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- Publisher Website: 10.1016/0014-2999(82)90063-2
- Scopus: eid_2-s2.0-0020054023
- PMID: 7106182
- WOS: WOS:A1982NS87400014
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Article: Non-neurogenic inhibitory effect of electrical impulses in isolated canine coronary arteries
Title | Non-neurogenic inhibitory effect of electrical impulses in isolated canine coronary arteries |
---|---|
Authors | |
Keywords | Coronary smooth muscle Electrical stimulation Inhibitory vasodilator nerves |
Issue Date | 1982 |
Publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/ejphar |
Citation | European Journal Of Pharmacology, 1982, v. 80 n. 2-3, p. 251-254 How to Cite? |
Abstract | Electrical stimulation caused frequency-dependent reversible relaxations of canine coronary arteries made to contract with prostaglandin F(2α), phenylephrine, 5-hydroxytryptamine, potassium chloride, or angiotensin II. These contractions were not affected by cold storage, tetrodotoxin, α- and β-adrenergic blockade and atropine, demonstrating that they probably are not due to activation of inhibitory nerves. The relaxation persisted in the presence of indomethacin and after removal of the endothelium. They were not seen in splenic arteries and saphenous veins, demonstrating the high sensitivity of the coronary blood vessel wall to the inhibitory effects of the electric impulses. |
Persistent Identifier | http://hdl.handle.net/10722/170677 |
ISSN | 2023 Impact Factor: 4.2 2023 SCImago Journal Rankings: 1.055 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Rooke, T | en_US |
dc.contributor.author | Cohen, RA | en_US |
dc.contributor.author | Verbeuren, TJ | en_US |
dc.contributor.author | Vanhoutte, PM | en_US |
dc.date.accessioned | 2012-10-30T06:10:24Z | - |
dc.date.available | 2012-10-30T06:10:24Z | - |
dc.date.issued | 1982 | en_US |
dc.identifier.citation | European Journal Of Pharmacology, 1982, v. 80 n. 2-3, p. 251-254 | en_US |
dc.identifier.issn | 0014-2999 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/170677 | - |
dc.description.abstract | Electrical stimulation caused frequency-dependent reversible relaxations of canine coronary arteries made to contract with prostaglandin F(2α), phenylephrine, 5-hydroxytryptamine, potassium chloride, or angiotensin II. These contractions were not affected by cold storage, tetrodotoxin, α- and β-adrenergic blockade and atropine, demonstrating that they probably are not due to activation of inhibitory nerves. The relaxation persisted in the presence of indomethacin and after removal of the endothelium. They were not seen in splenic arteries and saphenous veins, demonstrating the high sensitivity of the coronary blood vessel wall to the inhibitory effects of the electric impulses. | en_US |
dc.language | eng | en_US |
dc.publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/ejphar | en_US |
dc.relation.ispartof | European Journal of Pharmacology | en_US |
dc.subject | Coronary smooth muscle | - |
dc.subject | Electrical stimulation | - |
dc.subject | Inhibitory vasodilator nerves | - |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Coronary Vessels - Drug Effects - Innervation - Physiology | en_US |
dc.subject.mesh | Dogs | en_US |
dc.subject.mesh | Electric Stimulation | en_US |
dc.title | Non-neurogenic inhibitory effect of electrical impulses in isolated canine coronary arteries | en_US |
dc.type | Article | en_US |
dc.identifier.email | Vanhoutte, PM:vanhoutt@hku.hk | en_US |
dc.identifier.authority | Vanhoutte, PM=rp00238 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/0014-2999(82)90063-2 | - |
dc.identifier.pmid | 7106182 | - |
dc.identifier.scopus | eid_2-s2.0-0020054023 | en_US |
dc.identifier.volume | 80 | en_US |
dc.identifier.issue | 2-3 | en_US |
dc.identifier.spage | 251 | en_US |
dc.identifier.epage | 254 | en_US |
dc.identifier.isi | WOS:A1982NS87400014 | - |
dc.publisher.place | Netherlands | en_US |
dc.identifier.scopusauthorid | Rooke, T=8757981200 | en_US |
dc.identifier.scopusauthorid | Cohen, RA=35562815800 | en_US |
dc.identifier.scopusauthorid | Verbeuren, TJ=7007006534 | en_US |
dc.identifier.scopusauthorid | Vanhoutte, PM=7202304247 | en_US |
dc.identifier.issnl | 0014-2999 | - |