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Article: Pre-operative parenteral nutrition in patients with oesophageal cancer: a prospective, randomised clinical trial
Title | Pre-operative parenteral nutrition in patients with oesophageal cancer: a prospective, randomised clinical trial |
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Authors | |
Issue Date | 1989 |
Publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/clnu |
Citation | Clinical Nutrition, 1989, v. 8 n. 1, p. 23-27 How to Cite? |
Abstract | A prospective randomised clinical trial was conducted to examine the efficacy of 2 weeks pre-operative parenteral nutrition (PPN) for the prevention of complications following surgery for oesophageal cancer. Forty patients were studied, the diet of twenty being supplemented by pre-operative parenteral nutrition. There were no significant differences in age, nutritional status, tumour staging and histology between the two groups of patients. The use of PPN resulted in a significant gain in body weight and nitrogen but failed to produce an overall reduction in post-operative morbidity and mortality rates. However patients receiving PPN exhibited two types of changes in serum albumin levels. Those with a fall in serum albumin levels associated with an increase in body weight (indicating an expansion of extracellular volume) had a significantly higher incidence of post-operative pulmonary complications than the group exhibiting a rise in serum albumin levels concomitant with increase in body weight. These data suggested that two weeks PPN might not be adequate in certain patients and a longer period of PPN is required. They also show no clinical benefit from the routine use of pre-operative parenteral nutrition in all patients, but do not exclude benefit in selected groups. |
Persistent Identifier | http://hdl.handle.net/10722/172603 |
ISSN | 2023 Impact Factor: 6.6 2023 SCImago Journal Rankings: 1.893 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Fan, ST | en_US |
dc.contributor.author | Lau, WY | en_US |
dc.contributor.author | Wong, KK | en_US |
dc.contributor.author | Chan, YPM | en_US |
dc.date.accessioned | 2012-10-30T06:23:41Z | - |
dc.date.available | 2012-10-30T06:23:41Z | - |
dc.date.issued | 1989 | en_US |
dc.identifier.citation | Clinical Nutrition, 1989, v. 8 n. 1, p. 23-27 | en_US |
dc.identifier.issn | 0261-5614 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/172603 | - |
dc.description.abstract | A prospective randomised clinical trial was conducted to examine the efficacy of 2 weeks pre-operative parenteral nutrition (PPN) for the prevention of complications following surgery for oesophageal cancer. Forty patients were studied, the diet of twenty being supplemented by pre-operative parenteral nutrition. There were no significant differences in age, nutritional status, tumour staging and histology between the two groups of patients. The use of PPN resulted in a significant gain in body weight and nitrogen but failed to produce an overall reduction in post-operative morbidity and mortality rates. However patients receiving PPN exhibited two types of changes in serum albumin levels. Those with a fall in serum albumin levels associated with an increase in body weight (indicating an expansion of extracellular volume) had a significantly higher incidence of post-operative pulmonary complications than the group exhibiting a rise in serum albumin levels concomitant with increase in body weight. These data suggested that two weeks PPN might not be adequate in certain patients and a longer period of PPN is required. They also show no clinical benefit from the routine use of pre-operative parenteral nutrition in all patients, but do not exclude benefit in selected groups. | en_US |
dc.language | eng | en_US |
dc.publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/clnu | en_US |
dc.relation.ispartof | Clinical Nutrition | en_US |
dc.title | Pre-operative parenteral nutrition in patients with oesophageal cancer: a prospective, randomised clinical trial | en_US |
dc.type | Article | en_US |
dc.identifier.email | Fan, ST: stfan@hku.hk | en_US |
dc.identifier.authority | Fan, ST=rp00355 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.scopus | eid_2-s2.0-0024502773 | en_US |
dc.identifier.volume | 8 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.spage | 23 | en_US |
dc.identifier.epage | 27 | en_US |
dc.identifier.isi | WOS:A1989T233500005 | - |
dc.publisher.place | Netherlands | en_US |
dc.identifier.scopusauthorid | Fan, ST=7402678224 | en_US |
dc.identifier.scopusauthorid | Lau, WY=7402933199 | en_US |
dc.identifier.scopusauthorid | Wong, KK=7404759210 | en_US |
dc.identifier.scopusauthorid | Chan, YPM=14009821700 | en_US |
dc.identifier.issnl | 0261-5614 | - |