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- Publisher Website: 10.1016/j.bpobgyn.2012.05.004
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- PMID: 22703626
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Article: Management of anovulatory infertility
Title | Management of anovulatory infertility |
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Authors | |
Keywords | Anovulatory Subfertility Anti-Oestrogen Aromatase Inhibitor Dopamine Agonist Gonadotrophin Ovarian Drilling Pulsatile Gnrh Weight Management |
Issue Date | 2012 |
Publisher | Bailliere Tindall. The Journal's web site is located at http://www.elsevier.com/locate/bpobgyn |
Citation | Bailliere's Best Practice And Research In Clinical Obstetrics And Gynaecology, 2012, v. 26 n. 6, p. 757-768 How to Cite? |
Abstract | Anovulatory subfertility is a heterogeneous condition with various underlying causes, which should be identified with appropriate history taking, physical examination and relevant investigations. Optimisation of body weight is essential in either underweight, overweight or obese individuals. Women with hypogonadotrophic anovulation can be treated with pulsatile gonadotrophin-releasing hormone therapy or a gonadotrophin preparation containing both follicle-stimulating hormone or luteinising hormone activities. For normogonadotrophic anovulation, clomiphene citrate should be used as first-line medical treatment. Metformin co-treatment with clomiphene citrate may be considered in a subgroup of women with polycystic ovary syndrome who are obese or clomiphene-resistant. Ovulation induction with gonadotrophin or laparoscopic ovarian drilling is the next option. Dopamine agonist is indicated for anovulation as a result of hyperprolactinaemia. © 2012 Elsevier Ltd. All rights reserved. |
Persistent Identifier | http://hdl.handle.net/10722/167096 |
ISSN | 2023 Impact Factor: 3.9 2023 SCImago Journal Rankings: 1.532 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Li, RHW | en_US |
dc.contributor.author | Ng, EHY | en_US |
dc.date.accessioned | 2012-09-28T04:03:40Z | - |
dc.date.available | 2012-09-28T04:03:40Z | - |
dc.date.issued | 2012 | en_US |
dc.identifier.citation | Bailliere's Best Practice And Research In Clinical Obstetrics And Gynaecology, 2012, v. 26 n. 6, p. 757-768 | en_US |
dc.identifier.issn | 1521-6934 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/167096 | - |
dc.description.abstract | Anovulatory subfertility is a heterogeneous condition with various underlying causes, which should be identified with appropriate history taking, physical examination and relevant investigations. Optimisation of body weight is essential in either underweight, overweight or obese individuals. Women with hypogonadotrophic anovulation can be treated with pulsatile gonadotrophin-releasing hormone therapy or a gonadotrophin preparation containing both follicle-stimulating hormone or luteinising hormone activities. For normogonadotrophic anovulation, clomiphene citrate should be used as first-line medical treatment. Metformin co-treatment with clomiphene citrate may be considered in a subgroup of women with polycystic ovary syndrome who are obese or clomiphene-resistant. Ovulation induction with gonadotrophin or laparoscopic ovarian drilling is the next option. Dopamine agonist is indicated for anovulation as a result of hyperprolactinaemia. © 2012 Elsevier Ltd. All rights reserved. | en_US |
dc.language | eng | en_US |
dc.publisher | Bailliere Tindall. The Journal's web site is located at http://www.elsevier.com/locate/bpobgyn | en_US |
dc.relation.ispartof | Bailliere's Best Practice and Research in Clinical Obstetrics and Gynaecology | en_US |
dc.rights | NOTICE: this is the author’s version of a work that was accepted for publication in Bailliere's Best Practice And Research In Clinical Obstetrics And Gynaecology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Bailliere's Best Practice And Research In Clinical Obstetrics And Gynaecology, 2012, v. 26 n. 6, p. 757-768. DOI: 10.1016/j.bpobgyn.2012.05.004 | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Anovulatory Subfertility | en_US |
dc.subject | Anti-Oestrogen | en_US |
dc.subject | Aromatase Inhibitor | en_US |
dc.subject | Dopamine Agonist | en_US |
dc.subject | Gonadotrophin | en_US |
dc.subject | Ovarian Drilling | en_US |
dc.subject | Pulsatile Gnrh | en_US |
dc.subject | Weight Management | en_US |
dc.title | Management of anovulatory infertility | en_US |
dc.type | Article | en_US |
dc.identifier.email | Li, RHW: raymondli@hku.hk | en_US |
dc.identifier.email | Ng, EHY: nghye@hku.hk | en_US |
dc.identifier.authority | Li, RHW=rp01649 | en_US |
dc.identifier.authority | Ng, EHY=rp00426 | en_US |
dc.description.nature | postprint | en_US |
dc.identifier.doi | 10.1016/j.bpobgyn.2012.05.004 | en_US |
dc.identifier.pmid | 22703626 | - |
dc.identifier.scopus | eid_2-s2.0-84867891189 | en_US |
dc.identifier.hkuros | 222175 | - |
dc.identifier.isi | WOS:000310948000005 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Li, RHW=7404724295 | en_US |
dc.identifier.scopusauthorid | Ng, EHY=35238184300 | en_US |
dc.identifier.issnl | 1521-6934 | - |