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Article: Retrospective study of vigabatrin and psychiatric behavioural disturbances

TitleRetrospective study of vigabatrin and psychiatric behavioural disturbances
Authors
KeywordsAdverse drug reactions
Retrospective study
Vigabatrin
Issue Date1995
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/epilepsyres
Citation
Epilepsy Research, 1995, v. 21 n. 3, p. 227-230 How to Cite?
AbstractVigabatrin (VGB) is an effective add-on anti-epileptic drug. The major serious adverse drug reactions (ADRs) are behavioural and psychiatric disturbances. This study does not support the view that a previous history of behavioural and psychiatric features increases the risk of behavioural/psychiatric ADRs (relative risk 1.23, 95% CI 0.57-2.66, P = 0.61). The results suggest that a low starting does of vigabatrin does not reduce the risk of psychiatric and behavioural ADRs (P = 0.31) or prevent a more overt psychotic reaction from occurring.
Persistent Identifierhttp://hdl.handle.net/10722/171169
ISSN
2020 Impact Factor: 3.045
2020 SCImago Journal Rankings: 0.863
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWong, ICKen_US
dc.date.accessioned2012-10-30T06:12:30Z-
dc.date.available2012-10-30T06:12:30Z-
dc.date.issued1995en_US
dc.identifier.citationEpilepsy Research, 1995, v. 21 n. 3, p. 227-230en_US
dc.identifier.issn0920-1211en_US
dc.identifier.urihttp://hdl.handle.net/10722/171169-
dc.description.abstractVigabatrin (VGB) is an effective add-on anti-epileptic drug. The major serious adverse drug reactions (ADRs) are behavioural and psychiatric disturbances. This study does not support the view that a previous history of behavioural and psychiatric features increases the risk of behavioural/psychiatric ADRs (relative risk 1.23, 95% CI 0.57-2.66, P = 0.61). The results suggest that a low starting does of vigabatrin does not reduce the risk of psychiatric and behavioural ADRs (P = 0.31) or prevent a more overt psychotic reaction from occurring.en_US
dc.languageengen_US
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/epilepsyresen_US
dc.relation.ispartofEpilepsy Researchen_US
dc.subjectAdverse drug reactions-
dc.subjectRetrospective study-
dc.subjectVigabatrin-
dc.titleRetrospective study of vigabatrin and psychiatric behavioural disturbancesen_US
dc.typeArticleen_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0920-1211(95)00022-3en_US
dc.identifier.pmid8536676-
dc.identifier.scopuseid_2-s2.0-0029094094en_US
dc.identifier.volume21en_US
dc.identifier.issue3en_US
dc.identifier.spage227en_US
dc.identifier.epage230en_US
dc.identifier.isiWOS:A1995RV90000006-
dc.publisher.placeNetherlandsen_US
dc.identifier.issnl0920-1211-

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