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Article: Fatal diffuse alveolar damage complicating acute myeloid leukemia with abnormal eosinophils and trisomy X

TitleFatal diffuse alveolar damage complicating acute myeloid leukemia with abnormal eosinophils and trisomy X
Authors
Wan, TSKYip, SFYeung, YMChan, LCMa, SK
KeywordsAbnormal eosinophils
AML
Cytogenetics
Diffuse alveolar damage
Trisomy X
Issue Date2002
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00277/index.htm
Citation
Annals Of Hematology, 2002, v. 81 n. 3, p. 167-169 How to Cite?
DOI: http://dx.doi.org/10.1007/s00277-001-0423-6
AbstractWe describe a case of acute myeloid leukemia (AML) with abnormal eosinophils in a 44-year-old Chinese woman that was complicated by diffuse alveolar damage (DAD) and pulmonary hemorrhage (PH) shortly after induction chemotherapy. Cytogenetic study of bone marrow cells at diagnosis showed a rare aberration of trisomy X (+X) as the sole acquired karyotypic abnormality. We speculate that tissue damage by cellular constituents of the abnormal eosinophils that were released on cell lysis after chemotherapy might be etiologically linked to the occurrence of fatal pulmonary complications.
Persistent Identifierhttp://hdl.handle.net/10722/148303
ISSN
0939-5555
2021 Impact Factor: 4.030
2020 SCImago Journal Rankings: 1.079
ISI Accession Number ID
WOS:000175035100009
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorWan, TSKen_US
dc.contributor.authorYip, SFen_US
dc.contributor.authorYeung, YMen_US
dc.contributor.authorChan, LCen_US
dc.contributor.authorMa, SKen_US
dc.date.accessioned2012-05-29T06:12:06Z-
dc.date.available2012-05-29T06:12:06Z-
dc.date.issued2002en_US
dc.identifier.citationAnnals Of Hematology, 2002, v. 81 n. 3, p. 167-169en_US
dc.identifier.issn0939-5555en_US
dc.identifier.urihttp://hdl.handle.net/10722/148303-
dc.description.abstractWe describe a case of acute myeloid leukemia (AML) with abnormal eosinophils in a 44-year-old Chinese woman that was complicated by diffuse alveolar damage (DAD) and pulmonary hemorrhage (PH) shortly after induction chemotherapy. Cytogenetic study of bone marrow cells at diagnosis showed a rare aberration of trisomy X (+X) as the sole acquired karyotypic abnormality. We speculate that tissue damage by cellular constituents of the abnormal eosinophils that were released on cell lysis after chemotherapy might be etiologically linked to the occurrence of fatal pulmonary complications.en_US
dc.languageengen_US
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00277/index.htmen_US
dc.relation.ispartofAnnals of Hematologyen_US
dc.subjectAbnormal eosinophils-
dc.subjectAML-
dc.subjectCytogenetics-
dc.subjectDiffuse alveolar damage-
dc.subjectTrisomy X-
dc.subject.meshAcute Diseaseen_US
dc.subject.meshAdulten_US
dc.subject.meshEosinophils - Pathologyen_US
dc.subject.meshFatal Outcomeen_US
dc.subject.meshFemaleen_US
dc.subject.meshHemorrhage - Complicationsen_US
dc.subject.meshHumansen_US
dc.subject.meshLeukemia, Myeloid - Complications - Genetics - Pathologyen_US
dc.subject.meshLung Diseases - Complicationsen_US
dc.subject.meshPulmonary Alveoli - Pathologyen_US
dc.subject.meshTrisomy - Geneticsen_US
dc.subject.meshX Chromosome - Geneticsen_US
dc.titleFatal diffuse alveolar damage complicating acute myeloid leukemia with abnormal eosinophils and trisomy Xen_US
dc.typeArticleen_US
dc.identifier.emailChan, LC:chanlc@hkucc.hku.hken_US
dc.identifier.authorityChan, LC=rp00373en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/s00277-001-0423-6en_US
dc.identifier.pmid11904745-
dc.identifier.scopuseid_2-s2.0-0036943733en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036943733&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume81en_US
dc.identifier.issue3en_US
dc.identifier.spage167en_US
dc.identifier.epage169en_US
dc.identifier.isiWOS:000175035100009-
dc.publisher.placeGermanyen_US
dc.identifier.issnl0939-5555-

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