
dc.description.abstract | A prospective randomized study was conducted at the Family Planning Association of Hong Kong to compare the efficacy of the Yuzpe regimen and levonorgestrel (0.75 mg for two doses 12 h apart) in post-coital contraception. A total of 424 subjects were recruited into the Yuzpe group and 410 subjects into the levonorgestrel group; 77 subjects in the Yuzpe group and 79 subjects in the levonorgestrel group had further acts of intercourse during the treatment cycle. Fifteen pregnancies (3.5%) occurred in the Yuzpe group and 12 pregnancies (2.9%) in the levonorgestrel group. After excluding the patients who had further acts of intercourse, the failure rates in the Yuzpe group and the levonorgestrel group were 2.6 and 2.4% respectively. The incidence of nausea, vomiting and fatigue in the Yuzpe group was significantly higher than those in the levonorgestrel group. We conclude that levonorgestrel is an effective drug for post-coital contraception with a lower incidence of side-effects than the Yuzpe regimen. | en_US |
dc.language | eng | en_US |
dc.publisher | Oxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/ | en_US |
dc.relation.ispartof | Human Reproduction | en_US |
dc.subject | Levonorgestrel | - |
dc.subject | Post-coital contraception | - |
dc.subject | Yuzpe | - |
dc.subject.mesh | Adolescent | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Contraceptives, Postcoital - Therapeutic Use | en_US |
dc.subject.mesh | Drug Combinations | en_US |
dc.subject.mesh | Ethinyl Estradiol - Administration & Dosage - Adverse Effects - Therapeutic Use | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Hong Kong | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Levonorgestrel - Adverse Effects - Therapeutic Use | en_US |
dc.subject.mesh | Norgestrel - Administration & Dosage - Adverse Effects - Therapeutic Use | en_US |
dc.subject.mesh | Pregnancy | en_US |
dc.subject.mesh | Prospective Studies | en_US |
dc.title | A prospective randomized comparison of levonorgestrel with the Yuzpe regimen in post-coital contraception | en_US |
dc.type | Article | en_US |
dc.identifier.email | Ho, PC:pcho@hku.hk | en_US |
dc.identifier.authority | Ho, PC=rp00325 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1093/oxfordjournals.humrep.a138057 | - |
dc.identifier.pmid | 8473453 | - |
dc.identifier.scopus | eid_2-s2.0-0027513493 | en_US |
dc.identifier.volume | 8 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.spage | 389 | en_US |
dc.identifier.epage | 392 | en_US |
dc.identifier.isi | WOS:A1993KV69400010 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Ho, PC=7402211440 | en_US |
dc.identifier.scopusauthorid | Kwan, MSW=36860235800 | en_US |
dc.identifier.issnl | 0268-1161 | - |