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Article: Trisomy 14, deletion 20q and t(3;3) (q21;q26) in a case of myelodysplastic syndrome with myelofibrosis

TitleTrisomy 14, deletion 20q and t(3;3) (q21;q26) in a case of myelodysplastic syndrome with myelofibrosis
Authors
Keywordskaryotypic changes
myelodysplasia
myelofibrosis
Issue Date1994
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLH
Citation
Clinical And Laboratory Haematology, 1994, v. 16 n. 1, p. 79-84 How to Cite?
AbstractWe describe a patient with trilineage myelodysplasia and hyperplastic megakaryopoiesis associated with significant myelofibrosis at diagnosis, who developed acute myeloid leukaemia two months afterwards. The clinical and pathological features were consistent with a myelodysplasia/myelofibrosis syndrome with leukemic transformation. Cytogenetic investigation showed trisomy 14, del(20q) and t(3;3) (q21;q26). These findings are of possible significance in the understanding of the association between myelodysplasia and myelofibrosis.
Persistent Identifierhttp://hdl.handle.net/10722/148024
ISSN
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorKwong, YLen_HK
dc.contributor.authorWan, TSKen_HK
dc.contributor.authorLiang, Ren_HK
dc.contributor.authorChan, LCen_HK
dc.date.accessioned2012-05-29T06:10:26Z-
dc.date.available2012-05-29T06:10:26Z-
dc.date.issued1994en_HK
dc.identifier.citationClinical And Laboratory Haematology, 1994, v. 16 n. 1, p. 79-84en_HK
dc.identifier.issn0141-9854en_HK
dc.identifier.urihttp://hdl.handle.net/10722/148024-
dc.description.abstractWe describe a patient with trilineage myelodysplasia and hyperplastic megakaryopoiesis associated with significant myelofibrosis at diagnosis, who developed acute myeloid leukaemia two months afterwards. The clinical and pathological features were consistent with a myelodysplasia/myelofibrosis syndrome with leukemic transformation. Cytogenetic investigation showed trisomy 14, del(20q) and t(3;3) (q21;q26). These findings are of possible significance in the understanding of the association between myelodysplasia and myelofibrosis.en_HK
dc.languageengen_US
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLHen_HK
dc.relation.ispartofClinical and Laboratory Haematologyen_HK
dc.subjectkaryotypic changesen_HK
dc.subjectmyelodysplasiaen_HK
dc.subjectmyelofibrosisen_HK
dc.subject.meshChromosome Deletionen_US
dc.subject.meshChromosomes, Human, Pair 14en_US
dc.subject.meshChromosomes, Human, Pair 20en_US
dc.subject.meshChromosomes, Human, Pair 3en_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshKaryotypingen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMyelodysplastic Syndromes - Geneticsen_US
dc.subject.meshPrimary Myelofibrosis - Geneticsen_US
dc.subject.meshTranslocation, Geneticen_US
dc.subject.meshTrisomyen_US
dc.titleTrisomy 14, deletion 20q and t(3;3) (q21;q26) in a case of myelodysplastic syndrome with myelofibrosisen_HK
dc.typeArticleen_HK
dc.identifier.emailKwong, YL:ylkwong@hku.hken_HK
dc.identifier.emailLiang, R:rliang@hku.hken_HK
dc.identifier.emailChan, LC:chanlc@hkucc.hku.hken_HK
dc.identifier.authorityKwong, YL=rp00358en_HK
dc.identifier.authorityLiang, R=rp00345en_HK
dc.identifier.authorityChan, LC=rp00373en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid8039350-
dc.identifier.scopuseid_2-s2.0-0028341463en_HK
dc.identifier.volume16en_HK
dc.identifier.issue1en_HK
dc.identifier.spage79en_HK
dc.identifier.epage84en_HK
dc.identifier.isiWOS:A1994NF93100010-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridKwong, YL=7102818954en_HK
dc.identifier.scopusauthoridWan, TSK=25623981600en_HK
dc.identifier.scopusauthoridLiang, R=26643224900en_HK
dc.identifier.scopusauthoridChan, LC=7403540707en_HK
dc.identifier.issnl0141-9854-

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