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- Publisher Website: 10.1039/b503535j
- Scopus: eid_2-s2.0-27644475402
- PMID: 16010318
- WOS: WOS:000230399400010
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Article: Physiologically stable vanadium(IV) porphyrins as a new class of anti-HIV agents
Title | Physiologically stable vanadium(IV) porphyrins as a new class of anti-HIV agents |
---|---|
Authors | |
Issue Date | 2005 |
Publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp |
Citation | Chemical Communications, 2005 n. 28, p. 3544-3546 How to Cite? |
Abstract | The water soluble oxovanadium(IV) tetraarylporphyrin 1a has demonstrated excellent solution stability against glutathione reduction and high potency (5 μM, 97% inhibition) in inhibiting HIV-1 replication in Hut/CCR5 cells. © The Royal Society of Chemistry 2005. |
Persistent Identifier | http://hdl.handle.net/10722/167966 |
ISSN | 2023 Impact Factor: 4.3 2023 SCImago Journal Rankings: 1.133 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Wong, SY | en_US |
dc.contributor.author | Sun, RWY | en_US |
dc.contributor.author | Chung, NPY | en_US |
dc.contributor.author | Lin, CL | en_US |
dc.contributor.author | Che, CM | en_US |
dc.date.accessioned | 2012-10-08T03:13:32Z | - |
dc.date.available | 2012-10-08T03:13:32Z | - |
dc.date.issued | 2005 | en_US |
dc.identifier.citation | Chemical Communications, 2005 n. 28, p. 3544-3546 | en_US |
dc.identifier.issn | 1359-7345 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/167966 | - |
dc.description.abstract | The water soluble oxovanadium(IV) tetraarylporphyrin 1a has demonstrated excellent solution stability against glutathione reduction and high potency (5 μM, 97% inhibition) in inhibiting HIV-1 replication in Hut/CCR5 cells. © The Royal Society of Chemistry 2005. | en_US |
dc.language | eng | en_US |
dc.publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp | en_US |
dc.relation.ispartof | Chemical Communications | en_US |
dc.subject.mesh | Anti-Hiv Agents - Chemistry - Pharmacology | en_US |
dc.subject.mesh | Cell Line | en_US |
dc.subject.mesh | Dose-Response Relationship, Drug | en_US |
dc.subject.mesh | Drug Stability | en_US |
dc.subject.mesh | Glutathione - Metabolism | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Metalloporphyrins - Chemistry - Pharmacology | en_US |
dc.subject.mesh | Oxidation-Reduction | en_US |
dc.subject.mesh | Receptors, Ccr5 | en_US |
dc.subject.mesh | Solubility | en_US |
dc.subject.mesh | Vanadium Compounds - Chemistry - Pharmacology | en_US |
dc.subject.mesh | Virus Replication - Drug Effects | en_US |
dc.title | Physiologically stable vanadium(IV) porphyrins as a new class of anti-HIV agents | en_US |
dc.type | Article | en_US |
dc.identifier.email | Sun, RWY:rwysun@hku.hk | en_US |
dc.identifier.email | Che, CM:cmche@hku.hk | en_US |
dc.identifier.authority | Sun, RWY=rp00781 | en_US |
dc.identifier.authority | Che, CM=rp00670 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1039/b503535j | en_US |
dc.identifier.pmid | 16010318 | - |
dc.identifier.scopus | eid_2-s2.0-27644475402 | en_US |
dc.identifier.hkuros | 117879 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-27644475402&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.issue | 28 | en_US |
dc.identifier.spage | 3544 | en_US |
dc.identifier.epage | 3546 | en_US |
dc.identifier.isi | WOS:000230399400010 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Wong, SY=24582723200 | en_US |
dc.identifier.scopusauthorid | Sun, RWY=26325835800 | en_US |
dc.identifier.scopusauthorid | Chung, NPY=9271796700 | en_US |
dc.identifier.scopusauthorid | Lin, CL=49763478200 | en_US |
dc.identifier.scopusauthorid | Che, CM=7102442791 | en_US |
dc.identifier.issnl | 1359-7345 | - |