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- Scopus: eid_2-s2.0-0017063260
- PMID: 962442
- WOS: WOS:A1976BV68400020
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Article: Acetylcholine inhibits potassium evoked release of 3H norepinephrine in different blood vessels of the dog
Title | Acetylcholine inhibits potassium evoked release of 3H norepinephrine in different blood vessels of the dog |
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Authors | |
Issue Date | 1976 |
Citation | Archives Internationales De Pharmacodynamie Et De Therapie, 1976, v. 221 n. 2, p. 347-350 How to Cite? |
Abstract | The present experiments were designed to investigate whether acetylcholine affects the responsiveness of blood vessels to K+. Helical strips of saphenous veins and of pulmonary and tibial arteries, and longitudinal strips of mesenteric veins were studied in an organ chamber at 37°C; changes in isometric tension were recorded. The present experiments indicate that acetylcholine inhibits the release of adrenergic neurotransmitter caused by depolarization of the nerve endings in different blood vessel preparations, as it does during nerve stimulation. |
Persistent Identifier | http://hdl.handle.net/10722/170511 |
ISSN | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Verbeuren, TJ | en_US |
dc.contributor.author | Vanhoutte, PM | en_US |
dc.date.accessioned | 2012-10-30T06:09:45Z | - |
dc.date.available | 2012-10-30T06:09:45Z | - |
dc.date.issued | 1976 | en_US |
dc.identifier.citation | Archives Internationales De Pharmacodynamie Et De Therapie, 1976, v. 221 n. 2, p. 347-350 | en_US |
dc.identifier.issn | 0003-9780 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/170511 | - |
dc.description.abstract | The present experiments were designed to investigate whether acetylcholine affects the responsiveness of blood vessels to K+. Helical strips of saphenous veins and of pulmonary and tibial arteries, and longitudinal strips of mesenteric veins were studied in an organ chamber at 37°C; changes in isometric tension were recorded. The present experiments indicate that acetylcholine inhibits the release of adrenergic neurotransmitter caused by depolarization of the nerve endings in different blood vessel preparations, as it does during nerve stimulation. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Archives Internationales de Pharmacodynamie et de Therapie | en_US |
dc.subject.mesh | Acetylcholine - Pharmacology | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Blood Vessels - Drug Effects - Metabolism | en_US |
dc.subject.mesh | Depression, Chemical | en_US |
dc.subject.mesh | Dogs | en_US |
dc.subject.mesh | Mesenteric Veins - Metabolism | en_US |
dc.subject.mesh | Norepinephrine - Antagonists & Inhibitors - Metabolism | en_US |
dc.subject.mesh | Potassium - Pharmacology | en_US |
dc.subject.mesh | Pulmonary Artery - Drug Effects | en_US |
dc.subject.mesh | Regional Blood Flow - Drug Effects | en_US |
dc.subject.mesh | Saphenous Vein - Drug Effects | en_US |
dc.subject.mesh | Tibia - Blood Supply | en_US |
dc.title | Acetylcholine inhibits potassium evoked release of 3H norepinephrine in different blood vessels of the dog | en_US |
dc.type | Article | en_US |
dc.identifier.email | Vanhoutte, PM:vanhoutt@hku.hk | en_US |
dc.identifier.authority | Vanhoutte, PM=rp00238 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.pmid | 962442 | - |
dc.identifier.scopus | eid_2-s2.0-0017063260 | en_US |
dc.identifier.volume | 221 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.spage | 347 | en_US |
dc.identifier.epage | 350 | en_US |
dc.identifier.isi | WOS:A1976BV68400020 | - |
dc.identifier.scopusauthorid | Verbeuren, TJ=7007006534 | en_US |
dc.identifier.scopusauthorid | Vanhoutte, PM=7202304247 | en_US |
dc.identifier.issnl | 0003-9780 | - |