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Article: Brain cholecystokin octopeptide (CCK-8) concentrations: Effect of tryptophan and other serotonergic agents

TitleBrain cholecystokin octopeptide (CCK-8) concentrations: Effect of tryptophan and other serotonergic agents
Authors
Chan, MYTang, F
Issue Date1994
PublisherChurchill Livingstone. The Journal's web site is located at http://www.elsevier.com/locate/npep
Citation
Neuropeptides, 1994, v. 26 n. 1, p. 59-63 How to Cite?
DOI: http://dx.doi.org/10.1016/0143-4179(94)90094-9
AbstractThe effects of 1-week drug treatment on the brain contents of neuropeptides were investigated. The cholecystokinin (CCK) concentrations in the hypothalamus were significantly decreased by tryptophan treatment but not by imipramine and cyproheptadine, which changed the serotonergic function. Proglumide, the CCK antagonist, induced in the hypothalamic and hippocampal-striatal areas an increase in CCK concentration, which was not reversed in the presence of tryptophan. Dynorphin and substance P(SP) concentrations were also modified by proglumide treatment.
Persistent Identifierhttp://hdl.handle.net/10722/171605
ISSN
0143-4179
2021 Impact Factor: 3.152
2020 SCImago Journal Rankings: 0.830
ISI Accession Number ID
WOS:A1994MQ30200009

 

DC FieldValueLanguage
dc.contributor.authorChan, MYen_US
dc.contributor.authorTang, Fen_US
dc.date.accessioned2012-10-30T06:15:56Z-
dc.date.available2012-10-30T06:15:56Z-
dc.date.issued1994en_US
dc.identifier.citationNeuropeptides, 1994, v. 26 n. 1, p. 59-63en_US
dc.identifier.issn0143-4179en_US
dc.identifier.urihttp://hdl.handle.net/10722/171605-
dc.description.abstractThe effects of 1-week drug treatment on the brain contents of neuropeptides were investigated. The cholecystokinin (CCK) concentrations in the hypothalamus were significantly decreased by tryptophan treatment but not by imipramine and cyproheptadine, which changed the serotonergic function. Proglumide, the CCK antagonist, induced in the hypothalamic and hippocampal-striatal areas an increase in CCK concentration, which was not reversed in the presence of tryptophan. Dynorphin and substance P(SP) concentrations were also modified by proglumide treatment.en_US
dc.languageengen_US
dc.publisherChurchill Livingstone. The Journal's web site is located at http://www.elsevier.com/locate/npepen_US
dc.relation.ispartofNeuropeptidesen_US
dc.titleBrain cholecystokin octopeptide (CCK-8) concentrations: Effect of tryptophan and other serotonergic agentsen_US
dc.typeArticleen_US
dc.identifier.emailTang, F:ftang@hkucc.hku.hken_US
dc.identifier.authorityTang, F=rp00327en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0143-4179(94)90094-9en_US
dc.identifier.pmid7512698-
dc.identifier.scopuseid_2-s2.0-0028180976en_US
dc.identifier.volume26en_US
dc.identifier.issue1en_US
dc.identifier.spage59en_US
dc.identifier.epage63en_US
dc.identifier.isiWOS:A1994MQ30200009-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridChan, MY=7402598142en_US
dc.identifier.scopusauthoridTang, F=7201979770en_US
dc.identifier.issnl0143-4179-

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