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Article: The effect of a deproteinized bovine bone mineral on bone regeneration around titanium dental implants

TitleThe effect of a deproteinized bovine bone mineral on bone regeneration around titanium dental implants
Authors
KeywordsAnimal
Bone formation
Bone graft
Deproteinized bovine bone
ePTFE membrane
Guided tissue regeneration
Jaw bone
Osteoconductivity index
Issue Date1998
PublisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLR
Citation
Clinical Oral Implants Research, 1998, v. 9 n. 3, p. 151-162 How to Cite?
AbstractThe aim of the present experiment was to test the effect of a deproteinized bovine bone mineral (Bio-Oss®) on guided bone regeneration (GBR) in dehiscence defects around implants. The first 2 molars and all premolars were extracted on both sides of the mandibles of 3 monkeys (Macaca fascicularis). Three months later, 2 titanium plasma-coated cylindrical implants were placed in all quadrants of each monkey. During the surgical procedure, standardized dehiscence defects were produced buccally and lingually, mea suring 2.5 mm in width and 3 mm in height. Four different experimental situations were created: 2 sites in each monkey were covered with an ePTFE membrane (M), 2 were filled with the graft material (DBBM), 2 were filled with the graft material and also covered with a membrane (M+DBBM), and 2 control sites were neither grafted nor covered (C). The flaps were sutured to allow for primary healing. Linear measurements of bone height and width were calculated on histological specimens obtained 6 months following surgery. In addition, values for bone density and for surface fraction of graft to new bone contact were measured. Vertical bone growth along the implant surface of 100% (SD 0%) for M+DBBM, 91% (SD 9%) for M, 52% (SD 24%) for DBBM, and 42% (SD 35%) for C was measured. The width of the regenerated bone 1.5 mm above the bottom of the original defect, i.e. at the 50% mark of the vertical extension of the defect, in relation to the width at the bottom of the defect amounted to 97% (SD 2%) for M+DBBM, 85% (SD 9%) for M, 42% (SD 41%) for DBBM, and 23% (SD 31%) for C. Assessment of bone density within the confinement of the regenerated bone resulted in an increase of 30% (SD 11%) for M+DBBM, 45% (SD 20%) for M, 33% (SD 20%) for DBBM, and 22% (SD 23%) for C. The values for graft to new bone contact within this compartment amounted to 80% (SD 15%) for M+DBBM and 89% (SD 14%) for DBBM. In conclusion, BioOss® exhibited osteoconductive properties and hence can be recommended for GBR procedures in dehiscence defects with respect to vertical and horizontal growth of bone. © Munksgaard 1998.
Persistent Identifierhttp://hdl.handle.net/10722/154026
ISSN
2023 Impact Factor: 4.8
2023 SCImago Journal Rankings: 1.865
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHämmerle, CHFen_US
dc.contributor.authorChiantella, GCen_US
dc.contributor.authorKarring, Ten_US
dc.contributor.authorLang, NPen_US
dc.date.accessioned2012-08-08T08:22:52Z-
dc.date.available2012-08-08T08:22:52Z-
dc.date.issued1998en_US
dc.identifier.citationClinical Oral Implants Research, 1998, v. 9 n. 3, p. 151-162en_US
dc.identifier.issn0905-7161en_US
dc.identifier.urihttp://hdl.handle.net/10722/154026-
dc.description.abstractThe aim of the present experiment was to test the effect of a deproteinized bovine bone mineral (Bio-Oss®) on guided bone regeneration (GBR) in dehiscence defects around implants. The first 2 molars and all premolars were extracted on both sides of the mandibles of 3 monkeys (Macaca fascicularis). Three months later, 2 titanium plasma-coated cylindrical implants were placed in all quadrants of each monkey. During the surgical procedure, standardized dehiscence defects were produced buccally and lingually, mea suring 2.5 mm in width and 3 mm in height. Four different experimental situations were created: 2 sites in each monkey were covered with an ePTFE membrane (M), 2 were filled with the graft material (DBBM), 2 were filled with the graft material and also covered with a membrane (M+DBBM), and 2 control sites were neither grafted nor covered (C). The flaps were sutured to allow for primary healing. Linear measurements of bone height and width were calculated on histological specimens obtained 6 months following surgery. In addition, values for bone density and for surface fraction of graft to new bone contact were measured. Vertical bone growth along the implant surface of 100% (SD 0%) for M+DBBM, 91% (SD 9%) for M, 52% (SD 24%) for DBBM, and 42% (SD 35%) for C was measured. The width of the regenerated bone 1.5 mm above the bottom of the original defect, i.e. at the 50% mark of the vertical extension of the defect, in relation to the width at the bottom of the defect amounted to 97% (SD 2%) for M+DBBM, 85% (SD 9%) for M, 42% (SD 41%) for DBBM, and 23% (SD 31%) for C. Assessment of bone density within the confinement of the regenerated bone resulted in an increase of 30% (SD 11%) for M+DBBM, 45% (SD 20%) for M, 33% (SD 20%) for DBBM, and 22% (SD 23%) for C. The values for graft to new bone contact within this compartment amounted to 80% (SD 15%) for M+DBBM and 89% (SD 14%) for DBBM. In conclusion, BioOss® exhibited osteoconductive properties and hence can be recommended for GBR procedures in dehiscence defects with respect to vertical and horizontal growth of bone. © Munksgaard 1998.en_US
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLRen_US
dc.relation.ispartofClinical Oral Implants Researchen_US
dc.subjectAnimal-
dc.subjectBone formation-
dc.subjectBone graft-
dc.subjectDeproteinized bovine bone-
dc.subjectePTFE membrane-
dc.subjectGuided tissue regeneration-
dc.subjectJaw bone-
dc.subjectOsteoconductivity index-
dc.subject.meshAnimalsen_US
dc.subject.meshBone Densityen_US
dc.subject.meshBone Regenerationen_US
dc.subject.meshBone Substitutesen_US
dc.subject.meshBone Transplantation - Methodsen_US
dc.subject.meshCattleen_US
dc.subject.meshDental Implantation, Endosseousen_US
dc.subject.meshDental Implantsen_US
dc.subject.meshGuided Tissue Regeneration, Periodontal - Methodsen_US
dc.subject.meshMacaca Fascicularisen_US
dc.subject.meshMandible - Pathology - Physiology - Surgeryen_US
dc.subject.meshMembranes, Artificialen_US
dc.subject.meshMineralsen_US
dc.subject.meshOsseointegrationen_US
dc.subject.meshPolytetrafluoroethyleneen_US
dc.subject.meshTitaniumen_US
dc.subject.meshTooth Socketen_US
dc.titleThe effect of a deproteinized bovine bone mineral on bone regeneration around titanium dental implantsen_US
dc.typeArticleen_US
dc.identifier.emailLang, NP:nplang@hkucc.hku.hken_US
dc.identifier.authorityLang, NP=rp00031en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1034/j.1600-0501.1998.090302.x-
dc.identifier.pmid10530129-
dc.identifier.scopuseid_2-s2.0-0032082608en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032082608&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume9en_US
dc.identifier.issue3en_US
dc.identifier.spage151en_US
dc.identifier.epage162en_US
dc.identifier.isiWOS:000074240400002-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridHämmerle, CHF=7005331848en_US
dc.identifier.scopusauthoridChiantella, GC=6602325272en_US
dc.identifier.scopusauthoridKarring, T=35560651200en_US
dc.identifier.scopusauthoridLang, NP=7201577367en_US
dc.identifier.issnl0905-7161-

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