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- Publisher Website: 10.1016/S0140-6736(02)11030-0
- Scopus: eid_2-s2.0-0037152074
- PMID: 12354485
- WOS: WOS:000178142200022
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Conference Paper: Peptic-ulcer disease
Title | Peptic-ulcer disease |
---|---|
Authors | |
Issue Date | 2002 |
Publisher | The Lancet Publishing Group. The Journal's web site is located at http://www.elsevier.com/locate/lancet |
Citation | Lancet, 2002, v. 360 n. 9337, p. 933-941 How to Cite? |
Abstract | The discovery of Helicobacter pylori has greatly changed our approach to peptic ulcer disease. Bacterial, host, and environmental factors all have a role in peptic-ulcer disease. Although the prevalence of uncomplicated peptic ulcers is falling, hospital admissions for ulcer complications associated with non-steroidal anti-inflammatory drugs (NSAIDs) are rising. Evidence suggests that coprescription of NSAIDs with potent antiulcer agents and the use of highly selective cyclo-oxygenase-2 inhibitors reduce gastroduodenal ulceration. Whether these therapeutic advances will translate into clinical benefits remains to be seen. The interaction between H pylori and NSAIDs is one of the most controversial issues in peptic ulcer disease. With the fall in rates of H pylori infection, the proportion of ulcers not related to this organism and NSAIDs has risen, which will affect the management of peptic ulcer. |
Persistent Identifier | http://hdl.handle.net/10722/163554 |
ISSN | 2021 Impact Factor: 202.731 2020 SCImago Journal Rankings: 13.103 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chan, FKL | en_US |
dc.contributor.author | Leung, WK | en_US |
dc.date.accessioned | 2012-09-05T05:37:22Z | - |
dc.date.available | 2012-09-05T05:37:22Z | - |
dc.date.issued | 2002 | en_US |
dc.identifier.citation | Lancet, 2002, v. 360 n. 9337, p. 933-941 | en_US |
dc.identifier.issn | 0140-6736 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/163554 | - |
dc.description.abstract | The discovery of Helicobacter pylori has greatly changed our approach to peptic ulcer disease. Bacterial, host, and environmental factors all have a role in peptic-ulcer disease. Although the prevalence of uncomplicated peptic ulcers is falling, hospital admissions for ulcer complications associated with non-steroidal anti-inflammatory drugs (NSAIDs) are rising. Evidence suggests that coprescription of NSAIDs with potent antiulcer agents and the use of highly selective cyclo-oxygenase-2 inhibitors reduce gastroduodenal ulceration. Whether these therapeutic advances will translate into clinical benefits remains to be seen. The interaction between H pylori and NSAIDs is one of the most controversial issues in peptic ulcer disease. With the fall in rates of H pylori infection, the proportion of ulcers not related to this organism and NSAIDs has risen, which will affect the management of peptic ulcer. | en_US |
dc.language | eng | en_US |
dc.publisher | The Lancet Publishing Group. The Journal's web site is located at http://www.elsevier.com/locate/lancet | en_US |
dc.relation.ispartof | Lancet | en_US |
dc.subject.mesh | Anti-Inflammatory Agents, Non-Steroidal - Adverse Effects | en_US |
dc.subject.mesh | Anti-Ulcer Agents - Therapeutic Use | en_US |
dc.subject.mesh | Clinical Trials As Topic | en_US |
dc.subject.mesh | Helicobacter Infections - Drug Therapy - Physiopathology | en_US |
dc.subject.mesh | Helicobacter Pylori | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Peptic Ulcer - Drug Therapy - Microbiology - Physiopathology | en_US |
dc.title | Peptic-ulcer disease | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Leung, WK:waikleung@hku.hk | en_US |
dc.identifier.authority | Leung, WK=rp01479 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/S0140-6736(02)11030-0 | en_US |
dc.identifier.pmid | 12354485 | - |
dc.identifier.scopus | eid_2-s2.0-0037152074 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0037152074&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 360 | en_US |
dc.identifier.issue | 9337 | en_US |
dc.identifier.spage | 933 | en_US |
dc.identifier.epage | 941 | en_US |
dc.identifier.isi | WOS:000178142200022 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Chan, FKL=7202586434 | en_US |
dc.identifier.scopusauthorid | Leung, WK=7201504523 | en_US |
dc.identifier.issnl | 0140-6736 | - |