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- Publisher Website: 10.1042/cs057233s
- Scopus: eid_2-s2.0-0018636650
- PMID: 540438
- WOS: WOS:A1979JG73600059
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Article: Enhanced release of noradrenaline in the kidney of the young spontaneously hypertensive rat
Title | Enhanced release of noradrenaline in the kidney of the young spontaneously hypertensive rat |
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Authors | |
Issue Date | 1979 |
Publisher | Portland Press Ltd. The Journal's web site is located at http://www.clinsci.org/ |
Citation | Clinical Science, 1979, v. 57 SUPPL. 5, p. 233-234 How to Cite? |
Abstract | Vascular reactivity and noradrenaline overflow were studied in Tyrode solution-perfused kidneys from young (6 weeks) normotensive and spontaneously hypertensive (SH) rats. The vasoconstrictor response to nerve stimulation was greater in the kidneys from young SH rats than in those from young control rats. Nerve stimulation evoked a greater release of noradrenaline in the kidneys from young SH rats than in those from normotensive animals. The results demonstrate that the renal sympathetic nerves release more noradrenaline than normal in the young SH rats, which could be an important factor in causing hypertension. |
Persistent Identifier | http://hdl.handle.net/10722/170592 |
ISSN | 2021 Impact Factor: 6.876 2020 SCImago Journal Rankings: 1.910 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Collis, MG | en_US |
dc.contributor.author | De Mey, C | en_US |
dc.contributor.author | Vanhoutte, PM | en_US |
dc.date.accessioned | 2012-10-30T06:10:04Z | - |
dc.date.available | 2012-10-30T06:10:04Z | - |
dc.date.issued | 1979 | en_US |
dc.identifier.citation | Clinical Science, 1979, v. 57 SUPPL. 5, p. 233-234 | en_US |
dc.identifier.issn | 0143-5221 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/170592 | - |
dc.description.abstract | Vascular reactivity and noradrenaline overflow were studied in Tyrode solution-perfused kidneys from young (6 weeks) normotensive and spontaneously hypertensive (SH) rats. The vasoconstrictor response to nerve stimulation was greater in the kidneys from young SH rats than in those from young control rats. Nerve stimulation evoked a greater release of noradrenaline in the kidneys from young SH rats than in those from normotensive animals. The results demonstrate that the renal sympathetic nerves release more noradrenaline than normal in the young SH rats, which could be an important factor in causing hypertension. | en_US |
dc.language | eng | en_US |
dc.publisher | Portland Press Ltd. The Journal's web site is located at http://www.clinsci.org/ | en_US |
dc.relation.ispartof | Clinical Science | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Blood Pressure | en_US |
dc.subject.mesh | Hypertension - Metabolism - Physiopathology | en_US |
dc.subject.mesh | Kidney - Innervation - Metabolism | en_US |
dc.subject.mesh | Norepinephrine - Metabolism | en_US |
dc.subject.mesh | Rats | en_US |
dc.subject.mesh | Sympathetic Nervous System - Physiology - Physiopathology | en_US |
dc.title | Enhanced release of noradrenaline in the kidney of the young spontaneously hypertensive rat | en_US |
dc.type | Article | en_US |
dc.identifier.email | Vanhoutte, PM:vanhoutt@hku.hk | en_US |
dc.identifier.authority | Vanhoutte, PM=rp00238 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1042/cs057233s | - |
dc.identifier.pmid | 540438 | - |
dc.identifier.scopus | eid_2-s2.0-0018636650 | en_US |
dc.identifier.volume | 57 | en_US |
dc.identifier.issue | SUPPL. 5 | en_US |
dc.identifier.spage | 233 | en_US |
dc.identifier.epage | 234 | en_US |
dc.identifier.isi | WOS:A1979JG73600059 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Collis, MG=7005797278 | en_US |
dc.identifier.scopusauthorid | De Mey, C=7006663615 | en_US |
dc.identifier.scopusauthorid | Vanhoutte, PM=7202304247 | en_US |
dc.identifier.issnl | 0143-5221 | - |