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Article: Change of psychotropic drug prescription for schizophrenia in a psychiatric institution in Beijing, China between 1999 and 2008

TitleChange of psychotropic drug prescription for schizophrenia in a psychiatric institution in Beijing, China between 1999 and 2008
Authors
KeywordsChina
Clozapine
Prescription pattern
Psychotropic drugs
Schizophrenia
Issue Date2010
PublisherDustri-Verlag Dr. Karl Feistle. The Journal's web site is located at http://www.dustri.com/nc/journals-in-english/mag/int-journal-of-clinical-pharmacology-and-therapeutics.html
Citation
International Journal Of Clinical Pharmacology And Therapeutics, 2010, v. 48 n. 4, p. 270-274 How to Cite?
AbstractBackground: To date, no study has investigated how prescription patterns change over time in Chinese patients with schizophrenia. This study aimed to determine psychotropic drug prescription patterns and the use of electroconvulsive therapy (ECT) for schizophrenia and their changes over time in a large psychiatric institution in Beijing, China. Methods: The case notes of inpatients with schizophrenia were scrutinized to identify psychotropic drug prescription patterns and the use of ECT on November 10, 1999 and the same calendar day in 2008 and to compare the two surveys. Results: In 1999, 45.1% of inpatients with schizophrenia were on first-generation antipsychotic drugs (FGA), while 52.9% were on second-generation antipsychotic drugs (SGA). In 2008, the percentage of patients on FGAs decreased to 15.1%, while those on SGAs increased to 77.2%. The proportion of schizophrenia patients on mood stabilizers and antidepressants rose from 3.3% and 4.3% in 1999 to 18% and 9.5% by 2008, respectively. Use of ECT grew from 0.5% in 1999 to 5.6% by 2008. The proportion of schizophrenia patients not prescribed antipsychotic drugs changed from 5.6% in 1999 to 13.7% in 2008. Conclusions: The prescription pattern of psychotropic drugs changes considerably over time, even in the same clinical setting. Mental health professionals need to keep up with changes in the prescription patterns of psychotropic drugs in order to serve their patients at the best possible level. The socio-economic reasons for not prescribing antipsychotic drugs to schizophrenia patients should be further explored. ©2010 Dustri-Verlag Dr. K. Feistle.
Persistent Identifierhttp://hdl.handle.net/10722/144300
ISSN
2023 Impact Factor: 0.9
2023 SCImago Journal Rankings: 0.261
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorAn, FRen_HK
dc.contributor.authorXiang, YTen_HK
dc.contributor.authorWang, CYen_HK
dc.contributor.authorZhang, GPen_HK
dc.contributor.authorChiu, HFKen_HK
dc.contributor.authorChan, SSMen_HK
dc.contributor.authorLee, EHMen_HK
dc.contributor.authorUngvari, GSen_HK
dc.date.accessioned2012-01-20T09:00:22Z-
dc.date.available2012-01-20T09:00:22Z-
dc.date.issued2010en_HK
dc.identifier.citationInternational Journal Of Clinical Pharmacology And Therapeutics, 2010, v. 48 n. 4, p. 270-274en_HK
dc.identifier.issn0946-1965en_HK
dc.identifier.urihttp://hdl.handle.net/10722/144300-
dc.description.abstractBackground: To date, no study has investigated how prescription patterns change over time in Chinese patients with schizophrenia. This study aimed to determine psychotropic drug prescription patterns and the use of electroconvulsive therapy (ECT) for schizophrenia and their changes over time in a large psychiatric institution in Beijing, China. Methods: The case notes of inpatients with schizophrenia were scrutinized to identify psychotropic drug prescription patterns and the use of ECT on November 10, 1999 and the same calendar day in 2008 and to compare the two surveys. Results: In 1999, 45.1% of inpatients with schizophrenia were on first-generation antipsychotic drugs (FGA), while 52.9% were on second-generation antipsychotic drugs (SGA). In 2008, the percentage of patients on FGAs decreased to 15.1%, while those on SGAs increased to 77.2%. The proportion of schizophrenia patients on mood stabilizers and antidepressants rose from 3.3% and 4.3% in 1999 to 18% and 9.5% by 2008, respectively. Use of ECT grew from 0.5% in 1999 to 5.6% by 2008. The proportion of schizophrenia patients not prescribed antipsychotic drugs changed from 5.6% in 1999 to 13.7% in 2008. Conclusions: The prescription pattern of psychotropic drugs changes considerably over time, even in the same clinical setting. Mental health professionals need to keep up with changes in the prescription patterns of psychotropic drugs in order to serve their patients at the best possible level. The socio-economic reasons for not prescribing antipsychotic drugs to schizophrenia patients should be further explored. ©2010 Dustri-Verlag Dr. K. Feistle.en_HK
dc.languageengen_US
dc.publisherDustri-Verlag Dr. Karl Feistle. The Journal's web site is located at http://www.dustri.com/nc/journals-in-english/mag/int-journal-of-clinical-pharmacology-and-therapeutics.html-
dc.relation.ispartofInternational Journal of Clinical Pharmacology and Therapeuticsen_HK
dc.subjectChinaen_HK
dc.subjectClozapineen_HK
dc.subjectPrescription patternen_HK
dc.subjectPsychotropic drugsen_HK
dc.subjectSchizophreniaen_HK
dc.titleChange of psychotropic drug prescription for schizophrenia in a psychiatric institution in Beijing, China between 1999 and 2008en_HK
dc.typeArticleen_HK
dc.identifier.emailLee, EHM: edwinlhm@hku.hken_HK
dc.identifier.authorityLee, EHM=rp01575en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid20353748en_HK
dc.identifier.scopuseid_2-s2.0-77951009397en_HK
dc.identifier.hkuros224714-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77951009397&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume48en_HK
dc.identifier.issue4en_HK
dc.identifier.spage270en_HK
dc.identifier.epage274en_HK
dc.identifier.isiWOS:000277399900004-
dc.identifier.scopusauthoridAn, FR=8644333000en_HK
dc.identifier.scopusauthoridXiang, YT=35241398400en_HK
dc.identifier.scopusauthoridWang, CY=35345843000en_HK
dc.identifier.scopusauthoridZhang, GP=36097285800en_HK
dc.identifier.scopusauthoridChiu, HFK=24447976700en_HK
dc.identifier.scopusauthoridChan, SSM=13409371900en_HK
dc.identifier.scopusauthoridLee, EHM=7406967099en_HK
dc.identifier.scopusauthoridUngvari, GS=7006092063en_HK
dc.identifier.issnl0946-1965-

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