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- Publisher Website: 10.1097/00005344-198400061-00016
- Scopus: eid_2-s2.0-0021253503
- PMID: 6204164
- WOS: WOS:A1984SW38000015
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Article: Na+,K+-ATPase inhibitors and the adrenergic neuroeffector interaction in the blood vessel wall
Title | Na+,K+-ATPase inhibitors and the adrenergic neuroeffector interaction in the blood vessel wall |
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Authors | |
Keywords | Acetylstrophanthidin Cardenolides Endothelium Exocytotic release Monoamine oxidase Na+, K +-ATPase Neuronal uptake Norepinephrine Ouabain Postjunctional α-adrenoceptors |
Issue Date | 1984 |
Publisher | Lippincott Williams & Wilkins. The Journal's web site is located at http://www.cardiovascularpharm.com/ |
Citation | Journal Of Cardiovascular Pharmacology, 1984, v. 6 SUPPL. 1, p. S88-S94 How to Cite? |
Abstract | Augmentation of the constrictor response of blood vessels to sympathetic nerve stimulation caused by inhibitors of Na+,K+-ATPase can be explained by (a) inhibition of neuronal uptake, (b) displacement of stored norepinephrine, (c) facilitation of exocytotic release of the adrenergic transmitter, (d) diminution in intraneuronal deamination, (e) reduction in extraneuronal uptake, (f) facilitation of postjunctional α2-adrenoceptors, (g) inhibition of poststimulation relaxation, and, possibly, (h) prevention of endothelium-dependent relaxation. |
Persistent Identifier | http://hdl.handle.net/10722/170739 |
ISSN | 2023 Impact Factor: 2.6 2023 SCImago Journal Rankings: 0.610 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Vanhoutte, PM | en_US |
dc.contributor.author | Lorenz, RR | en_US |
dc.date.accessioned | 2012-10-30T06:10:39Z | - |
dc.date.available | 2012-10-30T06:10:39Z | - |
dc.date.issued | 1984 | en_US |
dc.identifier.citation | Journal Of Cardiovascular Pharmacology, 1984, v. 6 SUPPL. 1, p. S88-S94 | en_US |
dc.identifier.issn | 0160-2446 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/170739 | - |
dc.description.abstract | Augmentation of the constrictor response of blood vessels to sympathetic nerve stimulation caused by inhibitors of Na+,K+-ATPase can be explained by (a) inhibition of neuronal uptake, (b) displacement of stored norepinephrine, (c) facilitation of exocytotic release of the adrenergic transmitter, (d) diminution in intraneuronal deamination, (e) reduction in extraneuronal uptake, (f) facilitation of postjunctional α2-adrenoceptors, (g) inhibition of poststimulation relaxation, and, possibly, (h) prevention of endothelium-dependent relaxation. | en_US |
dc.language | eng | en_US |
dc.publisher | Lippincott Williams & Wilkins. The Journal's web site is located at http://www.cardiovascularpharm.com/ | en_US |
dc.relation.ispartof | Journal of Cardiovascular Pharmacology | en_US |
dc.subject | Acetylstrophanthidin | - |
dc.subject | Cardenolides | - |
dc.subject | Endothelium | - |
dc.subject | Exocytotic release | - |
dc.subject | Monoamine oxidase | - |
dc.subject | Na+, K +-ATPase | - |
dc.subject | Neuronal uptake | - |
dc.subject | Norepinephrine | - |
dc.subject | Ouabain | - |
dc.subject | Postjunctional α-adrenoceptors | - |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Dinoprost | en_US |
dc.subject.mesh | Dogs | en_US |
dc.subject.mesh | Endothelium - Drug Effects | en_US |
dc.subject.mesh | Hydroxydopamines - Pharmacology | en_US |
dc.subject.mesh | Muscle Relaxation - Drug Effects | en_US |
dc.subject.mesh | Muscle, Smooth, Vascular - Innervation - Physiology | en_US |
dc.subject.mesh | Neuroeffector Junction - Drug Effects | en_US |
dc.subject.mesh | Neurons - Metabolism | en_US |
dc.subject.mesh | Neurotransmitter Agents - Physiology | en_US |
dc.subject.mesh | Norepinephrine - Metabolism | en_US |
dc.subject.mesh | Ouabain - Pharmacology | en_US |
dc.subject.mesh | Oxidopamine | en_US |
dc.subject.mesh | Prostaglandins F - Pharmacology | en_US |
dc.subject.mesh | Receptors, Adrenergic, Alpha - Drug Effects | en_US |
dc.subject.mesh | Sodium-Potassium-Exchanging Atpase - Antagonists & Inhibitors | en_US |
dc.subject.mesh | Strophanthidin - Analogs & Derivatives - Pharmacology | en_US |
dc.subject.mesh | Sympathectomy, Chemical | en_US |
dc.subject.mesh | Sympathetic Nervous System - Drug Effects | en_US |
dc.title | Na+,K+-ATPase inhibitors and the adrenergic neuroeffector interaction in the blood vessel wall | en_US |
dc.type | Article | en_US |
dc.identifier.email | Vanhoutte, PM:vanhoutt@hku.hk | en_US |
dc.identifier.authority | Vanhoutte, PM=rp00238 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1097/00005344-198400061-00016 | - |
dc.identifier.pmid | 6204164 | - |
dc.identifier.scopus | eid_2-s2.0-0021253503 | en_US |
dc.identifier.volume | 6 | en_US |
dc.identifier.issue | SUPPL. 1 | en_US |
dc.identifier.spage | S88 | en_US |
dc.identifier.epage | S94 | en_US |
dc.identifier.isi | WOS:A1984SW38000015 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Vanhoutte, PM=7202304247 | en_US |
dc.identifier.scopusauthorid | Lorenz, RR=7402095192 | en_US |
dc.identifier.issnl | 0160-2446 | - |