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Article: Acetylcholine-inhibition of transmitter release from adrenergic nerve terminals mediated by muscarinic receptors

TitleAcetylcholine-inhibition of transmitter release from adrenergic nerve terminals mediated by muscarinic receptors
Authors
Shepherd, JTLorenz, RRTyce, GMVanhoutte, PM
Issue Date1978
Citation
Federation Proceedings, 1978, v. 37 n. 2, p. 191-194 How to Cite?
AbstractThe evidence is reviewed for the presence of muscarinic receptors on the sympathetic nerves to blood vessels. Activation of these receptors by acetylcholine in doses that are too small to affect the smooth muscle cells directly inhibits the release of norepinpherine evoked by electric impulses or potassium ions. This inhibitory action of acetylcholine is prevented by muscarinic blocking agents and is probably due to hyperpolarization of the adrenergic nerve terminals.
Persistent Identifierhttp://hdl.handle.net/10722/170544
ISSN
0014-9446
ISI Accession Number ID
WOS:A1978ER63000020

 

DC FieldValueLanguage
dc.contributor.authorShepherd, JTen_US
dc.contributor.authorLorenz, RRen_US
dc.contributor.authorTyce, GMen_US
dc.contributor.authorVanhoutte, PMen_US
dc.date.accessioned2012-10-30T06:09:52Z-
dc.date.available2012-10-30T06:09:52Z-
dc.date.issued1978en_US
dc.identifier.citationFederation Proceedings, 1978, v. 37 n. 2, p. 191-194en_US
dc.identifier.issn0014-9446en_US
dc.identifier.urihttp://hdl.handle.net/10722/170544-
dc.description.abstractThe evidence is reviewed for the presence of muscarinic receptors on the sympathetic nerves to blood vessels. Activation of these receptors by acetylcholine in doses that are too small to affect the smooth muscle cells directly inhibits the release of norepinpherine evoked by electric impulses or potassium ions. This inhibitory action of acetylcholine is prevented by muscarinic blocking agents and is probably due to hyperpolarization of the adrenergic nerve terminals.en_US
dc.languageengen_US
dc.relation.ispartofFederation Proceedingsen_US
dc.subject.meshAcetylcholine - Pharmacologyen_US
dc.subject.meshAdrenergic Fibers - Secretionen_US
dc.subject.meshAnimalsen_US
dc.subject.meshDogsen_US
dc.subject.meshMuscle, Smooth - Innervationen_US
dc.subject.meshNeurotransmitter Agents - Secretionen_US
dc.subject.meshNorepinephrine - Antagonists & Inhibitorsen_US
dc.subject.meshPotassium - Metabolismen_US
dc.subject.meshReceptors, Cholinergic - Metabolismen_US
dc.subject.meshReceptors, Muscarinic - Metabolismen_US
dc.subject.meshSaphenous Vein - Innervationen_US
dc.titleAcetylcholine-inhibition of transmitter release from adrenergic nerve terminals mediated by muscarinic receptorsen_US
dc.typeArticleen_US
dc.identifier.emailVanhoutte, PM:vanhoutt@hku.hken_US
dc.identifier.authorityVanhoutte, PM=rp00238en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid23965-
dc.identifier.scopuseid_2-s2.0-0017833965en_US
dc.identifier.volume37en_US
dc.identifier.issue2en_US
dc.identifier.spage191en_US
dc.identifier.epage194en_US
dc.identifier.isiWOS:A1978ER63000020-
dc.identifier.scopusauthoridShepherd, JT=7401742522en_US
dc.identifier.scopusauthoridLorenz, RR=7402095192en_US
dc.identifier.scopusauthoridTyce, GM=7004909546en_US
dc.identifier.scopusauthoridVanhoutte, PM=7202304247en_US
dc.identifier.issnl0014-9446-

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