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Article: Artemether-lumefantrine and primaquine for mixed Plasmodium falciparum and ovale malaria
Title | Artemether-lumefantrine and primaquine for mixed Plasmodium falciparum and ovale malaria |
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Authors | |
Keywords | Adult Article Case Report Clinical Feature Drug Substitution Female Glycogen Storage Disease Type 1 Human Laboratory Test Malaria Plasmodium Falciparum |
Issue Date | 2006 |
Citation | Journal Of Pharmacy Practice And Research, 2006, v. 36 n. 2, p. 134-135 How to Cite? |
Abstract | Aim: To present a case of uncomplicated mixed Plasmodium falciparum and ovale malaria requiring treatment with artemether-lumefantrine and primaquine. Clinical features: A 40-year-old female presented with a mixed infection of uncomplicated P. falciparum and ovale. Treatment was commenced with oral quinine sulphate 600 mg, 8-hourly which was changed to artemether-lumefantrine and primaquine. A glucose-6-phosphate-dehydrogenase test revealed deficiency, necessitating an alteration of the primaquine regimen. Discussion: Malaria infections are often initially treated with quinine if the infective species is not known or if the infection is mixed. Oral quinine remains useful in the treatment of uncomplicated P. falciparum malaria, however the six-dose regimen of artemether-lumefantrine is an effective alternative. Conclusion: This case highlights the benefits of artemether-lumefantrine for mixed-uncomplicated malaria and the use of primaquine for eradication of liver stages for P. ovale infections. |
Persistent Identifier | http://hdl.handle.net/10722/145483 |
ISSN | 2023 Impact Factor: 1.0 2023 SCImago Journal Rankings: 0.283 |
References |
DC Field | Value | Language |
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dc.contributor.author | Chan, EWY | en_HK |
dc.date.accessioned | 2012-02-23T12:11:07Z | - |
dc.date.available | 2012-02-23T12:11:07Z | - |
dc.date.issued | 2006 | en_HK |
dc.identifier.citation | Journal Of Pharmacy Practice And Research, 2006, v. 36 n. 2, p. 134-135 | en_HK |
dc.identifier.issn | 1445-937X | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/145483 | - |
dc.description.abstract | Aim: To present a case of uncomplicated mixed Plasmodium falciparum and ovale malaria requiring treatment with artemether-lumefantrine and primaquine. Clinical features: A 40-year-old female presented with a mixed infection of uncomplicated P. falciparum and ovale. Treatment was commenced with oral quinine sulphate 600 mg, 8-hourly which was changed to artemether-lumefantrine and primaquine. A glucose-6-phosphate-dehydrogenase test revealed deficiency, necessitating an alteration of the primaquine regimen. Discussion: Malaria infections are often initially treated with quinine if the infective species is not known or if the infection is mixed. Oral quinine remains useful in the treatment of uncomplicated P. falciparum malaria, however the six-dose regimen of artemether-lumefantrine is an effective alternative. Conclusion: This case highlights the benefits of artemether-lumefantrine for mixed-uncomplicated malaria and the use of primaquine for eradication of liver stages for P. ovale infections. | en_HK |
dc.language | eng | en_US |
dc.relation.ispartof | Journal of Pharmacy Practice and Research | en_HK |
dc.subject | Adult | en_US |
dc.subject | Article | en_US |
dc.subject | Case Report | en_US |
dc.subject | Clinical Feature | en_US |
dc.subject | Drug Substitution | en_US |
dc.subject | Female | en_US |
dc.subject | Glycogen Storage Disease Type 1 | en_US |
dc.subject | Human | en_US |
dc.subject | Laboratory Test | en_US |
dc.subject | Malaria | en_US |
dc.subject | Plasmodium Falciparum | en_US |
dc.title | Artemether-lumefantrine and primaquine for mixed Plasmodium falciparum and ovale malaria | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Chan, EWY: ewchan@hku.hk | en_HK |
dc.identifier.authority | Chan, EWY=rp01587 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.scopus | eid_2-s2.0-33746151229 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-33746151229&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 36 | en_HK |
dc.identifier.issue | 2 | en_HK |
dc.identifier.spage | 134 | en_HK |
dc.identifier.epage | 135 | en_HK |
dc.identifier.scopusauthorid | Chan, EWY=14043219000 | en_HK |
dc.identifier.issnl | 2055-2335 | - |