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- Publisher Website: 10.1161/01.CIR.80.1.1
- Scopus: eid_2-s2.0-0024312198
- PMID: 2661051
- WOS: WOS:A1989AE26700001
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Article: Endothelium-derived relaxing factor and coronary vasospasm
Title | Endothelium-derived relaxing factor and coronary vasospasm |
---|---|
Authors | |
Issue Date | 1989 |
Publisher | Lippincott Williams & Wilkins. The Journal's web site is located at http://circ.ahajournals.org |
Citation | Circulation, 1989, v. 80 n. 1, p. 1-9 How to Cite? |
Abstract | The endothelium releases the powerful vasodilator and antiaggregatory substance, EDRF, both under basal conditions and upon stimulation by a wide variety of agents. Endothelial injury or dysfunction may play an important role in the spasmogenicity of the coronary artery, although other possible alterations related to atherosclerosis should also be considered. Among the possible stimuli, aggregating platelets are important as a source of vasoconstrictor substances. The endothelium may also produce the vasoactive substances EDHF and EDCF(s). Their pathophysiologic significance remains to be determined. |
Persistent Identifier | http://hdl.handle.net/10722/170916 |
ISSN | 2023 Impact Factor: 35.5 2023 SCImago Journal Rankings: 8.415 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Vanhoutte, PM | en_US |
dc.contributor.author | Shimokawa, H | en_US |
dc.date.accessioned | 2012-10-30T06:11:25Z | - |
dc.date.available | 2012-10-30T06:11:25Z | - |
dc.date.issued | 1989 | en_US |
dc.identifier.citation | Circulation, 1989, v. 80 n. 1, p. 1-9 | en_US |
dc.identifier.issn | 0009-7322 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/170916 | - |
dc.description.abstract | The endothelium releases the powerful vasodilator and antiaggregatory substance, EDRF, both under basal conditions and upon stimulation by a wide variety of agents. Endothelial injury or dysfunction may play an important role in the spasmogenicity of the coronary artery, although other possible alterations related to atherosclerosis should also be considered. Among the possible stimuli, aggregating platelets are important as a source of vasoconstrictor substances. The endothelium may also produce the vasoactive substances EDHF and EDCF(s). Their pathophysiologic significance remains to be determined. | en_US |
dc.language | eng | en_US |
dc.publisher | Lippincott Williams & Wilkins. The Journal's web site is located at http://circ.ahajournals.org | en_US |
dc.relation.ispartof | Circulation | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Arteriosclerosis - Metabolism - Physiopathology | en_US |
dc.subject.mesh | Biological Factors - Metabolism - Physiology | en_US |
dc.subject.mesh | Blood Platelets - Physiology | en_US |
dc.subject.mesh | Coronary Vasospasm - Metabolism | en_US |
dc.subject.mesh | Endothelium, Vascular - Metabolism | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Nitric Oxide | en_US |
dc.subject.mesh | Vasoconstriction | en_US |
dc.title | Endothelium-derived relaxing factor and coronary vasospasm | en_US |
dc.type | Article | en_US |
dc.identifier.email | Vanhoutte, PM:vanhoutt@hku.hk | en_US |
dc.identifier.authority | Vanhoutte, PM=rp00238 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1161/01.CIR.80.1.1 | - |
dc.identifier.pmid | 2661051 | - |
dc.identifier.scopus | eid_2-s2.0-0024312198 | en_US |
dc.identifier.volume | 80 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.spage | 1 | en_US |
dc.identifier.epage | 9 | en_US |
dc.identifier.isi | WOS:A1989AE26700001 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Vanhoutte, PM=7202304247 | en_US |
dc.identifier.scopusauthorid | Shimokawa, H=16684837100 | en_US |
dc.identifier.issnl | 0009-7322 | - |