File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Scopus: eid_2-s2.0-0027225387
- PMID: 8499089
- WOS: WOS:A1993LF78300002
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Regional chemotherapy for recurrent squamous head and neck cancers through a saphenous vein interposition graft
Title | Regional chemotherapy for recurrent squamous head and neck cancers through a saphenous vein interposition graft |
---|---|
Authors | |
Issue Date | 1993 |
Publisher | American Medical Association. The Journal's web site is located at http://www.archoto.com |
Citation | Archives Of Otolaryngology - Head And Neck Surgery, 1993, v. 119 n. 6, p. 608-611 How to Cite? |
Abstract | Regional chemotherapy for head and neck cancers is effective, but the intra-arterial catheter is not without problems. We interposed a segment of saphenous vein within the carotid system to administer chemotherapeutic agents percutaneously via the arterialized venous segment. From 1983 to 1990, saphenous vein interposition graft was performed after radiotherapy in 24 patients with persistent or recurrent squamous head and neck cancers, which were also considered unresectable. There was no operative mortality. Two patients developed thrombosed vein graft; another two had wound infection; and one patient had a neck hematoma. Cisplatin was administered percutaneously every week via the saphenous vein graft. The response rate was 64% (complete response, 23%; partial response, 41%), and the 5-year actuarial survival rate was 31%. The 1-year survival rates for patients with complete, partial, and no response were 80%, 33%, and 13%, respectively. Saphenous vein interposition graft is a safe and convenient way of delivering intra-arterial chemotherapy, and it provides significant palliation for patients with recurrent nonresectable squamous head and neck cancers after radiotherapy. |
Persistent Identifier | http://hdl.handle.net/10722/172689 |
ISSN | 2014 Impact Factor: 2.327 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ho, CM | en_US |
dc.contributor.author | Lam, LK | en_US |
dc.contributor.author | Wei, WI | en_US |
dc.contributor.author | Choi, TK | en_US |
dc.contributor.author | Lam, KH | en_US |
dc.date.accessioned | 2012-10-30T06:24:17Z | - |
dc.date.available | 2012-10-30T06:24:17Z | - |
dc.date.issued | 1993 | en_US |
dc.identifier.citation | Archives Of Otolaryngology - Head And Neck Surgery, 1993, v. 119 n. 6, p. 608-611 | en_US |
dc.identifier.issn | 0886-4470 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/172689 | - |
dc.description.abstract | Regional chemotherapy for head and neck cancers is effective, but the intra-arterial catheter is not without problems. We interposed a segment of saphenous vein within the carotid system to administer chemotherapeutic agents percutaneously via the arterialized venous segment. From 1983 to 1990, saphenous vein interposition graft was performed after radiotherapy in 24 patients with persistent or recurrent squamous head and neck cancers, which were also considered unresectable. There was no operative mortality. Two patients developed thrombosed vein graft; another two had wound infection; and one patient had a neck hematoma. Cisplatin was administered percutaneously every week via the saphenous vein graft. The response rate was 64% (complete response, 23%; partial response, 41%), and the 5-year actuarial survival rate was 31%. The 1-year survival rates for patients with complete, partial, and no response were 80%, 33%, and 13%, respectively. Saphenous vein interposition graft is a safe and convenient way of delivering intra-arterial chemotherapy, and it provides significant palliation for patients with recurrent nonresectable squamous head and neck cancers after radiotherapy. | en_US |
dc.language | eng | en_US |
dc.publisher | American Medical Association. The Journal's web site is located at http://www.archoto.com | en_US |
dc.relation.ispartof | Archives of Otolaryngology - Head and Neck Surgery | en_US |
dc.subject.mesh | Aged | en_US |
dc.subject.mesh | Aged, 80 And Over | en_US |
dc.subject.mesh | Anastomosis, Surgical | en_US |
dc.subject.mesh | Carcinoma, Squamous Cell - Complications - Drug Therapy - Mortality | en_US |
dc.subject.mesh | Carotid Artery, Common - Surgery | en_US |
dc.subject.mesh | Carotid Artery, External - Surgery | en_US |
dc.subject.mesh | Chemotherapy, Cancer, Regional Perfusion - Methods | en_US |
dc.subject.mesh | Cisplatin - Administration & Dosage - Adverse Effects | en_US |
dc.subject.mesh | Combined Modality Therapy | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Head And Neck Neoplasms - Complications - Drug Therapy - Mortality | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Neoplasm Recurrence, Local - Complications - Drug Therapy - Mortality | en_US |
dc.subject.mesh | Remission Induction | en_US |
dc.subject.mesh | Saphenous Vein - Transplantation | en_US |
dc.title | Regional chemotherapy for recurrent squamous head and neck cancers through a saphenous vein interposition graft | en_US |
dc.type | Article | en_US |
dc.identifier.email | Wei, WI: hrmswwi@hku.hk | en_US |
dc.identifier.authority | Wei, WI=rp00323 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.pmid | 8499089 | - |
dc.identifier.scopus | eid_2-s2.0-0027225387 | en_US |
dc.identifier.volume | 119 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.spage | 608 | en_US |
dc.identifier.epage | 611 | en_US |
dc.identifier.isi | WOS:A1993LF78300002 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Ho, CM=7404652540 | en_US |
dc.identifier.scopusauthorid | Lam, LK=7201984637 | en_US |
dc.identifier.scopusauthorid | Wei, WI=7403321552 | en_US |
dc.identifier.scopusauthorid | Choi, TK=7202770029 | en_US |
dc.identifier.scopusauthorid | Lam, KH=7403657342 | en_US |
dc.identifier.issnl | 0886-4470 | - |