File Download
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1038/cmi.2009.51
- Scopus: eid_2-s2.0-73649095879
- PMID: 20003815
- WOS: WOS:000274324300001
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Primary immunodeficiencies: "New" disease in an old country
Title | Primary immunodeficiencies: "New" disease in an old country |
---|---|
Authors | |
Keywords | China Development Immunodeficiencies Primary immunodeficiency disorders Research |
Issue Date | 2009 |
Publisher | Chinese Society of Immunology. The Journal's web site is located at http://www.nature.com/cmi/index.html |
Citation | Cellular And Molecular Immunology, 2009, v. 6 n. 6, p. 397-406 How to Cite? |
Abstract | Primary immunodeficiency disorders (PIDs) are rare inborn errors of the immune system. Patients with PIDs are unique models that exemplify the functional and phenotypic consequences of various immune defects underlying infections, autoimmunity, lymphoproliferation, allergy and cancer. Over 150 PID syndromes were characterized in the past 60 years, with an ever growing list of new entities being discovered. Because of their rarity, multi-center collaboration for pooled data analysis and molecular studies is important to gain meaningful insights into the phenotypic and genetic diversities of PIDs. In this article, we summarize our research findings on PIDs in Chinese population in the past 20 years. Close collaboration among various immunology centers, cross-referrals and systematic data analysis constitute the foundation for research on PIDs. Future directions include establishment of a national PID registry, raising awareness of PIDs and securing sufficient resources for patient care and scientific research. ©2009 Chinese Society of Immunology and University of Science & Technology of China. |
Persistent Identifier | http://hdl.handle.net/10722/170430 |
ISSN | 2023 Impact Factor: 21.8 2023 SCImago Journal Rankings: 4.838 |
PubMed Central ID | |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, PPW | en_US |
dc.contributor.author | Lau, YL | en_US |
dc.date.accessioned | 2012-10-30T06:08:28Z | - |
dc.date.available | 2012-10-30T06:08:28Z | - |
dc.date.issued | 2009 | en_US |
dc.identifier.citation | Cellular And Molecular Immunology, 2009, v. 6 n. 6, p. 397-406 | en_US |
dc.identifier.issn | 1672-7681 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/170430 | - |
dc.description.abstract | Primary immunodeficiency disorders (PIDs) are rare inborn errors of the immune system. Patients with PIDs are unique models that exemplify the functional and phenotypic consequences of various immune defects underlying infections, autoimmunity, lymphoproliferation, allergy and cancer. Over 150 PID syndromes were characterized in the past 60 years, with an ever growing list of new entities being discovered. Because of their rarity, multi-center collaboration for pooled data analysis and molecular studies is important to gain meaningful insights into the phenotypic and genetic diversities of PIDs. In this article, we summarize our research findings on PIDs in Chinese population in the past 20 years. Close collaboration among various immunology centers, cross-referrals and systematic data analysis constitute the foundation for research on PIDs. Future directions include establishment of a national PID registry, raising awareness of PIDs and securing sufficient resources for patient care and scientific research. ©2009 Chinese Society of Immunology and University of Science & Technology of China. | en_US |
dc.language | eng | en_US |
dc.publisher | Chinese Society of Immunology. The Journal's web site is located at http://www.nature.com/cmi/index.html | en_US |
dc.relation.ispartof | Cellular and Molecular Immunology | en_US |
dc.subject | China | - |
dc.subject | Development | - |
dc.subject | Immunodeficiencies | - |
dc.subject | Primary immunodeficiency disorders | - |
dc.subject | Research | - |
dc.subject.mesh | China - Epidemiology | en_US |
dc.subject.mesh | Genetic Testing | en_US |
dc.subject.mesh | Genetic Variation | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Immunologic Deficiency Syndromes - Epidemiology - Genetics - Immunology | en_US |
dc.subject.mesh | Sociology, Medical | en_US |
dc.title | Primary immunodeficiencies: "New" disease in an old country | en_US |
dc.type | Article | en_US |
dc.identifier.email | Lee, PPW:ppwlee@hku.hk | en_US |
dc.identifier.email | Lau, YL:lauylung@hkucc.hku.hk | en_US |
dc.identifier.authority | Lee, PPW=rp00462 | en_US |
dc.identifier.authority | Lau, YL=rp00361 | en_US |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1038/cmi.2009.51 | en_US |
dc.identifier.pmid | 20003815 | - |
dc.identifier.pmcid | PMC4003033 | - |
dc.identifier.scopus | eid_2-s2.0-73649095879 | en_US |
dc.identifier.hkuros | 170387 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-73649095879&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 6 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.spage | 397 | en_US |
dc.identifier.epage | 406 | en_US |
dc.identifier.isi | WOS:000274324300001 | - |
dc.publisher.place | China | en_US |
dc.identifier.scopusauthorid | Lee, PPW=14048822200 | en_US |
dc.identifier.scopusauthorid | Lau, YL=7201403380 | en_US |
dc.identifier.issnl | 1672-7681 | - |